ATE195255T1 - Modifizierter,verbesserter,lebender brsv impfstoff - Google Patents

Modifizierter,verbesserter,lebender brsv impfstoff

Info

Publication number: ATE195255T1
Authority: AT; Austria
Prior art keywords: immunity; adjuvant; brsv; improved; polyoxypropylene
Prior art date: 1994-05-10

Application number

AT95918442T

Other languages

English (en)

Inventor

Hsien-Jue Chu

Original Assignee

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-10

Filing date

1995-05-08

Publication date

2000-08-15

1995-05-08 Application filed by American Home Prod filed Critical American Home Prod

2000-08-15 Application granted granted Critical

2000-08-15 Publication of ATE195255T1 publication Critical patent/ATE195255T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Immunology (AREA)
Mycology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT95918442T 1994-05-10 1995-05-08 Modifizierter,verbesserter,lebender brsv impfstoff ATE195255T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24037394A	1994-05-10	1994-05-10
PCT/US1995/006053 WO1995030437A1 (en)	1994-05-10	1995-05-08	Improved modified live brsv vaccine

Publications (1)

Publication Number	Publication Date
ATE195255T1 true ATE195255T1 (de)	2000-08-15

Family

ID=22906268

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT99115633T ATE365049T1 (de)	1994-05-10	1995-05-08	Abgeänderter, verbesserter brsv lebend- impfstoff
AT95918442T ATE195255T1 (de)	1994-05-10	1995-05-08	Modifizierter,verbesserter,lebender brsv impfstoff

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT99115633T ATE365049T1 (de)	1994-05-10	1995-05-08	Abgeänderter, verbesserter brsv lebend- impfstoff

Country Status (20)

Country	Link
US (2)	US5733555A (de)
EP (4)	EP0968722B1 (de)
JP (3)	JP3993230B2 (de)
KR (1)	KR100374434B1 (de)
CN (1)	CN1268393C (de)
AT (2)	ATE365049T1 (de)
AU (1)	AU711350B2 (de)
BR (1)	BR9507717A (de)
CA (1)	CA2189979C (de)
DE (2)	DE69518316T2 (de)
DK (2)	DK0968722T3 (de)
ES (3)	ES2429401T3 (de)
GR (1)	GR3034402T3 (de)
HK (1)	HK1024412A1 (de)
MY (1)	MY111829A (de)
NZ (1)	NZ285324A (de)
PT (3)	PT1820512E (de)
SI (2)	SI0759780T1 (de)
WO (1)	WO1995030437A1 (de)
ZA (1)	ZA953703B (de)

Families Citing this family (60)

