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ATE107502T1 - Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens. - Google Patents

Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.

Info

Publication number
ATE107502T1
ATE107502T1 AT89911219T AT89911219T ATE107502T1 AT E107502 T1 ATE107502 T1 AT E107502T1 AT 89911219 T AT89911219 T AT 89911219T AT 89911219 T AT89911219 T AT 89911219T AT E107502 T1 ATE107502 T1 AT E107502T1
Authority
AT
Austria
Prior art keywords
stability during
improved stability
during drying
preparing liposomes
liposomes
Prior art date
Application number
AT89911219T
Other languages
English (en)
Inventor
Paul Gardner Schmidt
Gary Fujii
Original Assignee
Vestar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Inc filed Critical Vestar Inc
Application granted granted Critical
Publication of ATE107502T1 publication Critical patent/ATE107502T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Cosmetics (AREA)
AT89911219T 1988-10-05 1989-10-03 Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens. ATE107502T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25368088A 1988-10-05 1988-10-05

Publications (1)

Publication Number Publication Date
ATE107502T1 true ATE107502T1 (de) 1994-07-15

Family

ID=22961272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89911219T ATE107502T1 (de) 1988-10-05 1989-10-03 Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.

Country Status (13)

Country Link
US (1) US5817334A (de)
EP (1) EP0437479B1 (de)
JP (1) JP2792702B2 (de)
AT (1) ATE107502T1 (de)
AU (1) AU612285B2 (de)
CA (1) CA2000219A1 (de)
DE (1) DE68916439T2 (de)
DK (1) DK59691A (de)
FI (1) FI902249A0 (de)
IE (1) IE64559B1 (de)
IL (1) IL91901A (de)
NO (1) NO180363C (de)
WO (1) WO1990003795A1 (de)

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US6576460B1 (en) 1999-10-28 2003-06-10 Cornell Research Foundation, Inc. Filtration-detection device and method of use
JPWO2002038128A1 (ja) * 2000-11-10 2004-03-11 科学技術振興事業団 小胞体分散液の製造方法
US7125568B2 (en) * 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
JP4555569B2 (ja) * 2001-11-13 2010-10-06 セレーター ファーマシューティカルズ， インコーポレイテッド 増強された血中安定性を有する脂質キャリア組成物
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DE10233632A1 (de) * 2002-07-24 2004-02-05 Wilex Ag Formulierungen von Phenylalanin-Derivaten
AU2003268087A1 (en) * 2002-08-23 2004-03-11 Ian Ma Liposomal gemcitabine compositions for better drug delivery
EP1585504A4 (de) * 2002-11-06 2009-07-15 Azaya Therapeutics Inc Proteinstabilisierte liposomale formulierungen pharmazeutischer wirkstoffe
WO2004060363A1 (en) * 2002-12-23 2004-07-22 Vical Incorporated Method for producing sterile polynucleotide based medicaments
WO2004060059A2 (en) 2002-12-23 2004-07-22 Vical Incorporated Method for freeze-drying nucleic acid/block copolymer/cationic surfactant complexes
US20060223050A1 (en) * 2003-08-06 2006-10-05 The Regents Of The University Of California Office Of Technology Transfer Therapeutic platelets and methods
CA2566559C (en) * 2004-05-17 2014-05-06 Inex Pharmaceuticals Corporation Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof
FR2870741B1 (fr) * 2004-05-25 2008-03-14 Coletica Sa Phase lamellaires hydratees ou liposomes, contenant une monoamine grasse ou un polymere cationique favorisant la penetration intercellulaire, et composition cosmetique ou pharmaceutique la contenant.
AU2005302255A1 (en) * 2004-10-28 2006-05-11 Alza Corporation Lyophilized liposome formulations and method
WO2006068759A2 (en) * 2004-11-22 2006-06-29 Magellan Companies, Inc. Liposomes containing phytochemical agents and methods for making and using same
EP1932517A3 (de) * 2006-12-11 2008-07-16 Universiteit Utrecht Holding B.V. Liposomen beinhaltend Polyphenolderivaten und deren Verfahren zur Nachbeladung
US20090047336A1 (en) * 2007-08-17 2009-02-19 Hong Kong Baptist University novel formulation of dehydrated lipid vesicles for controlled release of active pharmaceutical ingredient via inhalation
US8962015B2 (en) * 2007-09-28 2015-02-24 Sdg, Inc. Orally bioavailable lipid-based constructs
CN101485629B (zh) * 2008-01-16 2013-01-23 沈阳药科大学 一种给药系统及其制备方法
WO2010010985A1 (en) * 2008-07-24 2010-01-28 Amorepacific Corporation Multi-layered lamellar granule and skin external application composition containing same
WO2010104883A1 (en) * 2009-03-09 2010-09-16 Molecular Express, Inc. Methods and compositions for liposomal formulation of antigens and uses thereof
US9775819B2 (en) * 2009-09-16 2017-10-03 R.P. Scherer Technologies, Llc Oral solid dosage form containing nanoparticles and process of formulating the same using fish gelatin
EP2386647A1 (de) * 2010-05-10 2011-11-16 Qiagen GmbH Verfahren zur Transfektion einer eurkaryotischen Zelle
EP2471511A1 (de) 2011-01-04 2012-07-04 Archivel Farma, SL Zur Behandlung oder Vorbeugung von Tuberkulose geeignete Liposomformulierung
PT2768484T (pt) 2011-10-21 2019-10-28 Jazz Pharmaceuticals Res Llc Lipossomas liofilizados
US10076496B2 (en) * 2011-11-11 2018-09-18 The Chinese University Of Hong Kong Engineering of polymer-stabilized nanoparticles for drugs with Log P values below 6 by controlled antisolvent precipitation
EA022183B1 (ru) * 2012-12-24 2015-11-30 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы цитохрома с
US11471401B2 (en) 2014-08-28 2022-10-18 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
US11504322B2 (en) 2014-08-28 2022-11-22 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
DK3185876T3 (da) 2014-08-28 2022-10-31 Massachusetts Gen Hospital Sammensætninger og fremgangsmåder til behandling af neurologiske lidelser
SG10201913504XA (en) 2016-02-26 2020-03-30 Massachusetts Gen Hospital Medical ice slurry production and delivery systems and methods
WO2021016457A1 (en) * 2019-07-24 2021-01-28 The General Hospital Corporation Methods of creating a substance with different freezing points by encapsulation
CN114886785B (zh) * 2022-06-07 2023-02-03 美尚(广州)化妆品股份有限公司 一种三元冻干组合物及其在冻干制剂中的应用

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Also Published As

Publication number Publication date
DK59691D0 (da) 1991-04-04
AU612285B2 (en) 1991-07-04
AU4340089A (en) 1990-05-01
DE68916439T2 (de) 1994-10-20
FI902249A0 (fi) 1990-05-04
IE64559B1 (en) 1995-08-23
NO180363C (no) 1997-04-09
DE68916439D1 (de) 1994-07-28
JPH04500803A (ja) 1992-02-13
CA2000219A1 (en) 1990-04-05
NO901852L (no) 1990-08-01
NO180363B (no) 1996-12-30
EP0437479B1 (de) 1994-06-22
JP2792702B2 (ja) 1998-09-03
IE893196L (en) 1990-04-05
WO1990003795A1 (en) 1990-04-19
US5817334A (en) 1998-10-06
IL91901A0 (en) 1990-06-10
DK59691A (da) 1991-04-04
NO901852D0 (no) 1990-04-26
EP0437479A1 (de) 1991-07-24
EP0437479A4 (en) 1991-10-16
IL91901A (en) 1993-06-10

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee