[go: up one dir, main page]

AR104050A1 - Proceso de producción con iones de cobre controlados - Google Patents

Proceso de producción con iones de cobre controlados

Info

Publication number
AR104050A1
AR104050A1 ARP160100777A ARP160100777A AR104050A1 AR 104050 A1 AR104050 A1 AR 104050A1 AR P160100777 A ARP160100777 A AR P160100777A AR P160100777 A ARP160100777 A AR P160100777A AR 104050 A1 AR104050 A1 AR 104050A1
Authority
AR
Argentina
Prior art keywords
medium
initial medium
production process
desired protein
initial
Prior art date
Application number
ARP160100777A
Other languages
English (en)
Inventor
Terashima Isamu
Doi Hiroyuki
Yamamoto Seiko
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of AR104050A1 publication Critical patent/AR104050A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Reivindicación 1: Un método de cultivo celular caracterizado porque comprende añadir un medio para siembra que contiene células a un medio inicial y comenzar a cultivar la célula en el medio inicial, en donde el medio inicial tiene un aditivo de medio de cultivo obtenido de organismos añadido al mismo y el .contenido de cobre del medio inicial al inicio del cultivo de células no es más que 0,02 ppm. Reivindicación 20: Un método de cultivo celular que utiliza un medio inicial caracterizado porque un aditivo de medio de cultivo obtenido de organismos con un contenido de cobre medido ha sido añadido al medio inicial. Reivindicación 26: Un proceso para producir una composición farmacéutica que contiene una proteína deseada, caracterizado porque comprende las etapas de: 1) producir la proteína deseada mediante el proceso de producción de acuerdo a la reivindicación 25; y 2) producir la composición farmacéutica mediante la mezcla de la proteína deseada producida en la etapa 1) con un vehículo y un aditivo que son aceptables para uso farmacéutico y formular la misma.
ARP160100777A 2015-03-26 2016-03-23 Proceso de producción con iones de cobre controlados AR104050A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015063662 2015-03-26

Publications (1)

Publication Number Publication Date
AR104050A1 true AR104050A1 (es) 2017-06-21

Family

ID=56977504

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160100777A AR104050A1 (es) 2015-03-26 2016-03-23 Proceso de producción con iones de cobre controlados

Country Status (13)

Country Link
US (2) US11046772B2 (es)
EP (2) EP4219694A1 (es)
JP (1) JP6752776B2 (es)
CN (1) CN107406832A (es)
AR (1) AR104050A1 (es)
AU (2) AU2016237086B2 (es)
BR (1) BR112017020401B1 (es)
CA (1) CA2980695A1 (es)
IL (1) IL254668B (es)
MX (2) MX2017012223A (es)
SG (1) SG11201707873TA (es)
TW (1) TWI716392B (es)
WO (1) WO2016153041A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
HUE067718T2 (hu) 2009-10-26 2024-11-28 Hoffmann La Roche Eljárás glikozilált immunglobulin elõállítására
EP2787007A3 (en) 2010-11-08 2015-03-11 F. Hoffmann-La Roche AG Subcutaneously administered ANTI-IL-6 receptor antibody
AR104050A1 (es) * 2015-03-26 2017-06-21 Chugai Pharmaceutical Co Ltd Proceso de producción con iones de cobre controlados
EP3971200A4 (en) * 2019-05-15 2023-08-02 Sekisui Chemical Co., Ltd. CELL CULTURE SCAFFOLD MATERIAL AND CELL CULTURE VESSEL

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100249937B1 (ko) 1991-04-25 2000-04-01 나가야마 오사무 인간 인터루킨-6 수용체에 대한 재구성 인간 항체
JP3630453B2 (ja) 1994-09-30 2005-03-16 中外製薬株式会社 Ｉｌ−６レセプター抗体を有効成分とする未熟型骨髄腫細胞治療剤
JP3822137B2 (ja) * 2002-05-20 2006-09-13 中外製薬株式会社 動物細胞培養用培地の添加剤およびそれを用いたタンパク質の製造方法
US8398980B2 (en) 2004-03-24 2013-03-19 Chugai Seiyaku Kabushiki Kaisha Subtypes of humanized antibody against interleuken-6 receptor
DK1835022T3 (en) * 2005-01-05 2015-02-23 Chugai Pharmaceutical Co Ltd CELL CULTIVATION PROCEDURE AND UTILIZATION OF THIS
RU2009132986A (ru) * 2007-03-02 2011-04-10 Уайт (Us) Применение меди и глутамата в культуре клеток для производства полипептидов
TW200902708A (en) * 2007-04-23 2009-01-16 Wyeth Corp Methods of protein production using anti-senescence compounds
HUE067718T2 (hu) * 2009-10-26 2024-11-28 Hoffmann La Roche Eljárás glikozilált immunglobulin elõállítására
US9458222B2 (en) * 2010-07-08 2016-10-04 Baxalta Incorporated Method of producing recombinant ADAMTS13 in cell culture
JP6176849B2 (ja) * 2011-07-19 2017-08-09 中外製薬株式会社 アルギニンアミドまたはその類似化合物を含む安定なタンパク質含有製剤
EP2968544A4 (en) * 2013-03-15 2016-10-12 Hoffmann La Roche CELL CULTURE MEDIA AND METHOD FOR PRODUCING ANTIBODY
EP3036254A1 (en) * 2013-08-20 2016-06-29 LEK Pharmaceuticals d.d. Cell culture medium and process for controlling -amidation and/or c-terminal amino acid cleavage of polypeptides
WO2015143512A2 (en) * 2014-03-23 2015-10-01 Advantech Bioscience Farmacêutica Ltda. Enhancement of recombinant protein expression with copper
AR104050A1 (es) * 2015-03-26 2017-06-21 Chugai Pharmaceutical Co Ltd Proceso de producción con iones de cobre controlados

Also Published As

Publication number Publication date
AU2022204600B2 (en) 2024-10-17
BR112017020401B1 (pt) 2021-04-06
US11046772B2 (en) 2021-06-29
EP3276001A4 (en) 2018-09-12
AU2016237086A1 (en) 2017-10-19
EP3276001A1 (en) 2018-01-31
AU2022204600A1 (en) 2022-07-21
WO2016153041A1 (ja) 2016-09-29
IL254668B (en) 2021-01-31
CA2980695A1 (en) 2016-09-29
MX2017012223A (es) 2018-01-30
AU2016237086B2 (en) 2022-04-14
JPWO2016153041A1 (ja) 2018-01-18
US20180051090A1 (en) 2018-02-22
US20210269536A1 (en) 2021-09-02
MX2022003016A (es) 2022-04-07
SG11201707873TA (en) 2017-10-30
TWI716392B (zh) 2021-01-21
CN107406832A (zh) 2017-11-28
BR112017020401A2 (pt) 2018-06-05
JP6752776B2 (ja) 2020-09-09
EP4219694A1 (en) 2023-08-02
TW201708532A (zh) 2017-03-01
IL254668A0 (en) 2017-11-30

Similar Documents

Publication Publication Date Title
MX2023004157A (es) Composiciones de oligosacaridos para el uso como alimento para animales y sus metodos para producirlas.
AR104050A1 (es) Proceso de producción con iones de cobre controlados
BR112018002214A2 (pt) ?métodos para cultivar células e para produzir uma proteína, meios de cultura de células cho e de batelada alimentada e/ou alimentação, e, alimentação de cultura de células cho?
CR20180525A (es) Producción de ácido ribonucleico libre de células
MX2018010529A (es) Composiciones y metodos para la produccion y administracion de acido ribonucleico.
BR112017027527A2 (pt) ?método para a produção de feromônios de mariposas em levedura
MX2020000369A (es) Metodos biologicos para preparar terpenos.
CL2017000754A1 (es) Proceso para producir una biomasa que contiene pufa que tiene alta estabilidad celular
EA201690849A1 (ru) Составы со стриголактоном и их применения
BR112015023036A2 (pt) método para preparar um produto alcaloide benzilisoquinolina e célula microbiana engenheirada que produz um produto alcaloide benzilisoquinolina
MX2021011676A (es) Polimorfos de sepiapterina y sales de los mismos.
CO2019008826A2 (es) Celulas microbianas, metodos para producir las mismas, y usos de las mismas
GB2548740A (en) Methods for generation of podocytes from pluripotent stem cells and cells produced by the same
MX2021002220A (es) Forma cristalina de base libre de lorlatinib.
PE20141133A1 (es) Aparato y proceso para la produccion de un producto de celulas encapsuladas
WO2017051347A3 (en) Cells and method of cell culture
MX2017006942A (es) Nuevos derivados de ester fosforamidato 3'-desoxiadenosina de 2' y/o 5' aminoacido como compuestos anti-cancer.
MX2015012168A (es) Expansión de celulas madre adultas in vitro.
AR093398A1 (es) PROPAGACION DE LEVADURA A UN pH CONTROLADO
MX2015011781A (es) Medio de cultivo celular y metodos de produccion de anticuerpos.
BR112018007590A2 (pt) método para produzir proteína de fusão que tem domínio fc de igg
MX2018003354A (es) Seleccion de celulas pluripotentes para producir ratones hembra xy fertiles.
AR103041A1 (es) Supresión de arni parental de gen hunchback para el control de las plagas de hemípteros
BR112018000168A2 (pt) método para produção de células ips de alta qualidade
BR112016009619A2 (pt) métodos para sacarificar um material celulósico e para produzir um produto de fermentação a partir de material celulósico