[go: up one dir, main page]

ATE131176T1 - Sulfatierte polysaccharide, antikoagulierungs- und antikomplementärmittel, hergestellt aus fukanen aus braunen algen, und verfahren zu deren herstellung. - Google Patents

Sulfatierte polysaccharide, antikoagulierungs- und antikomplementärmittel, hergestellt aus fukanen aus braunen algen, und verfahren zu deren herstellung.

Info

Publication number
ATE131176T1
ATE131176T1 AT90401636T AT90401636T ATE131176T1 AT E131176 T1 ATE131176 T1 AT E131176T1 AT 90401636 T AT90401636 T AT 90401636T AT 90401636 T AT90401636 T AT 90401636T AT E131176 T1 ATE131176 T1 AT E131176T1
Authority
AT
Austria
Prior art keywords
fucanes
anticomplmentary
anticoagulation
production
brown algae
Prior art date
Application number
AT90401636T
Other languages
English (en)
Inventor
Sylvia Colliec
Jacqueline Bretaudiere
Patrick Durand
Anne-Marie Fischer
Jacqueline Jozefonvicz
Bernard Kloareg
Catherine Vidal
Original Assignee
Ifremer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ifremer filed Critical Ifremer
Application granted granted Critical
Publication of ATE131176T1 publication Critical patent/ATE131176T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Control Or Security For Electrophotography (AREA)
  • Storing Facsimile Image Data (AREA)
  • Editing Of Facsimile Originals (AREA)
  • Dot-Matrix Printers And Others (AREA)
  • Counters In Electrophotography And Two-Sided Copying (AREA)
  • Cultivation Of Seaweed (AREA)
AT90401636T 1989-06-14 1990-06-13 Sulfatierte polysaccharide, antikoagulierungs- und antikomplementärmittel, hergestellt aus fukanen aus braunen algen, und verfahren zu deren herstellung. ATE131176T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8907857A FR2648463B1 (fr) 1989-06-14 1989-06-14 Polysaccharides sulfates, agent anticoagulant et agent anticomplementaire obtenus a partir de fucanes d'algues brunes et leur procede d'obtention

Publications (1)

Publication Number Publication Date
ATE131176T1 true ATE131176T1 (de) 1995-12-15

Family

ID=9382699

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90401636T ATE131176T1 (de) 1989-06-14 1990-06-13 Sulfatierte polysaccharide, antikoagulierungs- und antikomplementärmittel, hergestellt aus fukanen aus braunen algen, und verfahren zu deren herstellung.
AT95105774T ATE196089T1 (de) 1989-06-14 1990-06-13 Mittel zur hemmung des komplementsystems hergestellt aus fucanen aus braunen algen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT95105774T ATE196089T1 (de) 1989-06-14 1990-06-13 Mittel zur hemmung des komplementsystems hergestellt aus fucanen aus braunen algen

Country Status (13)

