AR089441A1 - Capsulas de gelatina/alginato de liberacion retardada que comprenden acidos grasos omega-3 y metodos y usos de las mismas, metodo de manufactura, composicion farmaceutica - Google Patents
Capsulas de gelatina/alginato de liberacion retardada que comprenden acidos grasos omega-3 y metodos y usos de las mismas, metodo de manufactura, composicion farmaceuticaInfo
- Publication number
- AR089441A1 AR089441A1 ARP120104950A ARP120104950A AR089441A1 AR 089441 A1 AR089441 A1 AR 089441A1 AR P120104950 A ARP120104950 A AR P120104950A AR P120104950 A ARP120104950 A AR P120104950A AR 089441 A1 AR089441 A1 AR 089441A1
- Authority
- AR
- Argentina
- Prior art keywords
- alginate
- gelatin
- delayed
- capsule
- mpa
- Prior art date
Links
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 title abstract 19
- 229940072056 alginate Drugs 0.000 title abstract 19
- 235000010443 alginic acid Nutrition 0.000 title abstract 19
- 229920000615 alginic acid Polymers 0.000 title abstract 19
- 239000002775 capsule Substances 0.000 title abstract 17
- 229920000159 gelatin Polymers 0.000 title abstract 15
- 239000008273 gelatin Substances 0.000 title abstract 15
- 108010010803 Gelatin Proteins 0.000 title abstract 14
- 235000019322 gelatine Nutrition 0.000 title abstract 14
- 235000011852 gelatine desserts Nutrition 0.000 title abstract 14
- 230000003111 delayed effect Effects 0.000 title abstract 11
- 238000000034 method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940012843 omega-3 fatty acid Drugs 0.000 title 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 title 1
- 239000006014 omega-3 oil Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 6
- 239000011248 coating agent Substances 0.000 abstract 6
- 238000000576 coating method Methods 0.000 abstract 6
- 239000000203 mixture Substances 0.000 abstract 5
- 239000007902 hard capsule Substances 0.000 abstract 3
- 239000007901 soft capsule Substances 0.000 abstract 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 abstract 1
- AEMOLEFTQBMNLQ-BZINKQHNSA-N D-Guluronic Acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@@H](O)[C@H]1O AEMOLEFTQBMNLQ-BZINKQHNSA-N 0.000 abstract 1
- AEMOLEFTQBMNLQ-VANFPWTGSA-N D-mannopyranuronic acid Chemical group OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H]1O AEMOLEFTQBMNLQ-VANFPWTGSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- AEMOLEFTQBMNLQ-UHFFFAOYSA-N beta-D-galactopyranuronic acid Natural products OC1OC(C(O)=O)C(O)C(O)C1O AEMOLEFTQBMNLQ-UHFFFAOYSA-N 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 235000015872 dietary supplement Nutrition 0.000 abstract 1
- 235000012041 food component Nutrition 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 235000010408 potassium alginate Nutrition 0.000 abstract 1
- 239000000737 potassium alginate Substances 0.000 abstract 1
- MZYRDLHIWXQJCQ-YZOKENDUSA-L potassium alginate Chemical group [K+].[K+].O1[C@@H](C([O-])=O)[C@@H](OC)[C@H](O)[C@H](O)[C@@H]1O[C@@H]1[C@@H](C([O-])=O)O[C@@H](O)[C@@H](O)[C@H]1O MZYRDLHIWXQJCQ-YZOKENDUSA-L 0.000 abstract 1
- 235000010413 sodium alginate Nutrition 0.000 abstract 1
- 239000000661 sodium alginate Substances 0.000 abstract 1
- 229940005550 sodium alginate Drugs 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A61K9/5057—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