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US6673335B1 (en) *	1992-07-08	2004-01-06	Nektar Therapeutics	Compositions and methods for the pulmonary delivery of aerosolized medicaments
DE69332105T2 (de) *	1992-09-29	2003-03-06	Inhale Therapeutic Systems, San Carlos	Pulmonale abgabe von aktiven fragmenten des parathormons
CA2136677A1 (en) *	1993-12-29	1995-06-30	Intervet, Inc.	Method of intranasally administering to bovines a trivalent vaccine containing modified live ibrv, pl3v and brsv
KR100419037B1 (ko) *	1994-03-07	2004-06-12	넥타르 테라퓨틱스	폐를통한인슐린의전달방법및그조성물
US20030113273A1 (en) *	1996-06-17	2003-06-19	Patton John S.	Methods and compositions for pulmonary delivery of insulin
ATE365049T1 (de) *	1994-05-10	2007-07-15	Wyeth Corp	Abgeänderter, verbesserter brsv lebend- impfstoff
ATE299892T1 (de) *	1994-05-18	2005-08-15	Nektar Therapeutics	Methoden und zusammensetzungen für die trockenpuderarznei aus interferonen
US6290991B1 (en)	1994-12-02	2001-09-18	Quandrant Holdings Cambridge Limited	Solid dose delivery vehicle and methods of making same
ATE322289T1 (de) *	1994-10-05	2006-04-15	Univ Vanderbilt	Interleukin-12 als adjuvans für paramyoxviridae impfstoffe
US6359054B1 (en) *	1994-11-18	2002-03-19	Supratek Pharma Inc.	Polynucleotide compositions for intramuscular administration
US20030035778A1 (en) *	1997-07-14	2003-02-20	Robert Platz	Methods and compositions for the dry powder formulation of interferon
US20060165606A1 (en)	1997-09-29	2006-07-27	Nektar Therapeutics	Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) *	1997-09-29	2001-10-30	Inhale Therapeutic Systems, Inc.	Stabilized preparations for use in metered dose inhalers
US6565885B1 (en)	1997-09-29	2003-05-20	Inhale Therapeutic Systems, Inc.	Methods of spray drying pharmaceutical compositions
US6908618B2 (en)	1997-11-10	2005-06-21	University Of Maryland	Production of novel bovine respiratory syncytial viruses from cDNAs
FR2772047B1 (fr) *	1997-12-05	2004-04-09	Ct Nat D Etudes Veterinaires E	Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
FR2775601B1 (fr) *	1998-03-03	2001-09-21	Merial Sas	Vaccins vivants recombines et adjuves
TW440845B (en)	1999-08-11	2001-06-16	Ibm	Method and system for programming FPGAs on PC-cards without additional hardware
US8404217B2 (en) *	2000-05-10	2013-03-26	Novartis Ag	Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
MXPA02001323A (es)	2000-05-10	2004-07-16	Alliance Pharma	Microgranulos con base fosfolipida para la liberacion de farmaco.
US7871598B1 (en) *	2000-05-10	2011-01-18	Novartis Ag	Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
AU2001280934A1 (en) *	2000-07-28	2002-02-13	Alliance Pharmaceutical Corp.	Methods and compositions to upregulate, redirect or limit immune responses to bioactive compounds
MY129765A (en)	2000-12-19	2007-04-30	Wyeth Corp	Improved mycoplasma hyopneumoniae bacterin vaccine
US7018638B2 (en)	2000-12-19	2006-03-28	Wyeth	Mycoplasma hyopneumoniae bacterin vaccine
WO2002091994A2 (en)	2001-05-10	2002-11-21	Wyeth	Composition and method for increasing cell density in cell cultures infected with lentivirus
ES2312580T5 (es)	2001-07-02	2017-12-11	Zoetis Services Llc	Vacunación en dosis única con l Mycoplasma hyopneumoniae /l
RS53184B (en) *	2001-07-27	2014-06-30	Zoetis W Llc	COMPOSITION OF VACCINES FOR ADMINISTRATION FOR PREVENTING OR DETERMINING WEST NIL ENCEPHALITIS IN EQUID
US20030129161A1 (en) *	2001-09-17	2003-07-10	Hsien-Jue Chu	Interleukin-12 as a veterinary vaccine adjuvant
SI1458360T1 (sl)	2001-12-19	2011-08-31	Novartis Ag	Pulmonalno dajanje aminoglikozidov
NZ538394A (en) *	2002-08-26	2008-06-30	Pfizer Prod Inc	Vaccine for respiratory and reproductive system infections in cattles
CA2551026A1 (en) *	2003-12-23	2005-07-14	Schering Corporation	Methods for producing a549 cell lines stable in serum-free medium suspension culture
US7700285B1 (en)	2005-12-29	2010-04-20	Boehringer Ingelheim Vetmedica, Inc.	PCV2 immunogenic compositions and methods of producing such compositions
US7833707B2 (en)	2004-12-30	2010-11-16	Boehringer Ingelheim Vetmedica, Inc.	Methods of overexpression and recovery of porcine circovirus type 2 ORF2
UA95602C2 (ru)	2004-12-30	2011-08-25	Берингер Ингельхейм Ветмедика, Инк.	Иммуногенная композиция цвс2 и способы приготовления такой композиции
US8097288B1 (en) *	2008-04-16	2012-01-17	Pom Wonderful, Llc	Composition and method for providing nutritional immunology for production animals
US20070031342A1 (en) *	2005-06-22	2007-02-08	Nektar Therapeutics	Sustained release microparticles for pulmonary delivery
AU2006278654A1 (en) *	2005-08-04	2007-02-15	Wyeth	Stabilizers for veterinary vaccines
MX365868B (es)	2005-12-29	2019-06-18	Boehringer Ingelheim Vetmedica Inc	Composiciones inmunogenicas de pcv2 multivalentes y metodos de producir composiciones de este tipo.
PT2371383E (pt)	2005-12-29	2015-11-24	Boehringer Ingelheim Vetmed	Utilização de uma composição imunogénica de pcv2 para atenuar os sintomas clínicos em porcos
EP1911836A1 (de) *	2006-10-12	2008-04-16	AVIR Green Hills Biotechnology Trading GmbH	Mediumzusatz für die Virusproduktion
EP2859900A1 (de)	2006-12-11	2015-04-15	Boehringer Ingelheim Vetmedica, Inc.	Wirksames Verfahren zur Behandlung von Infektionen mit dem porcinen Circovirus und Lawsonia intracellularis
HUE044410T2 (hu) *	2006-12-15	2019-10-28	Boehringer Ingelheim Animal Health Usa Inc	Egydózisú anti-PCV2 sertés vakcina
EP1941903A1 (de)	2007-01-03	2008-07-09	Boehringer Ingelheim Vetmedica Gmbh	Prophylaxe und Behandlung von PRDC
EP1958644A1 (de)	2007-02-13	2008-08-20	Boehringer Ingelheim Vetmedica Gmbh	Vorbeugung und Behandlung von subklinischer PCVD
US7829274B2 (en)	2007-09-04	2010-11-09	Boehringer Ingelheim Vetmedica, Inc.	Reduction of concomitant infections in pigs by the use of PCV2 antigen
BRPI0907438A2 (pt) *	2008-01-23	2015-08-04	Boehringer Ingelheim Vetmed	Composições imunogênicas para mycoplasma hyopneumoniae e pcv2 e métodos para produzir tais composições
AR078253A1 (es)	2009-09-02	2011-10-26	Boehringer Ingelheim Vetmed	Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
AR084358A1 (es)	2010-12-27	2013-05-08	Lilly Co Eli	Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
EP2658570B1 (de) *	2010-12-27	2018-11-28	Elanco US Inc.	Impfstoffzusammensetzung gegen virus der viralen rinderdiarrhoe und verwendung
UA114503C2 (uk)	2012-04-04	2017-06-26	Зоетіс Сервісіз Ллс	Комбінована вакцина pcv та mycoplasma hyopneumoniae
US9120859B2 (en)	2012-04-04	2015-09-01	Zoetis Services Llc	Mycoplasma hyopneumoniae vaccine
UA114504C2 (uk)	2012-04-04	2017-06-26	Зоетіс Сервісіз Ллс	Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
PL2994162T3 (pl)	2013-05-08	2021-10-18	Pharmgate Biologics Inc.	Szczepionka przeciwko pcv2 i mykoplazmie
CA2925281C (en)	2013-09-25	2022-05-03	Zoetis Services Llc	Pcv2b divergent vaccine composition and methods of use
ES2778425T3 (es)	2013-10-02	2020-08-10	Boehringer Ingelheim Animal Health Usa Inc	Variante de la proteína ORF2 del PCV2 y partículas similares a virus compuestas por esta
US20210290754A1 (en) *	2018-08-07	2021-09-23	Wisconsin Alumni Research Foundation (Warf)	Recombinant biologically contained filovirus vaccine
WO2020163804A1 (en)	2019-02-08	2020-08-13	Wisconsin Alumni Research Foundation (Warf)	Humanized cell line
WO2021041624A2 (en)	2019-08-27	2021-03-04	Yoshihiro Kawaoka	Recombinant influenza viruses with stabilized ha for replication in eggs
CA3157405A1 (en) *	2019-11-18	2021-05-27	Donald D. EVANS II	Lyophilized cake in straight-walled vial

