[go: up one dir, main page]

ATE161291T1 - Verfahren und reagenzien zum nachweis von hepatitis c - Google Patents

Verfahren und reagenzien zum nachweis von hepatitis c

Info

Publication number
ATE161291T1
ATE161291T1 AT92114115T AT92114115T ATE161291T1 AT E161291 T1 ATE161291 T1 AT E161291T1 AT 92114115 T AT92114115 T AT 92114115T AT 92114115 T AT92114115 T AT 92114115T AT E161291 T1 ATE161291 T1 AT E161291T1
Authority
AT
Austria
Prior art keywords
nucleic acids
methods
detecting
amplifying
image
Prior art date
Application number
AT92114115T
Other languages
English (en)
Inventor
Robert M Resnick
Karen K Y Young
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27115393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE161291(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE161291T1 publication Critical patent/ATE161291T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/706Specific hybridization probes for hepatitis
    • C12Q1/707Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Paints Or Removers (AREA)
AT92114115T 1991-08-27 1992-08-19 Verfahren und reagenzien zum nachweis von hepatitis c ATE161291T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75130591A 1991-08-27 1991-08-27
US91884492A 1992-07-21 1992-07-21

Publications (1)

Publication Number Publication Date
ATE161291T1 true ATE161291T1 (de) 1998-01-15

Family

ID=27115393

Family Applications (2)

Application Number Title Priority Date Filing Date
AT92114115T ATE161291T1 (de) 1991-08-27 1992-08-19 Verfahren und reagenzien zum nachweis von hepatitis c
AT97106534T ATE241704T1 (de) 1991-08-27 1992-08-19 Primers und sondern zum nachweis von hepatitis c

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT97106534T ATE241704T1 (de) 1991-08-27 1992-08-19 Primers und sondern zum nachweis von hepatitis c

Country Status (18)

Country Link
US (2) US5527669A (de)
EP (2) EP0529493B1 (de)
JP (2) JP3790274B2 (de)
KR (1) KR100280758B1 (de)
CN (2) CN1047630C (de)
AT (2) ATE161291T1 (de)
AU (1) AU665952B2 (de)
CA (1) CA2076793C (de)
DE (2) DE69223562T2 (de)
DK (2) DK0529493T3 (de)
ES (2) ES2111589T3 (de)
FI (1) FI108731B (de)
GR (1) GR3026312T3 (de)
HK (1) HK1027868A1 (de)
IL (1) IL102896A (de)
NO (1) NO311730B1 (de)
NZ (1) NZ244071A (de)
PT (1) PT787807E (de)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639594A (en) * 1990-02-16 1997-06-17 United Biomedical, Inc. Linear and branched peptides effective in diagnosing and detecting non-A, non-B hepatitis
US5582968A (en) * 1990-02-16 1996-12-10 United Biomedical, Inc. Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis
US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
EP0967279B1 (de) * 1992-03-02 2008-01-02 Novartis Vaccines and Diagnostics S.r.l. Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und Diagnostik
EP0718400A3 (de) * 1992-09-28 1996-07-03 Chiron Corporation Verfahren und Zusammensetzungen zur Kontrolle der Überstetzung von HCV-Proteine
US7258977B1 (en) 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
ATE179459T1 (de) 1992-11-27 1999-05-15 Innogenetics Nv Verfahren zur typisierung von hcv-isolaten
ES2232815T5 (es) * 1993-05-10 2009-06-15 Novartis Vaccines And Diagnostics, Inc. Metodos de tipado del virus de la hepatitis c y reactivos para usar en los mismos.
DK0632134T3 (da) * 1993-07-01 2001-12-03 Hoffmann La Roche Reagenser og fremgangsmåder til koblet revers transkription ved høj temperatur og polymerase-kædereaktioner
US6558898B1 (en) 1994-02-14 2003-05-06 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US6156495A (en) * 1994-02-14 2000-12-05 Abbott Laboratories Hepatitis GB virus recombinant proteins and uses thereof
US5981172A (en) * 1994-02-14 1999-11-09 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E Hepatitis reagents and methods for their use
US6451578B1 (en) 1994-02-14 2002-09-17 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US6051374A (en) * 1994-02-14 2000-04-18 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US6720166B2 (en) 1994-02-14 2004-04-13 Abbott Laboratories Non-a, non-b, non-c, non-c, non-d, non-e hepatitis reagents and methods for their use
US6586568B1 (en) 1994-02-14 2003-07-01 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US5843450A (en) * 1994-02-14 1998-12-01 Abbott Laboratories Hepatitis GB Virus synthetic peptides and uses thereof
EP0769018B1 (de) * 1994-07-01 2002-12-18 Chiron Corporation Helicobacter proteine und impstoffe
US5807670A (en) * 1995-08-14 1998-09-15 Abbott Laboratories Detection of hepatitis GB virus genotypes
US5955318A (en) * 1995-08-14 1999-09-21 Abbott Laboratories Reagents and methods useful for controlling the translation of hepatitis GBV proteins
US6127116A (en) * 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
US7235394B1 (en) 1995-08-29 2007-06-26 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
US5837442A (en) 1995-11-29 1998-11-17 Roche Molecular Systems, Inc. Oligonucleotide primers for amplifying HCV nucleic acid
WO1997025429A1 (en) * 1996-01-04 1997-07-17 Rican Limited Helicobacter pylori bacterioferritin
US5759795A (en) * 1996-03-08 1998-06-02 Schering Corporation Assay for determining inhibitors of ATPase
IT1284847B1 (it) * 1996-06-07 1998-05-22 Sorin Biomedica Diagnostics Sp Procedimento per la rivelazione di acidi nucleici specifici di hcv
US5989873A (en) * 1996-09-24 1999-11-23 Vinayagamoorthy; Thuraiayah Method of detecting gene expression and/or of preventing such expression in cells
CU22642A1 (es) * 1996-12-12 2000-12-22 Ct Ingenieria Genetica Biotech Secuencia de adnc derivadas del genoma del virus de la hepatitis c y su uso
US7049428B1 (en) * 1998-03-04 2006-05-23 Washington University HCV variants
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
US5849800A (en) * 1997-03-28 1998-12-15 The Penn State Research Foundation Use of amantadine for treatment of Hepatitis C
US6277571B1 (en) * 1997-10-03 2001-08-21 Virginia Commonwealth University Intellectual Property Foundation Sequential consensus region-directed amplification of known and novel members of gene families
EP1029083A2 (de) 1997-11-04 2000-08-23 Roche Diagnostics GmbH Spezifisches und sensitives nukleinsäurenachweisverfahren
DE19832050C2 (de) * 1998-07-16 2002-10-10 Biotest Pharma Gmbh Verfahren zum Nachweis von Hepatitis B- bzw. Hepatitis C-Virusgenomen in Plasmaproben und spezifische Primer
CA2245039A1 (en) * 1998-08-13 2000-02-13 Vito Scalia Primer-specific and mispair extension assay for identifying gene variation
US6300069B1 (en) * 1999-05-03 2001-10-09 Qiagen Gmbh Generation and amplification of nucleic acids from ribonucleic acids
CA2392218A1 (en) * 1999-11-17 2001-05-25 Jiuping Ji Simultaneous detection of hbv, hcv and hiv in plasma samples using a multiplex capture assay
KR20020063123A (ko) * 2001-01-26 2002-08-01 (주)네오딘 알티 피시알에 의한 c형 간염바이러스 검출을 위한 키트및 그 검출방법
US6586584B2 (en) 2001-01-29 2003-07-01 Becton, Dickinson And Company Sequences and methods for detection of Hepatitis C virus
US7718354B2 (en) 2001-03-02 2010-05-18 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US20040121311A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in livestock
