ATE197800T1 - Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor - Google Patents

Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor

Info

Publication number: ATE197800T1
Authority: AT; Austria
Prior art keywords: cells; growth factor; protein; kgf; epithelial cells
Prior art date: 1989-01-31

Application number

AT90903253T

Other languages

English (en)

Inventor

Jeffrey S Rubin

Paul W Finch

Stuart A Aaronson

Original Assignee

Jeffrey S Rubin

Paul W Finch

Stuart A Aaronson

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-31

Filing date

1990-01-30

Publication date

2000-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23175833&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE197800(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-01-30 Application filed by Jeffrey S Rubin, Paul W Finch, Stuart A Aaronson filed Critical Jeffrey S Rubin

2000-12-15 Application granted granted Critical

2000-12-15 Publication of ATE197800T1 publication Critical patent/ATE197800T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Immunology (AREA)
Analytical Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Dermatology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)

AT90903253T 1989-01-31 1990-01-30 Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor ATE197800T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US30428189A	1989-01-31	1989-01-31
PCT/US1990/000418 WO1990008771A1 (en)	1989-01-31	1990-01-30	Dna encoding a growth factor specific for epithelial cells

Publications (1)

Publication Number	Publication Date
ATE197800T1 true ATE197800T1 (de)	2000-12-15

Family

ID=23175833

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90903253T ATE197800T1 (de)	1989-01-31	1990-01-30	Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor

Country Status (22)