Country Link
US (1) US5321133A (de)
EP (2) EP0403377B1 (de)
JP (1) JP3042543B2 (de)
CN (1) CN1051564A (de)
AT (2) ATE131176T1 (de)
AU (1) AU5841090A (de)
DD (1) DD296937A5 (de)
DE (2) DE69033626T2 (de)
ES (1) ES2152998T3 (de)
FR (1) FR2648463B1 (de)
IE (1) IE902153A1 (de)
PT (1) PT94359A (de)
WO (1) WO1990015823A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1059679C (zh) * 1993-06-18 2000-12-20 青岛海洋大学 制备藻酸双酯钠的方法
DE69637747D1 (de) * 1995-04-28 2008-12-24 Res Inst For Glycotechnology H Zuckerverbindungen
FR2738009B1 (fr) * 1995-08-24 1997-10-31 Centre Nat Rech Scient Procede d'obtention de polysaccharides sulfates
JP3555766B2 (ja) * 1996-01-26 2004-08-18 タカラバイオ株式会社 アポトーシス誘発剤
EP0884383A4 (de) * 1996-02-29 2001-12-05 Takara Shuzo Co Methode zum reinigen und entfernen von viren.
IT1288713B1 (it) * 1996-12-18 1998-09-23 Crinos Industria Farmaco Fucani a basso peso molecolare aventi attivita' anticoagulante antitrombinica e antitrombotica
FR2772618B1 (fr) * 1997-12-18 2000-02-18 Ifremer Utilisation de fucane comme regulateur de la reconstruction des tissus conjonctifs
KR20010034137A (ko) * 1998-02-17 2001-04-25 오미야 히사시 설페이트화 사카라이드
FR2797768B1 (fr) * 1999-09-01 2003-06-13 Ifremer Utilisation d'un polysaccharide sulfate de bas poids moleculaire pour l'obtention d'un medicament actif contre la thrombose vasculaire
CN1108310C (zh) * 1999-11-30 2003-05-14 中国科学院南海海洋研究所 一种海藻多糖及其制备方法和用途
KR100369518B1 (ko) * 2000-02-02 2003-01-30 김공수 저분자 다당류의 제조방법
US20040136938A1 (en) * 2000-09-11 2004-07-15 Robert Ladislas Composition of vitamin c and/or vitamin a
US20040097464A1 (en) * 2000-09-11 2004-05-20 Ladislas Robert Mixture of non-sulfated fucose-based oligosaccharides, a cosmetic or pharmaceutical composition comprising said mixture and its use in cosmetics or pharmacy
US6812220B2 (en) * 2001-08-29 2004-11-02 University Of British Columbia Pharmaceutical compositions and methods relating to fucans
EP1306389B1 (de) * 2001-10-24 2004-12-29 Takara Bio Inc. Sulfatiertes Fucan Oligosaccharid
JP4262601B2 (ja) * 2002-01-18 2009-05-13 タカラバイオ株式会社 硫酸化フカン
US20040208893A1 (en) * 2002-12-16 2004-10-21 Daniels Bruce Alan Seaweed extract composition for treatment of diabetes and diabetic complications
US6797705B2 (en) * 2002-12-16 2004-09-28 Endomatrix, Inc. Rhamnan sulphate composition for treatment of endothelial dysfunction
JPWO2005095427A1 (ja) * 2004-04-02 2008-02-21 タカラバイオ株式会社 血栓症の予防又は治療のための組成物
FR2881051A1 (fr) * 2005-01-27 2006-07-28 Therapol Sa Utilisation de fucanes selectionnes pour la preparation d'un materiau bacteriophobe et bacteriostatique, materiau correspondant et applications
FR2882258B1 (fr) * 2005-02-22 2009-01-16 Oreal Utilisation capillaire de polysaccharides sulfates
KR100729638B1 (ko) 2005-05-20 2007-06-19 배태진 미역포자엽으로부터 분리한 항혈액응고활성을 가진황산화푸코스다당 및 그 제조방법
WO2007028256A2 (en) 2005-09-09 2007-03-15 Les Biotechnologies Oceanova Inc. Polysaccharides compositions comprising fucans and galactans and their use to reduce extravasation and inflammation
FR2897538B1 (fr) 2006-02-23 2008-05-02 Univ Paris Descartes Utilisation de fucanes a des fins de greffe, d'ingenierie et de regeneration osseuses
CN101168570B (zh) * 2007-11-15 2010-05-26 暨南大学 海带硫酸多糖的降解方法
JP4428486B1 (ja) * 2008-10-28 2010-03-10 国立大学法人鳥取大学 線溶賦活剤
WO2010086696A1 (en) * 2009-01-28 2010-08-05 Therapol Low-molecular-weight sulphated polysaccharides as candidates for anti-angiogenic therapy
EP3156078B1 (de) 2009-04-10 2020-03-04 INSERM (Institut National de la Santé et de la Recherche Médicale) Fucoidane als liganden zur diagnose degenerativer pathologien
CA2889934A1 (en) * 2012-10-29 2014-05-08 Matis Ohf. Use of natural antioxidants during enzymatic hydrolysis of aquatic protein to obtain high quality aquatic protein hydrolysates
WO2014147597A1 (en) 2013-03-21 2014-09-25 Institut National De La Sante Et De La Recherche Medicale Aminofucoidan as a vector for fibrinolysis in thrombotic diseases
FR3047179B1 (fr) * 2016-01-29 2019-10-25 Seprosys Ulvanes sulfates et utilisation dans la regulation des troubles de la coagulation
MX2020002288A (es) 2016-08-31 2020-07-14 Oji Holdings Corp Metodo de produccion para xilooligosacarido acido y xilooligosacarido acido.
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
FR3055549A1 (fr) * 2016-09-02 2018-03-09 Universite Blaise Pascal-Clermont-Ferrand Ii Polysaccharide sulfate extrait d'une algue rouge pour son utilisation en tant qu'anticoagulant
JP6281659B1 (ja) 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
SG11201911318SA (en) 2017-05-31 2020-01-30 Oji Holdings Corp Moisturizing topical preparation
KR102678054B1 (ko) 2017-09-12 2024-06-24 오지 홀딩스 가부시키가이샤 폴리황산펜토산 및 폴리황산펜토산의 제조 방법
HUE062342T2 (hu) 2017-12-20 2023-10-28 Oji Holdings Corp Pentozán-poliszulfát, valamint pentozán-poliszulfátot tartalmazó gyógyszerek
FR3079831B1 (fr) 2018-04-05 2020-11-20 Jymsea Procede d’extraction d’oligofucanes et ses applications
GB2579600B (en) 2018-12-05 2023-07-05 Byotrol Plc Anti-viral composition
CN110632188A (zh) * 2019-08-19 2019-12-31 中国石油天然气股份有限公司 酚醛凝胶含量的测试方法
WO2021249974A1 (en) 2020-06-09 2021-12-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Fucoidan-functionalized polysaccharide particles with t-pa for targeted thrombolytic therapy
FR3113236B1 (fr) 2020-08-05 2024-10-04 Algues Et Mer Fraction purifiée de fucoïdanes pour la préparation de compositions cosmétiques et/ou dermatologiques anti-age.
CN115386013B (zh) * 2022-04-19 2023-05-12 广西中医药大学 一种具有强效抗凝活性的海带多糖及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB890207A (en) * 1957-03-07 1962-02-28 Ciba Ltd Extraction of a new polysaccharide substance from crude fucoidin
US4098995A (en) * 1976-07-12 1978-07-04 American Cyanamid Company Polygalactosido-sucrose poly(h-)sulfate salts
FR2513122A1 (fr) * 1981-09-23 1983-03-25 Goemar Sa Nouveaux medicaments a base d'extraits d'algues, et formulations correspondantes