AU2002311897A1 (en) * 2001-05-09 2002-11-18 Third Wave Technologies, Inc. Nucleic acid detection in pooled samples
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8073627B2 (en) * 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
US20050175629A1 (en) * 2001-08-31 2005-08-11 Giuseppe Del Giudice Helicobacter pylori vaccination
US7196183B2 (en) 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
US6946245B2 (en) 2001-12-04 2005-09-20 Quest Diagnostics Investments Incorporated Oligonucleotides and methods for detecting hepatitis C viral nucleic acids
GB0200526D0 (en) * 2002-01-11 2002-02-27 Science And Technology The Methods
CA2489895A1 (en) * 2002-07-26 2004-02-05 Abbott Laboratories Method of detecting and quantifying hepatitis c virus
US20040024193A1 (en) * 2002-07-26 2004-02-05 Williams Gregg T. Method of detecting and quantifying hepatitis C virus
US7820030B2 (en) * 2003-04-16 2010-10-26 Handylab, Inc. System and method for electrochemical detection of biological compounds
US8046171B2 (en) 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US7947450B2 (en) 2003-07-10 2011-05-24 Universite Libre De Bruxelles Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed
US7700276B2 (en) * 2003-07-10 2010-04-20 Universite Libre De Bruxelles Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed
ES2596753T3 (es) 2003-08-29 2017-01-11 Fujirebio Europe N.V. Nuevo clado del virus de la hepatitis C y secuencias prototipo del mismo
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US20120122103A1 (en) 2003-09-11 2012-05-17 Rangarajan Sampath Compositions for use in identification of bacteria
TWI375679B (en) * 2003-10-14 2012-11-01 Hoffmann La Roche Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
US8163895B2 (en) 2003-12-05 2012-04-24 Ibis Biosciences, Inc. Compositions for use in identification of orthopoxviruses
US7473773B2 (en) * 2004-01-07 2009-01-06 Third Wave Technologies, Inc. Determination of hepatitis C virus genotype
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
CA2567839C (en) 2004-05-24 2011-06-28 Isis Pharmaceuticals, Inc. Mass spectrometry with selective ion filtration by digital thresholding
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
US20060068396A1 (en) * 2004-09-24 2006-03-30 Kaohsiung Medical University Method for biochip detecting limited cells
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
CA2600184A1 (en) 2005-03-03 2006-09-08 Isis Pharmaceuticals, Inc. Compositions for use in identification of adventitious viruses
US7919242B2 (en) * 2005-06-30 2011-04-05 Roche Molecular Systems, Inc. Light emission modifiers and their uses in nucleic acid detection, amplification and analysis
AU2006272776B2 (en) 2005-07-21 2012-01-19 Ibis Biosciences, Inc. Methods for rapid identification and quantitation of nucleic acid variants
US20090050492A1 (en) * 2005-08-02 2009-02-26 Board Of Trustees Of Michigan State University Nanoporous silicon-based electrochemical nucleic acid biosensor
EP2064332B1 (de) 2006-09-14 2012-07-18 Ibis Biosciences, Inc. Gezielte gesamtgenomamplifizierung zur identifizierung von krankheitserregern
WO2008104002A2 (en) 2007-02-23 2008-08-28 Ibis Biosciences, Inc. Methods for rapid forensic dna analysis
US20100291544A1 (en) * 2007-05-25 2010-11-18 Ibis Biosciences, Inc. Compositions for use in identification of strains of hepatitis c virus
WO2008151023A2 (en) 2007-06-01 2008-12-11 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
EP2344893B1 (de) 2008-09-16 2014-10-15 Ibis Biosciences, Inc. Mikroplatten-handhabungssysteme und verfahren
US8148163B2 (en) 2008-09-16 2012-04-03 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
US8550694B2 (en) 2008-09-16 2013-10-08 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
WO2010090857A2 (en) 2009-01-21 2010-08-12 Vertex Pharmaceuticals Incorporated Methods for amplifying hepatitis c virus nucleic acids
US8158936B2 (en) 2009-02-12 2012-04-17 Ibis Biosciences, Inc. Ionization probe assemblies
WO2011008971A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Lift and mount apparatus
WO2011008972A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systems for bioagent identification
ES2628739T3 (es) 2009-10-15 2017-08-03 Ibis Biosciences, Inc. Amplificación por desplazamiento múltiple
EP2707496A1 (de) 2011-05-11 2014-03-19 Diagon Kft. Verfahren zur schnellen bestimmung von viren mittels nukleinsäurebasierter molekulardiagnostik und kit hierfür
US9422601B2 (en) 2011-12-15 2016-08-23 Samsung Electronics Co., Ltd. Method of determining a ratio of RNA species in a sample
EP2722398B1 (de) 2012-10-18 2017-07-12 F. Hoffmann-La Roche AG Test mit zwei Sonden zur Erkennung von HCV
EP2722397B1 (de) * 2012-10-18 2017-12-13 F. Hoffmann-La Roche AG Test mit zwei Sonden zur Erkennung von heterogenen Amplikonpopulationen
CN105483283B (zh) * 2014-10-11 2019-01-18 上海仁度生物科技有限公司 丙型肝炎病毒hcv实时荧光核酸恒温扩增检测试剂盒
EP3469102B1 (de) 2016-06-10 2023-01-25 Roche Diagnostics GmbH Zusammensetzungen und verfahren zur detektion von hepatitis-c-virus-genotyp 3
CN108018376B (zh) * 2016-10-31 2020-11-03 深圳华大因源医药科技有限公司 一种用于丙肝病毒分型和耐药位点检测的探针和方法
CA3068482A1 (en) * 2017-10-03 2019-04-11 Abbott Molecular Inc. Assay for detecting hepatitis c virus (hcv)
GB201819726D0 (en) * 2018-12-03 2019-01-16 Diagnostics For The Real World Ltd HCV detection

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DE318216T1 (de) * 1987-11-18 1990-06-13 Chiron Corp., Emeryville, Calif. Nanbv-diagnostika und vakzine.
UA50829C2 (uk) * 1989-03-17 2002-11-15 Чірон Корпорейшн Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл
JP2656996B2 (ja) * 1989-05-18 1997-09-24 カイロン コーポレイション Nanbvの診断用薬
DE4023458A1 (de) * 1989-08-31 1991-03-07 Kali Chemie Ag Neue hochalkalische proteasen
JP3156200B2 (ja) * 1989-09-15 2001-04-16 国立予防衛生研究所長 新規のhcv分離株
BR9006422A (pt) * 1989-12-18 1991-09-24 Wellcome Found Processo para preparar um polipeptidio viral pt-nanbh e processo para detectar o mesmo
ATE151112T1 (de) * 1989-12-22 1997-04-15 Hoffmann La Roche Bei hoher temperatur aktive reverse transkriptasen
CA2044296A1 (en) * 1990-06-12 1991-12-13 Hiroaki Okamoto Oligonucleotide primers, and their application for high-fidelity detection of non-a, non-b hepatitis virus
EP0933426A1 (de) * 1990-06-25 1999-08-04 The Research Foundation for Microbial Diseases of Osaka University Non-A, Non-B Hepatitis Virus genomisches DNS und Antigenpolypeptide
EP0468657A3 (en) * 1990-07-09 1992-02-05 Tonen Corporation Non-a non b hepatitis-specific antigen and its use in hepatitus diagnosis
DK0469348T3 (da) * 1990-07-11 1997-04-01 Shionogi & Co cDNA-sekvens og detektering af hepatitis C-virus
JP2714255B2 (ja) * 1990-08-10 1998-02-16 カイロン コーポレイション Nanbv診断法:c型肝炎ウイルスのスクリーニングに有用なポリヌクレオチド
KR930702365A (ko) * 1990-08-25 1993-09-08 존 더블유. 아담슨 비-a형, 비-b형 간염 바이러스 항원, 진단 방법 및 백신
EP0485209A1 (de) * 1990-11-08 1992-05-13 Immuno Japan Inc. Mit Non-A Non-B Hepatitis Virus verwandtes Antigen, Aufspürsysteme für Antikörper, Polynukleotide und Polypeptide

Also Published As

Publication number Publication date
NO923341D0 (no) 1992-08-26
EP0529493A2 (de) 1993-03-03
AU2121992A (en) 1993-03-04
DK0787807T3 (da) 2003-08-11
FI108731B (fi) 2002-03-15
DE69223562T2 (de) 1998-06-04
CN1259670A (zh) 2000-07-12
EP0529493B1 (de) 1997-12-17
DE69233083D1 (de) 2003-07-03
NO311730B1 (no) 2002-01-14
GR3026312T3 (en) 1998-06-30
HK1027868A1 (en) 2001-01-23
JPH0686700A (ja) 1994-03-29
JP4164098B2 (ja) 2008-10-08
EP0529493A3 (en) 1993-07-28
PT787807E (pt) 2003-08-29
CA2076793A1 (en) 1993-02-28
NZ244071A (en) 1995-01-27
DK0529493T3 (da) 1998-08-24
CN1071512A (zh) 1993-04-28
JP2006180884A (ja) 2006-07-13
JP3790274B2 (ja) 2006-06-28
ES2198514T3 (es) 2004-02-01
CA2076793C (en) 2006-11-21
US5580718A (en) 1996-12-03
US5527669A (en) 1996-06-18
EP0787807A3 (de) 1998-04-01
FI923840A0 (fi) 1992-08-27
ATE241704T1 (de) 2003-06-15
DE69223562D1 (de) 1998-01-29
AU665952B2 (en) 1996-01-25
CN1047630C (zh) 1999-12-22
IL102896A (en) 1997-11-20
FI923840L (fi) 1993-02-28
EP0787807B1 (de) 2003-05-28
NO923341L (no) 1993-03-01
KR100280758B1 (ko) 2001-04-02
ES2111589T3 (es) 1998-03-16
EP0787807A2 (de) 1997-08-06
KR930004479A (en) 1993-03-22
IL102896A0 (en) 1993-01-31
DE69233083T2 (de) 2003-12-18
CN1134666C (zh) 2004-01-14

Similar Documents

Publication Publication Date Title
ATE161291T1 (de) Verfahren und reagenzien zum nachweis von hepatitis c
ATE220726T1 (de) Oligonukleotid-primer für amplifizierung von hcv- nukleinsäure
DE69627408D1 (de) Primers und Sonden zum Nachweis von HIV
DE69518697D1 (de) Nachweis von Treponema Pallidum und Haemophilus Ducreyi
DE69121821D1 (de) Nukleotid-Sequenzen nützlich als typenspezifische Sonden, PCR Primers und LCR Sonden zur Amplifikation und zum Nachweis von humanem Papillomavirus, sowie dazu verwendete Kits und Verfahren
KR950701392A (ko) 인체 B형 간염 바이러스에 대한 핵산 증폭 올리고뉴클레오티드 및 프로브(Nucleic Acide Amplification Oligonucleotides and Probes to Human Hepatitis B Birus)
KR930008138A (ko) 특정한 뉴클레오티드 시퀀스를 포함하는 약독화(弱毒化)된 홍역 백신 바이러스 균주와 그의 완벽한 동정 방법
ATE449194T1 (de) Oligonukleotide zur detektion von hepatitis b viren
SE9002060D0 (sv) A method of detecting an infection caused by a specific type of virus, primers, probes and a test kit
ATE455864T1 (de) Verfahren zum nachweis von in einer polymerase- kettenreaktion amplifizierten nukleinsäuremolekülen
DE69610933D1 (de) Verfahren und reagenzien zur typisierung von hla-genen der klasse i
DE60015210D1 (de) Oligonukleotid Primer zur effizienten reversen Transkription von Hepatitis C Virus (HCV) RNS und Verfahren zu deren Verwendung
WO2001029248A3 (en) Method for amplifying and detecting nucleic acid
RU93013954A (ru) Способ обнаружения вируса иммунодефицита