Country	Link
US (8)	US5665870A (de)
EP (2)	EP0555205B1 (de)
JP (6)	JP3298874B2 (de)
KR (1)	KR950012805B1 (de)
AT (1)	ATE197800T1 (de)
AU (2)	AU647732B2 (de)
CA (2)	CA2349875C (de)
DE (2)	DE69033668T2 (de)
DK (1)	DK0555205T3 (de)
ES (1)	ES2153816T3 (de)
FI (1)	FI114711B (de)
GE (1)	GEP20022681B (de)
HU (1)	HU218090B (de)
IE (1)	IE20020188A1 (de)
LT (1)	LT3472B (de)
LU (1)	LU91237I2 (de)
LV (1)	LV10284B (de)
NL (1)	NL300230I2 (de)
NO (2)	NO308312B1 (de)
RU (1)	RU2250213C2 (de)
SG (1)	SG46699A1 (de)
WO (1)	WO1990008771A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
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AU647732B2 (en)	1989-01-31	1994-03-31	Stuart A. Aaronson	DNA encoding a growth factor specific for epithelial cells
GB9203533D0 (en) *	1992-02-19	1992-04-08	Erba Carlo Spa	Use of the conjugate between a fibroblast growth factor and a saporin in treating ocular pathologies
US5814605A (en) *	1993-03-26	1998-09-29	Amgen Inc.	Therapeutic uses of keratinocyte growth factor
RU2146148C1 (ru) *	1993-03-26	2000-03-10	Амген Инк.	Терапевтическое применение фактора роста кератиноцитов (фрк)
US7084119B2 (en)	1993-06-29	2006-08-01	Chiron Corporation	Truncated keratinocyte growth factor (KGF) having increased biological activity
DE69434053T2 (de)	1993-06-29	2006-02-23	Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville	Verkürzter keratinocytenwachstumsfaktor(kgf)mit erhöhter biologischer aktivität
US6268212B1 (en)	1993-10-18	2001-07-31	Amgen Inc.	Tissue specific transgene expression
PL182888B1 (pl) *	1994-10-13	2002-03-29	Amgen Inc	Analog rodzimego keratynocytowego czynnika wzrostu-KGF, cząsteczka rekombinacyjnego kwasu nukleinowego, kodującego analog KGF, biologicznie funkcjonalny wektor zawierający rekombinacyjny kwas nukleinowy kodujący analog KGF, komórka gospodarza zawierająca rekombinacyjny kwas nukleinowy, kodujący analog KGF lub biologicznie funkcjonalny wektor zawierający taki kwas nukleinowy oraz sposób wytwarzania analoga KGF
MX9702665A (es) *	1994-10-13	1997-07-31	Amgen Inc	Analogos del factor de crecimiento de queratinocitos.
US6008328A (en) *	1994-10-13	1999-12-28	Amgen Inc.	Method for purifying keratinocyte growth factors
CN1161380C (zh) *	1994-10-13	2004-08-11	安姆根有限公司	角化细胞生长因子的纯化方法
US6818439B1 (en)	1994-12-30	2004-11-16	Chiron Corporation	Methods for administration of recombinant gene delivery vehicles for treatment of hemophilia and other disorders
US6030613A (en)	1995-01-17	2000-02-29	The Brigham And Women's Hospital, Inc.	Receptor specific transepithelial transport of therapeutics
US6077692A (en)	1995-02-14	2000-06-20	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
US6693077B1 (en)	1995-02-14	2004-02-17	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
US7232667B2 (en)	1995-02-14	2007-06-19	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 polynucleotides
DE69637332T2 (de)	1995-10-11	2008-10-09	Novartis Vaccines and Diagnostics, Inc., Emeryville	Kombinierung von PDGF, KGF, IGF und IGFBP für Wundheilung
US6692961B1 (en)	1996-10-11	2004-02-17	Invitrogen Corporation	Defined systems for epithelial cell culture and use thereof
US6743422B1 (en)	1996-10-15	2004-06-01	Amgen, Inc.	Keratinocyte growth factor-2 products
US20030144202A1 (en) *	1996-10-15	2003-07-31	Amgen Inc.	Uses of keratinocyte growth factor-2
DE19716098A1 (de) *	1997-04-17	1998-10-22	Univ Ludwigs Albert	Fibroblasten mit einem Fremdgen enthaltende Zusammensetzung zur Behandlung von Wunden
US6228839B1 (en)	1997-12-19	2001-05-08	Emory University	Use of keratinocyte growth factor to improve oxidative status
AU1905799A (en) *	1997-12-22	1999-07-12	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 formulations
US6869927B1 (en)	1997-12-22	2005-03-22	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 formulations
CN1295579A (zh) *	1998-02-13	2001-05-16	人类基因组科学公司	角质细胞生长因子2的治疗应用
US6335317B1 (en)	1998-04-10	2002-01-01	Emory University	Use of gut-trophic growth factors to improve oxidative status
US6313103B1 (en)	1998-05-13	2001-11-06	Carrington Laboratories, Inc.	Pectic substance as a growth factor stabilizer
US7022683B1 (en)	1998-05-13	2006-04-04	Carrington Laboratories, Inc.	Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
US5929051A (en) *	1998-05-13	1999-07-27	Carrington Laboratories, Inc.	Aloe pectins
US6372494B1 (en) *	1999-05-14	2002-04-16	Advanced Tissue Sciences, Inc.	Methods of making conditioned cell culture medium compositions
US6371984B1 (en) *	1999-09-13	2002-04-16	Keraplast Technologies, Ltd.	Implantable prosthetic or tissue expanding device
US6783546B2 (en)	1999-09-13	2004-08-31	Keraplast Technologies, Ltd.	Implantable prosthetic or tissue expanding device
US6395414B1 (en)	2000-02-11	2002-05-28	General Motors Corporation	Staged venting of fuel cell system during rapid shutdown
US6376112B1 (en)	2000-02-11	2002-04-23	General Motors Corporation	Controlled shutdown of a fuel cell
US6413662B1 (en)	2000-02-22	2002-07-02	General Motors Corporation	Fuel cell system shutdown with anode pressure control
JP2001302691A (ja) *	2000-04-17	2001-10-31	Nichirei Corp	ヒトｋｇｆに対する抗体
AU2002309473A1 (en) *	2001-01-08	2002-10-08	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
PL362414A1 (en)	2001-02-19	2004-11-02	Merck Patent Gmbh	Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity
US7494669B2 (en)	2001-02-28	2009-02-24	Carrington Laboratories, Inc.	Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
MXPA04001526A (es)	2001-08-21	2004-05-31	Chiron Corp	Composiciones de polipetidos kgf.
US7202066B2 (en) *	2002-01-29	2007-04-10	Carrington Laboratories, Inc.	Combination of a growth factor and a protease enzyme
GB0206309D0 (en) *	2002-03-16	2002-05-01	Axordia Ltd	Isolated cells
US20050074773A1 (en) *	2002-08-20	2005-04-07	Shimkets Richard A.	Methods for diagnosing and treatment of conditions that alter phosphate transport in mammals
US8304387B2 (en)	2004-12-15	2012-11-06	Swedish Orphan Biovitrum Ab (Publ)	Therapeutic formulations of keratinocyte growth factor
WO2008005533A2 (en) *	2006-07-06	2008-01-10	Aaron Thomas Tabor	Compositions and methods for genetic modification of cells having cosmetic function to enhance cosmetic appearance
PL2125878T3 (pl) *	2007-01-05	2013-08-30	Helix Biomedix Inc	Krótkie, aktywne biologicznie peptydy do komórkowych i immunologicznych modulacji
BR112012000865A2 (pt)	2009-07-17	2019-09-24	T Tabor Aaron	"composição e método para a modificação genética cosmética de células substancialmente intactas"
EP2875359A4 (de)	2012-03-30	2015-08-19	Charles R Drew University Of Medicine And Science	Zusammensetzungen und verfahren zur behandlung oder prävention von stoffwechselsyndromerkrankungen
KR102277147B1 (ko) *	2017-12-13	2021-07-13	건국대학교 산학협력단	섬유아 성장인자 유래 펩타이드의 골 또는 연골 분화 촉진 용도

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US5096825A (en) *	1983-01-12	1992-03-17	Chiron Corporation	Gene for human epidermal growth factor and synthesis and expression thereof
US4444760A (en) *	1983-06-17	1984-04-24	Merck & Co., Inc.	Purification and characterization of a protein fibroblast growth factor
US4473679A (en)	1983-12-12	1984-09-25	Borg-Warner Chemicals, Inc.	Thermoplastic acrylic elastomers
US4743679A (en) *	1986-02-24	1988-05-10	Creative Biomolecules, Inc.	Process for producing human epidermal growth factor and analogs thereof
US4868113A (en)	1986-03-03	1989-09-19	Rorer Biotechnology, Inc.	Recombinant DNA vector encoding human endothelial cell growth factor
US4983679A (en)	1986-05-29	1991-01-08	E. I. Dupont De Nemours And Company	β-(keto or sulfonyl)esters from reaction of silylketene acetal and acyl or sulfonyl compound
AU617795B2 (en)	1988-03-17	1991-12-05	Leukotech A/S	Heparin-binding proteins, dna coding for them, processes for producing them as well as therapeutic preparations containing them
AU647732B2 (en)	1989-01-31	1994-03-31	Stuart A. Aaronson	DNA encoding a growth factor specific for epithelial cells
DE69434053T2 (de)	1993-06-29	2006-02-23	Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville	Verkürzter keratinocytenwachstumsfaktor(kgf)mit erhöhter biologischer aktivität
PL182888B1 (pl)	1994-10-13	2002-03-29	Amgen Inc	Analog rodzimego keratynocytowego czynnika wzrostu-KGF, cząsteczka rekombinacyjnego kwasu nukleinowego, kodującego analog KGF, biologicznie funkcjonalny wektor zawierający rekombinacyjny kwas nukleinowy kodujący analog KGF, komórka gospodarza zawierająca rekombinacyjny kwas nukleinowy, kodujący analog KGF lub biologicznie funkcjonalny wektor zawierający taki kwas nukleinowy oraz sposób wytwarzania analoga KGF

1990
- 1990-01-30 AU AU50496/90A patent/AU647732B2/en not_active Expired
- 1990-01-30 JP JP50341390A patent/JP3298874B2/ja not_active Expired - Lifetime
- 1990-01-30 SG SG1996008633A patent/SG46699A1/en unknown
- 1990-01-30 RU SU5001740/13A patent/RU2250213C2/ru active
- 1990-01-30 HU HU998/90A patent/HU218090B/hu unknown
- 1990-01-30 ES ES90903253T patent/ES2153816T3/es not_active Expired - Lifetime
- 1990-01-30 EP EP90903253A patent/EP0555205B1/de not_active Expired - Lifetime
- 1990-01-30 WO PCT/US1990/000418 patent/WO1990008771A1/en active IP Right Grant
- 1990-01-30 AT AT90903253T patent/ATE197800T1/de active
- 1990-01-30 GE GEAP1990983A patent/GEP20022681B/en unknown
- 1990-01-30 EP EP00103140A patent/EP1016716A3/de not_active Withdrawn
- 1990-01-30 DK DK90903253T patent/DK0555205T3/da active
- 1990-01-30 DE DE69033668T patent/DE69033668T2/de not_active Expired - Lifetime
- 1990-01-31 IE IE20020188A patent/IE20020188A1/en not_active Application Discontinuation
- 1990-09-29 KR KR90702202A patent/KR950012805B1/ko not_active IP Right Cessation
1991
- 1991-03-15 CA CA2349875A patent/CA2349875C/en not_active Expired - Lifetime
- 1991-03-15 CA CA002038398A patent/CA2038398C/en not_active Expired - Lifetime
- 1991-07-30 FI FI913637A patent/FI114711B/fi active
1992
- 1992-12-23 LV LVP-92-410A patent/LV10284B/xx unknown
1993
- 1993-06-21 LT LTIP667A patent/LT3472B/lt not_active IP Right Cessation
1994
- 1994-06-28 AU AU65986/94A patent/AU684278B2/en not_active Expired
1995
- 1995-05-31 US US08/455,628 patent/US5665870A/en not_active Expired - Lifetime
- 1995-05-31 US US08/455,641 patent/US5707805A/en not_active Expired - Lifetime
- 1995-05-31 US US08/455,975 patent/US6833132B1/en not_active Expired - Lifetime
- 1995-05-31 US US08/455,672 patent/US5741642A/en not_active Expired - Lifetime
- 1995-05-31 US US08/455,655 patent/US5654405A/en not_active Expired - Lifetime
- 1995-05-31 US US08/455,620 patent/US6420531B1/en not_active Expired - Lifetime
- 1995-06-07 US US08/477,982 patent/US6709842B1/en not_active Expired - Lifetime
- 1995-06-07 US US08/480,948 patent/US5731170A/en not_active Expired - Lifetime
- 1995-12-27 JP JP7341890A patent/JP2716416B2/ja not_active Expired - Lifetime
1997
- 1997-05-16 NO NO972259A patent/NO308312B1/no not_active IP Right Cessation
- 1997-06-06 NO NO972617A patent/NO308310B1/no not_active IP Right Cessation
- 1997-10-22 JP JP09290175A patent/JP3088983B2/ja not_active Expired - Lifetime
1999
- 1999-10-06 JP JP28551799A patent/JP3802292B2/ja not_active Expired - Lifetime
2000
- 2000-10-11 JP JP2000311208A patent/JP3802329B2/ja not_active Expired - Lifetime
2006
- 2006-03-06 JP JP2006060217A patent/JP2006149407A/ja not_active Withdrawn
- 2006-04-11 DE DE200612000021 patent/DE122006000021I1/de active Pending
- 2006-04-19 NL NL300230C patent/NL300230I2/nl unknown
- 2006-04-24 LU LU91237C patent/LU91237I2/fr unknown

Also Published As

Publication number	Publication date
HU218090B (hu)	2000-05-28
DK0555205T3 (da)	2001-03-05
JPH10243800A (ja)	1998-09-14
JP3298874B2 (ja)	2002-07-08
CA2349875C (en)	2010-02-09
US6709842B1 (en)	2004-03-23
US5654405A (en)	1997-08-05
JP2716416B2 (ja)	1998-02-18
EP0555205B1 (de)	2000-11-29
JP2006149407A (ja)	2006-06-15
US6833132B1 (en)	2004-12-21
JP2001157594A (ja)	2001-06-12
WO1990008771A1 (en)	1990-08-09
CA2349875A1 (en)	1992-09-16
US5731170A (en)	1998-03-24
US5741642A (en)	1998-04-21
AU647732B2 (en)	1994-03-31
DE69033668T2 (de)	2001-04-12
EP0555205A4 (de)	1992-06-02
DE122006000021I1 (de)	2006-07-13
NO308312B1 (no)	2000-08-28
FI913637A0 (fi)	1991-07-30
IE20020188A1 (en)	2002-06-26
NO972259L (no)	1997-05-16
LU91237I2 (fr)	2007-02-22
NO972617L (no)	1997-06-06
JPH08277227A (ja)	1996-10-22
ES2153816T3 (es)	2001-03-16
AU5049690A (en)	1990-08-24
JP3802329B2 (ja)	2006-07-26
AU6598694A (en)	1994-09-08
NO308310B1 (no)	2000-08-28
LTIP667A (en)	1995-01-31
EP1016716A2 (de)	2000-07-05
CA2038398A1 (en)	1992-09-16
DE69033668D1 (de)	2001-01-04
LV10284A (lv)	1994-10-20
JPH04504415A (ja)	1992-08-06
HUT58759A (en)	1992-03-30
NL300230I1 (nl)	2006-07-03
SG46699A1 (en)	1998-02-20
EP0555205A1 (de)	1993-08-18
JP3802292B2 (ja)	2006-07-26
KR910700257A (ko)	1991-03-14
US5665870A (en)	1997-09-09
NO972617D0 (no)	1997-06-06
NL300230I2 (nl)	2006-09-01
US5707805A (en)	1998-01-13
FI114711B (fi)	2004-12-15
JP2000102396A (ja)	2000-04-11
JP3088983B2 (ja)	2000-09-18
US6420531B1 (en)	2002-07-16
EP1016716A3 (de)	2000-07-12
CA2038398C (en)	2002-01-22
LV10284B (en)	1995-04-20
KR950012805B1 (en)	1995-10-21
GEP20022681B (en)	2002-04-25
AU684278B2 (en)	1997-12-11
NO972259D0 (no)	1997-05-16
LT3472B (en)	1995-10-25
RU2250213C2 (ru)	2005-04-20

Publication	Publication Date	Title
ATE197800T1 (de)	2000-12-15	Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor
NO963371L (no)	1996-10-11	Hematopoietisk protein samt materialer og fremgangsmåter for fremstilling av det
ATE135371T1 (de)	1996-03-15	Mit akuter pankreatitis assoziiertes protein, mittel zur diagnose von akuter pankreatitis
FI820075L (fi)	1982-07-17	Rekombination-dna-medel och foerfarande
DE3881776D1 (de)	1993-07-22	Dns-konstruktionen, enthaltend eine kluyveromyces-alpha-factor-leadersequenz zur leitung der sekretion von heterologen polypeptiden.
DE69636621D1 (de)	2006-11-23	Verwendung von chimären proteinen im transport von ausgewählten substanten in die zelle
ATE199095T1 (de)	2001-02-15	Heparin bindendes mitogen mit homologie zum epidermis wachstumsfaktor (egf)
HUP0002472A2 (hu)	2000-10-28	Izolált dendritikus sejtmembrán-fehérje gének
DE69029808D1 (de)	1997-03-06	Monoklonale antikörper
CA2044626A1 (en)	1990-08-10	Type a platelet-derived growth factor receptor gene
ES2069303T3 (es)	1995-05-01	Proteinas 2b inflamatorias del macrofago humano.
FR2653445B1 (fr)	1994-07-29	Fragment d'adnc codant pour le gene du recepteur de l'interferon alpha et procede de preparation d'une proteine correspondante.
EP0286147A3 (de)	1990-05-16	Insulin-bindende Peptide und deren Verwendung
DE3853955D1 (de)	1995-07-13	Ein gen, das für glukuronidpermeas kodiert.
DE69932644D1 (de)	2006-09-14	Menschliches Protein mit in vitro antiproliferativer Aktivität.
ATE124722T1 (de)	1995-07-15	Für das plazentaprotein 9 (pp9) kodierende cdna, ihre isolierung und verwendung.