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NL8301996A (nl) *	1983-06-06	1985-01-02	Duphar Int Res	Werkwijze ter bereiding van geadjuveerde levende vaccins en aldus verkregen geadjuveerde levende vaccins.
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US4606918A (en) *	1983-08-22	1986-08-19	Syntex (U.S.A.) Inc.	Polyoxypropylene-polyoxyethylene block polymer based adjuvants
ATE365049T1 (de) *	1994-05-10	2007-07-15	Wyeth Corp	Abgeänderter, verbesserter brsv lebend- impfstoff

1995
- 1995-05-08 AT AT99115633T patent/ATE365049T1/de active
- 1995-05-08 EP EP99115633A patent/EP0968722B1/de not_active Expired - Lifetime
- 1995-05-08 ES ES07008378T patent/ES2429401T3/es not_active Expired - Lifetime
- 1995-05-08 EP EP07008378.7A patent/EP1820512B1/de not_active Expired - Lifetime
- 1995-05-08 EP EP07007405A patent/EP1844791A1/de not_active Withdrawn
- 1995-05-08 CA CA2189979A patent/CA2189979C/en not_active Expired - Lifetime
- 1995-05-08 PT PT70083787T patent/PT1820512E/pt unknown
- 1995-05-08 EP EP95918442A patent/EP0759780B1/de not_active Expired - Lifetime
- 1995-05-08 DE DE69518316T patent/DE69518316T2/de not_active Expired - Lifetime
- 1995-05-08 NZ NZ285324A patent/NZ285324A/en not_active IP Right Cessation
- 1995-05-08 ES ES95918442T patent/ES2149361T3/es not_active Expired - Lifetime
- 1995-05-08 MY MYPI95001214A patent/MY111829A/en unknown
- 1995-05-08 DE DE69535520T patent/DE69535520T2/de not_active Expired - Lifetime
- 1995-05-08 ZA ZA953703A patent/ZA953703B/xx unknown
- 1995-05-08 PT PT95918442T patent/PT759780E/pt unknown
- 1995-05-08 AU AU24387/95A patent/AU711350B2/en not_active Expired
- 1995-05-08 DK DK99115633T patent/DK0968722T3/da active
- 1995-05-08 JP JP52920895A patent/JP3993230B2/ja not_active Expired - Lifetime
- 1995-05-08 SI SI9530374T patent/SI0759780T1/xx unknown
- 1995-05-08 DK DK95918442T patent/DK0759780T3/da active
- 1995-05-08 PT PT99115633T patent/PT968722E/pt unknown
- 1995-05-08 KR KR1019960706404A patent/KR100374434B1/ko not_active IP Right Cessation
- 1995-05-08 WO PCT/US1995/006053 patent/WO1995030437A1/en active IP Right Grant
- 1995-05-08 ES ES99115633T patent/ES2287997T3/es not_active Expired - Lifetime
- 1995-05-08 CN CNB951939424A patent/CN1268393C/zh not_active Expired - Lifetime
- 1995-05-08 BR BR9507717A patent/BR9507717A/pt not_active IP Right Cessation
- 1995-05-08 AT AT95918442T patent/ATE195255T1/de active
- 1995-05-08 SI SI9530731T patent/SI0968722T1/sl unknown
1996
- 1996-04-25 US US08/638,879 patent/US5733555A/en not_active Expired - Lifetime
1997
- 1997-12-18 US US08/993,400 patent/US5958423A/en not_active Expired - Lifetime
2000
- 2000-06-21 HK HK00103769A patent/HK1024412A1/xx not_active IP Right Cessation
- 2000-09-13 GR GR20000402092T patent/GR3034402T3/el unknown
2007
- 2007-03-07 JP JP2007057402A patent/JP2007137905A/ja not_active Withdrawn
2011
- 2011-08-26 JP JP2011184908A patent/JP2011246489A/ja active Pending

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Publication number	Publication date
JP3993230B2 (ja)	2007-10-17
EP0968722B1 (de)	2007-06-20
WO1995030437A1 (en)	1995-11-16
US5958423A (en)	1999-09-28
HK1024412A1 (en)	2000-10-13
US5733555A (en)	1998-03-31
CA2189979C (en)	2011-04-19
DK0759780T3 (da)	2000-11-13
DE69518316T2 (de)	2001-03-29
EP1820512B1 (de)	2013-07-03
ZA953703B (en)	1996-01-10
PT1820512E (pt)	2013-10-09
MY111829A (en)	2001-01-31
PT759780E (pt)	2001-01-31
EP1820512A1 (de)	2007-08-22
EP0759780A1 (de)	1997-03-05
ATE365049T1 (de)	2007-07-15
DE69518316D1 (de)	2000-09-14
CA2189979A1 (en)	1995-11-16
PT968722E (pt)	2007-09-06
NZ285324A (en)	1998-08-26
ES2429401T3 (es)	2013-11-14
KR100374434B1 (ko)	2003-06-09
DK0968722T3 (da)	2007-09-24
EP1844791A1 (de)	2007-10-17
CN1152878A (zh)	1997-06-25
ES2149361T3 (es)	2000-11-01
KR970703166A (ko)	1997-07-03
DE69535520T2 (de)	2008-02-07
EP0759780B1 (de)	2000-08-09
DE69535520D1 (de)	2007-08-02
CN1268393C (zh)	2006-08-09
JP2011246489A (ja)	2011-12-08
GR3034402T3 (en)	2000-12-29
SI0968722T1 (sl)	2007-10-31
JP2007137905A (ja)	2007-06-07
ES2287997T3 (es)	2007-12-16
SI0759780T1 (en)	2000-12-31
BR9507717A (pt)	1997-09-23
AU711350B2 (en)	1999-10-14
EP0968722A1 (de)	2000-01-05
AU2438795A (en)	1995-11-29
JPH10500113A (ja)	1998-01-06

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