Also Published As

Publication number Publication date
EP0676207A2 (de) 1995-10-11
DE69033626D1 (de) 2000-10-12
FR2648463A1 (fr) 1990-12-21
DE69033626T2 (de) 2001-05-23
EP0676207A3 (de) 1995-11-08
DE69023957T2 (de) 1996-07-04
AU5841090A (en) 1991-01-08
JP3042543B2 (ja) 2000-05-15
PT94359A (pt) 1991-02-08
IE902153A1 (en) 1991-01-02
EP0676207B1 (de) 2000-09-06
WO1990015823A1 (fr) 1990-12-27
EP0403377B1 (de) 1995-12-06
FR2648463B1 (fr) 1993-01-22
DD296937A5 (de) 1991-12-19
EP0403377A1 (de) 1990-12-19
DE69023957D1 (de) 1996-01-18
JPH04506089A (ja) 1992-10-22
IE902153L (en) 1990-12-14
CN1051564A (zh) 1991-05-22
ATE196089T1 (de) 2000-09-15
US5321133A (en) 1994-06-14
ES2152998T3 (es) 2001-02-16

Similar Documents

Publication Publication Date Title
ATE131176T1 (de) Sulfatierte polysaccharide, antikoagulierungs- und antikomplementärmittel, hergestellt aus fukanen aus braunen algen, und verfahren zu deren herstellung.
SE9101957D0 (sv) Blandningar av polysackarider med laag molekylvikt samt framstaellning och anvaendning av desamma
MX22234A (es) Mejoras en composiciones de polimero y poliol, y el proceso para preparar polimero fenol-funcional.
DE69005394D1 (de) Zusammensetzungen welche komplexe von hyaluronsäure enthalten und verfahren zu deren herstellung.
DE69012154D1 (de) Heparinderivate und Verfahren zu ihrer Herstellung.
DE59005566D1 (de) Verfahren zur Herstellung von aktivierten Chitosanen und deren Verwendung bei der Herstellung von Chitosanderivaten.
ES2192560T3 (es) Material viscoelastico sintetico para aplicaciones oftalmicas.
FR2553287B1 (fr) Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire
IT1217658B (it) Processo perfezionato per la produzione di perfluoropolieteri costituiti sostanzialmente da unita' perfludossietilenche e perfluoroossipropileniche
IT8620939A0 (it) Processo per la preparazione di (2,2)-paraciclofano e suoi derivati.
ATE119547T1 (de) Oligosaccharide mit antiatherosclerotischer wirkung.
NZ222182A (en) A method for the modification of alginates for other uronic acid containing compounds to alter their functional properties
DE69019474D1 (de) Veschleissbeständige Polyoxymethylenharzzusammensetzung und Verfahren für ihre Herstellung.
AT374846B (de) Herzstueck, insbesondere herzstueckspitze, fuer schienenkreuzungen oder -weichen, sowie verfahren zu seiner herstellung
ITMI20000665A0 (it) Glicosaminoglicani derivati dal polisaccaride k5 aventi elevata attivita' anticoagulante ed antitrombotica e processo per la loro preparazio
IT8920929A0 (it) Nuovi derivati del r( ) 3 chinuclidinolo.
DE69313826D1 (de) Sulfatierte polysaccharide, verfahren zu deren herstellung, pharmazeutische zusammensetzung und ihre verwendung
ATA86690A (de) 2-substituierte n,n'-ditrimethoxybenzoylpiperazine, verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
DE3751162D1 (de) Verfahren zur Herstellung von Feinststrukturen in konjugierten Polymeren.
FR2645862B1 (fr) Derives d'isothiazolo-pyrydone azetidinyl substitues, leur preparation et leur application en tant que medicaments
EP0361490A3 (de) Oligosaccharid-Sulfate und ihre Derivate
DE69032707D1 (de) Genetische Kontrolle zur Acetylierung und Pyruvylierung von Xanthangummi
ATE118004T1 (de) 4-amidino-chroman und 4-amidino-pyrano(3,2- c)pyridinderivate, verfahren zur herstellung und diese enthaltende pharmazeutische zusammenstellungen.
IT8919524A0 (it) Derivati dal 1 arilsolfonil 2 piperidone, loro procedimento di preparazione e loro impiego come farmaci.
ATE156842T1 (de) Oligosaccharide mit biologischer aktivität und verfahren zur herstellung aus glykosaminoglykanen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties