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ATE119164T1 - Markierte modifizierte nukleotide und polynukleotide und verfahren zu deren herstellung, verwendung und detektion. - Google Patents

Markierte modifizierte nukleotide und polynukleotide und verfahren zu deren herstellung, verwendung und detektion.

Info

Publication number
ATE119164T1
ATE119164T1 AT88104961T AT88104961T ATE119164T1 AT E119164 T1 ATE119164 T1 AT E119164T1 AT 88104961 T AT88104961 T AT 88104961T AT 88104961 T AT88104961 T AT 88104961T AT E119164 T1 ATE119164 T1 AT E119164T1
Authority
AT
Austria
Prior art keywords
polynucleotides
detection
production
modified nucleotides
labeled modified
Prior art date
Application number
AT88104961T
Other languages
English (en)
Inventor
Dean Engelhardt
Elazar Rabbani
Stanley Kline
Jannis G Stavrianopoulos
Dollie Kirtikar
Original Assignee
Enzo Biochem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23546604&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE119164(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Enzo Biochem Inc filed Critical Enzo Biochem Inc
Application granted granted Critical
Publication of ATE119164T1 publication Critical patent/ATE119164T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT88104961T 1982-06-23 1983-06-22 Markierte modifizierte nukleotide und polynukleotide und verfahren zu deren herstellung, verwendung und detektion. ATE119164T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39144082A 1982-06-23 1982-06-23

Publications (1)

Publication Number Publication Date
ATE119164T1 true ATE119164T1 (de) 1995-03-15

Family

ID=23546604

Family Applications (3)

Application Number Title Priority Date Filing Date
AT83106112T ATE81342T1 (de) 1982-06-23 1983-06-22 Markierte modifizierte nucleotide und polynucleotide, verfahren zu ihrer herstellung, verwendung und aufspuerung.
AT88104963T ATE165605T1 (de) 1982-06-23 1983-06-22 Markierte modifizierte nucleotide und polynucleotide und verfahren zu deren herstellung, verwendung und nachweis
AT88104961T ATE119164T1 (de) 1982-06-23 1983-06-22 Markierte modifizierte nukleotide und polynukleotide und verfahren zu deren herstellung, verwendung und detektion.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT83106112T ATE81342T1 (de) 1982-06-23 1983-06-22 Markierte modifizierte nucleotide und polynucleotide, verfahren zu ihrer herstellung, verwendung und aufspuerung.
AT88104963T ATE165605T1 (de) 1982-06-23 1983-06-22 Markierte modifizierte nucleotide und polynucleotide und verfahren zu deren herstellung, verwendung und nachweis

Country Status (11)

Country Link
US (2) US8097405B1 (de)
EP (7) EP0097373B1 (de)
JP (4) JP2625095B2 (de)
AT (3) ATE81342T1 (de)
AU (2) AU585199B2 (de)
CA (1) CA1223831A (de)
DE (3) DE3382782T2 (de)
DK (1) DK291183A (de)
ES (4) ES8700270A1 (de)
IL (1) IL69051A (de)
NO (1) NO832292L (de)

Families Citing this family (209)

* Cited by examiner, † Cited by third party
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ATE81342T1 (de) 1992-10-15
AU4149389A (en) 1990-01-04
EP0285058A3 (de) 1990-09-26
EP0285057B1 (de) 1995-03-01
ES8700270A1 (es) 1986-09-16
EP0302175A2 (de) 1989-02-08
IL69051A (en) 1988-02-29
AU1617983A (en) 1984-01-05
ATE165605T1 (de) 1998-05-15
AU585199B2 (en) 1989-06-15
JP3170235B2 (ja) 2001-05-28
EP0097373A3 (en) 1984-06-06
EP0285057A2 (de) 1988-10-05
US8097405B1 (en) 2012-01-17
JPH11292892A (ja) 1999-10-26
EP0618228A1 (de) 1994-10-05
DK291183D0 (da) 1983-06-23
JPH06234787A (ja) 1994-08-23
EP0097373A2 (de) 1984-01-04
DE3382822D1 (de) 1998-06-04
JP2760466B2 (ja) 1998-05-28
EP0286898A3 (de) 1990-08-08
EP0285950A2 (de) 1988-10-12
DE3382626T2 (de) 1993-05-06
ES547320A0 (es) 1986-03-16
NO832292L (no) 1983-12-27
EP0285057A3 (en) 1990-10-31
ES8700324A1 (es) 1986-10-01
DE3382822T2 (de) 1998-11-19
DE3382782T2 (de) 1995-10-19
ES8606903A1 (es) 1986-03-16
ES547319A0 (es) 1988-04-16
JPH10158294A (ja) 1998-06-16
DE3382782D1 (de) 1995-04-06
CA1223831A (en) 1987-07-07
ES8802257A1 (es) 1988-04-16
EP0285950A3 (de) 1990-11-07
EP0286898A2 (de) 1988-10-19
ES523503A0 (es) 1986-09-16
DK291183A (da) 1983-12-24
EP0286898B1 (de) 1998-04-29
JP2625095B2 (ja) 1997-06-25
JPS5962600A (ja) 1984-04-10
US6992180B1 (en) 2006-01-31
IL69051A0 (en) 1983-10-31
ES539316A0 (es) 1986-10-01
EP0302175A3 (de) 1990-10-31
EP0285058A2 (de) 1988-10-05
DE3382626D1 (de) 1992-11-12
EP0097373B1 (de) 1992-10-07

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