Cápsulas de liberación retardada y métodos para manufacturarlas. Las cápsulas comprenden un recubrimiento capsular comprende una combinación de gelatina y alginato. donde el recubrimiento capsular comprende al menos un agente encapsulado o está relleno con al menos un agente, y donde las cápsulas de liberación retardada se seleccionan entre las cápsulas blandas y las cápsulas duras. Reivindicación 1: Una cápsula de liberación retardada caracterizada porque comprende un recubrimiento capsular que comprende una combinación de una gelatina que se selecciona entre una gelatina del tipo A y una combinación de una gelatina del tipo A y una gelatina del tipo B, donde la gelatina tiene una viscosidad inferior a aproximadamente 4,2 mPa×segundo y/o un valor de Bloom inferior a aproximadamente 290 g; y un alginato, en una cantidad que varía entre aproximadamente 0,2% y aproximadamente 20%, con relación al peso de la gelatina, donde el alginato tiene una viscosidad que varía entre aproximadamente 2 y aproximadamente 600 mPa×segundo; donde el recubrimiento capsular comprende al menos un agente encapsulado o está relleno con al menos un agente, y donde la cápsula de liberación retardada se selecciona entre una cápsula blanda y una cápsula dura, con la condición de que, cuando el alginato sea un alginato rico en G, la viscosidad del alginato no se encuentre en el rango de entre aproximadamente 45 mPa×segundo y aproximadamente 420 mPa×segundo. Reivindicación 2: La cápsula de liberación retardada de acuerdo con la reivindicación 1, caracterizada porque la cápsula se selecciona entre una cápsula de liberación sostenida, una cápsula de liberación controlada y una cápsula gastrorresistente. Reivindicación 19: La cápsula de liberación retardada de acuerdo con la reivindicación 1, caracterizada porque el alginato se selecciona entre el alginato de potasio, el alginato de sodio, el alginato de polietilenglicol y las mezclas de éstos. Reivindicación 20: La cápsula de liberación retardada de acuerdo con la reivindicación 1, caracterizada porque el alginato se selecciona entre un alginato que comprende una fracción elevada de residuos de ácido manurónico (un alginato rico en M) y un alginato que comprende una fracción elevada de residuos de ácido gulurónico (un alginato rico en G). Reivindicación 112: La cápsula de liberación retardada de acuerdo con la reivindicación 1 o la reivindicación 59, caracterizada porque la cápsula se selecciona entre una composición farmacéutica, una composición nutricional, una composición que es útil como suplemento alimenticio y un ingrediente para la dieta. Reivindicación 207: Una composición/mezcla de alginato-gelatina para elaborar una cápsula de liberación retardada, caracterizada porque comprende un recubrimiento capsular que comprende una combinación de una gelatina que se selecciona entre una gelatina del tipo A y una combinación de una gelatina del tipo A y una gelatina del tipo B, donde la gelatina tiene una viscosidad inferior a aproximadamente 4,2 mPa×segundo y/o un valor de Bloom inferior a aproximadamente 290 g; y un alginato, en una cantidad que varía entre aproximadamente 0,2% y aproximadamente 20%, con relación al peso de la gelatina, donde el alginato tiene una viscosidad que varía entre aproximadamente 2 mPa×segundo y aproximadamente 600 mPa×segundo; donde el recubrimiento capsular comprende al menos un agente encapsulado o está relleno con al menos un agente, y donde la cápsula de liberación retardada se selecciona entre una cápsula blanda y una cápsula dura, con la condición de que, cuando el alginato sea un alginato rico en G, la viscosidad del alginato no se encuentre en el rango de entre aproximadamente 45 mPa×segundo y aproximadamente 420 mPa×segundo.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579374P | 2011-12-22 | 2011-12-22 | |
| US201261710483P | 2012-10-05 | 2012-10-05 | |
| US201261718950P | 2012-10-26 | 2012-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR089441A1 true AR089441A1 (es) | 2014-08-20 |
Family
ID=47747685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120104950A AR089441A1 (es) | 2011-12-22 | 2012-12-21 | Capsulas de gelatina/alginato de liberacion retardada que comprenden acidos grasos omega-3 y metodos y usos de las mismas, metodo de manufactura, composicion farmaceutica |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9456991B2 (es) |
| EP (1) | EP2793867B1 (es) |
| AR (1) | AR089441A1 (es) |
| TW (1) | TW201343203A (es) |
| WO (1) | WO2013093630A2 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR089441A1 (es) | 2011-12-22 | 2014-08-20 | Baes Erik | Capsulas de gelatina/alginato de liberacion retardada que comprenden acidos grasos omega-3 y metodos y usos de las mismas, metodo de manufactura, composicion farmaceutica |
| GB201216385D0 (en) * | 2012-09-13 | 2012-10-31 | Chrysalis Pharma Ag | A pharmaceutical composition |
| GB201402457D0 (en) * | 2014-02-12 | 2014-03-26 | Aker Biomarine As | Capsules containing high doses of phospholipids |
| GB201402450D0 (en) | 2014-02-12 | 2014-03-26 | Aker Biomarine As | Liquid phospholipid-containing compositions for preperation of pharmaceuticals |
| CN103976981B (zh) * | 2014-05-16 | 2016-08-24 | 吉林农业大学 | 一种虫草素纳米缓释囊及其制备方法 |
| BR112016028561A8 (pt) | 2014-06-06 | 2021-06-29 | Marine Ingredients Llc | composição e forma de dosagem compreendendo um óleo marinho que compreende ácidos graxos, e, uso das mesmas |
| WO2015200149A1 (en) * | 2014-06-23 | 2015-12-30 | Banner Life Sciences Llc | All natural enteric soft capsules comprising active ingredients |
| MA40846A (fr) * | 2014-10-10 | 2017-09-05 | Sancilio & Company Inc | Compositions d'acides gras et d'esters d'acides gras auto-micellisantes, ainsi que leur utilisation dans le traitement d'états pathologiques |
| US20160278372A1 (en) * | 2015-03-27 | 2016-09-29 | Andrew TENG | Tiny particles for control-release and method of manufacturing the same |
| US10966937B2 (en) * | 2015-05-04 | 2021-04-06 | Cytometix, Inc. | Compositions and methods for delivery of polyunsaturated fatty acid derivatives and analogs |
| CN105231167B (zh) * | 2015-10-23 | 2018-01-12 | 福州大学 | 一种以魔芋胶为壁材包埋微藻油制成微胶囊的方法 |
| EP3456322A4 (en) * | 2016-05-11 | 2020-01-01 | Blanco Fernández, María Del Carmen | SINGLE DOSE CONTAINER AND METHOD FOR THE PRODUCTION THEREOF |
| BR112019012741A2 (pt) * | 2016-12-23 | 2019-11-26 | Basf As | composição, formulação, método para prevenir e/ou tratar caquexia em um indivíduo, uso da composição, e, produto de uso médico especial, produto de alimentos para uso específico de saúde, produto para alimentos para fins médicos especiais, produto de alimento para uso dietético especial, produto de nutrição médica e produto de alimento médico. |
| US11596607B2 (en) * | 2017-04-18 | 2023-03-07 | Actorious Innovations And Research Pvt. Ltd. | Polymer based formulation for release of drugs and bioactives at specific GIT sites |
| US11896720B2 (en) * | 2017-09-26 | 2024-02-13 | Captek Softgel International | Orally available articles containing at least one stabilized supplement therein |
| CN108073906B (zh) * | 2017-12-27 | 2021-04-30 | 广东美的厨房电器制造有限公司 | 菜品营养成分检测方法、装置、烹饪器具和可读存储介质 |
| WO2020247352A1 (en) * | 2019-06-03 | 2020-12-10 | R.P. Scherer Technologies, Llc | Delayed release softgel capsules |
| CN113924083A (zh) * | 2019-06-14 | 2022-01-11 | 森下仁丹株式会社 | 延迟崩解型胶囊及其制造方法 |
| CA3159407A1 (en) * | 2019-10-28 | 2021-05-06 | R.P. Scherer Technologies, Llc | Delayed release softgel capsules in higher ph environment |
| CN113559079B (zh) * | 2020-04-28 | 2023-10-20 | 江苏恒瑞医药股份有限公司 | 一种软胶囊及其制备方法和用途 |
| CN112518804B (zh) * | 2021-01-14 | 2022-10-11 | 重庆云海机械制造有限公司 | 一种机械手臂高效自动清洁装置 |
| CN117750941A (zh) * | 2021-07-29 | 2024-03-22 | 营养与生物科学美国1有限责任公司 | 可生物降解的海藻酸盐膜 |
| ES2939432B2 (es) * | 2021-10-21 | 2024-11-05 | Creaciones Aromaticas Ind S A | Salsa para su uso en envases biodegradables |
| WO2023167803A1 (en) * | 2022-03-01 | 2023-09-07 | Sittner Edward Oscar | Method of manufacture of active ingredient infused gelatin capsule |
| DE102023121056A1 (de) * | 2023-08-08 | 2025-02-13 | Gelita Ag | Gelatineweichkapsel und Verfahren zur Herstellung |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US470883A (en) | 1892-03-15 | Island | ||
| JPS58194810A (ja) | 1982-05-07 | 1983-11-12 | Morishita Jintan Kk | コ−テイング軟ミニカプセル |
| JPS59140860A (ja) | 1983-01-28 | 1984-08-13 | Nippon Suisan Kaisha Ltd | 魚翅類似食品を製造する方法及び装置 |
| BG46154A3 (bg) | 1983-02-18 | 1989-10-16 | Warner-Lambert Company Llc | Метод за получаване на капсули |
| JPS61126016A (ja) | 1984-11-22 | 1986-06-13 | Toagosei Chem Ind Co Ltd | 不飽和脂肪酸を内相物としたマイクロカプセル |
| JPH01176369A (ja) | 1987-12-29 | 1989-07-12 | Fuji Electric Co Ltd | ディスク記憶装置のトラック照合用標識 |
| JPH01313421A (ja) | 1988-06-13 | 1989-12-18 | Arimento Kogyo Kk | アルギン酸配合剤皮軟カプセルとその製造方法 |
| US6482516B1 (en) | 1993-07-20 | 2002-11-19 | Banner Pharmacaps, Inc. | Enrobed tablet |
| JPH0427352A (ja) * | 1990-05-22 | 1992-01-30 | Fuji Capsule Kk | 健康食品用腸溶性軟カプセル |
| JPH0436159A (ja) | 1990-05-31 | 1992-02-06 | Fuji Capsule Kk | ローヤルゼリー軟カプセル |
| JPH04207352A (ja) | 1990-11-29 | 1992-07-29 | Olympus Optical Co Ltd | 画像データの符号化装置および符号化方法 |
| JPH0532543A (ja) | 1991-07-31 | 1993-02-09 | Ina Shokuhin Kogyo Kk | 腸溶性カプセル |
| JP3312038B2 (ja) | 1991-11-01 | 2002-08-05 | ポーラ化成工業株式会社 | グ ミ |
| JPH05245366A (ja) | 1992-03-04 | 1993-09-24 | Morishita Jintan Kk | 内側面が非水溶化された皮膜を有するシームレスカプセルとその製造方法 |
| MY118354A (en) | 1995-05-01 | 2004-10-30 | Scarista Ltd | 1,3-propane diol derivatives as bioactive compounds |
| US5882715A (en) | 1995-06-20 | 1999-03-16 | Pharma-Vinci A/S | Method of preparing an oral preparation provided on the outer side with an enteric coating, as well as an oral preparation obtained by the method |
| US6030641A (en) | 1997-06-03 | 2000-02-29 | Uni Colloid Kabushiki Kaisha | Sustained release capsule and method for preparing the same |
| KR100219918B1 (ko) | 1997-07-03 | 1999-09-01 | 김윤 | 대장선택적 약물전달용 조성물 |
| JPH1176369A (ja) * | 1997-09-12 | 1999-03-23 | Sansho Iyaku Kk | 腸溶性軟カプセル |
| JPH11302158A (ja) | 1998-04-16 | 1999-11-02 | Oruto Corporation:Kk | 腸溶性シームカプセルを用いた整腸作用を有する健康食品 |
| WO2000018254A2 (en) | 1998-09-25 | 2000-04-06 | Kemin Industries, Inc. | Method of protecting heat- or oxygen-labile compounds to preserve activity and bioavailability |
| EP1112740A1 (de) | 1999-12-30 | 2001-07-04 | Greither, Peter | Verwendung eines Polyglycerine enthaltenden wasserlöslichen Mittels |
| US6620571B2 (en) | 2000-03-17 | 2003-09-16 | Eastman Kodak Company | Method for producing microcapsules having improved wall characteristics |
| DE10015468A1 (de) | 2000-03-29 | 2001-10-11 | Basf Ag | Hartkapseln, enthaltend Polymerisate und Vinylestern und Polyethern, deren Verwendung und Herstellung |
| CN1141974C (zh) | 2000-06-07 | 2004-03-17 | 张昊 | 结肠定位释放的口服生物制剂 |
| EP1184033A1 (en) | 2000-09-01 | 2002-03-06 | Warner-Lambert Company | Pectin film compositions |
| NO20021592D0 (no) | 2002-04-04 | 2002-04-04 | Fmc Biopolymer As | Polysakkaridkapsler og fremgangsmåte ved fremstilling derav |
| US20040254357A1 (en) | 2002-12-19 | 2004-12-16 | Zaloga Gary P. | Fatty acid phenolic conjugates |
| CA2596023A1 (en) | 2005-01-27 | 2006-11-09 | Ocean Nutrition Canada Ltd. | Fatty acid-benzenediol derivatives and methods of making and using thereof |
| WO2006105173A2 (en) | 2005-03-28 | 2006-10-05 | Foodsource Lure Corporation | Oral delivery vehicle and material |
| US20070082046A1 (en) | 2005-10-11 | 2007-04-12 | Banner Pharmacaps, Inc. | Enteric valproic acid |
| US20070148248A1 (en) | 2005-12-22 | 2007-06-28 | Banner Pharmacaps, Inc. | Gastric reflux resistant dosage forms |
| WO2007098612A1 (en) | 2006-03-02 | 2007-09-07 | Laboratoires Mauves Inc. | Gastric acid resistant gelatin capsule composition and method for producing same |
| CN1846716A (zh) | 2006-05-12 | 2006-10-18 | 河北农业大学 | 一种功能性双歧杆菌微胶囊 |
| JP2009019696A (ja) | 2007-07-12 | 2009-01-29 | Panasonic Corp | 真空断熱材および真空断熱材を用いた建物 |
| DE102007039772A1 (de) | 2007-08-22 | 2009-02-26 | Cavis Microcaps Gmbh | Mikrokapsel und Verfahren zu deren Herstellung |
| US9186640B2 (en) | 2007-08-28 | 2015-11-17 | Pepsico, Inc. | Delivery and controlled release of encapsulated lipophilic nutrients |
| US20090074944A1 (en) | 2007-09-18 | 2009-03-19 | Viva Pharmaceuticals Inc. | Enteric coatings for orally ingestible compositions |
| JP4971298B2 (ja) | 2008-01-11 | 2012-07-11 | ユニメディカル株式会社 | 腸溶性・徐放性ソフトカプセル及びその製造方法 |
| JP5178236B2 (ja) * | 2008-02-25 | 2013-04-10 | クオリカプス株式会社 | 腸溶性カプセル |
| US20100062057A1 (en) | 2008-09-10 | 2010-03-11 | Pronova BioPharma Norge AS. | Formulation |
| CN101559045B (zh) | 2009-05-21 | 2011-05-25 | 阜宁怀仁生物有限公司 | 耐热型花生四烯酸营养微胶囊及其制备方法 |
| CN101628117B (zh) | 2009-08-18 | 2011-02-16 | 北京航洋胶囊技术有限公司 | 一种咀嚼软胶囊皮、咀嚼软胶囊药物及其制备方法 |
| CZ2010126A3 (cs) | 2010-02-18 | 2011-04-20 | Univerzita Tomáše Bati ve Zlíne | Suchá substance hydrogelu pro krytí ran a zpusob její prípravy |
| JP5829607B2 (ja) | 2010-06-30 | 2015-12-09 | 持田製薬株式会社 | ω３脂肪酸の配合製剤 |
| MX2013000703A (es) | 2010-07-19 | 2014-07-24 | Procaps Sa | Aparato y proceso para encapsular capsulas u otras formas de dosificacion solidas dentro de capsulas. |
| CN102198115B (zh) | 2011-05-19 | 2012-11-14 | 甘肃易源生物制药有限公司 | 一种中药提取液与益生菌混合的肠溶型微胶囊 |
| US20120301546A1 (en) * | 2011-05-26 | 2012-11-29 | Hassan Emadeldin M | Acid-resistant soft gel compositions |
| AR089441A1 (es) | 2011-12-22 | 2014-08-20 | Baes Erik | Capsulas de gelatina/alginato de liberacion retardada que comprenden acidos grasos omega-3 y metodos y usos de las mismas, metodo de manufactura, composicion farmaceutica |
-
2012
- 2012-12-21 AR ARP120104950A patent/AR089441A1/es not_active Application Discontinuation
- 2012-12-21 TW TW101148998A patent/TW201343203A/zh unknown
- 2012-12-21 EP EP12826539.4A patent/EP2793867B1/en active Active
- 2012-12-21 WO PCT/IB2012/003014 patent/WO2013093630A2/en active Application Filing
-
2014
- 2014-06-20 US US14/310,041 patent/US9456991B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2793867A2 (en) | 2014-10-29 |
| WO2013093630A3 (en) | 2013-12-27 |
| US20150004226A1 (en) | 2015-01-01 |
| WO2013093630A2 (en) | 2013-06-27 |
| US9456991B2 (en) | 2016-10-04 |
| EP2793867B1 (en) | 2021-01-20 |
| TW201343203A (zh) | 2013-11-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR089441A1 (es) | Capsulas de gelatina/alginato de liberacion retardada que comprenden acidos grasos omega-3 y metodos y usos de las mismas, metodo de manufactura, composicion farmaceutica | |
| CL2008001180A1 (es) | Un polvo bebestible instantaneo que comprende un agente de relleno y/o azucar recubiertas al menos parcialmente con un 0,1-5% de aceite de cadenas cortas de acidos grasos saturados de trigleceridos saturados c4-c14; capsula que comprende el polvo bebestible; metodo de produccion del polvo; kit que comprende un polvo bebestible. | |
| HRP20171766T1 (hr) | Stabilni farmaceutski pripravak i postupci njegove uporabe | |
| HRP20200859T1 (hr) | Meke kapsule kalcifediola | |
| MX2017012878A (es) | Composiciones gomosas de multicomponentes con nucleo duro. | |
| JP2018184458A5 (es) | ||
| PE20081684A1 (es) | Microcapsulas vegetarianas | |
| RU2017129161A (ru) | Композиции липидов | |
| BR112012026758A2 (pt) | cápsula, método para produzir cápsulas com uma estrutura de núcleo/envoltório, usos de cápsulas com uma estrutura de núcleo/envoltório, e de preparações pulverulentas ou líquidas, e, composição farmacêutica, de cosméticos, preparação de proteção de cultura, alimentação de animal, suplemento alimetar ou nutricional | |
| JP2014508156A5 (es) | ||
| JP2018511560A5 (es) | ||
| AR052297A1 (es) | Composiciones de confiteria con material de relleno central | |
| BR112017028300A2 (pt) | composição nutricional, creme de café, métodos para fabricação de caseína micelar e para preparação uma composição nutricional | |
| AR110060A1 (es) | Composiciones nutricionales que proporcionan el manejo dietético de cólicos | |
| GB2544204A (en) | Preparation and composition of medium chain triglycerides containing substantial amount of lauric acid | |
| ES2319684T3 (es) | Complemento alimenticio que incluye una asociacion de agentes antioxidantes y carnitina o un precursor de la carnitina, como ayuda a la fertilidad en el hombre y la mujer. | |
| BR112015010371A8 (pt) | métodos para produzir composições antiperspirantes em bastão sólido | |
| AR124043A1 (es) | Cápsulas blandas de liberación retardada | |
| AR086366A1 (es) | Producto lacteo congelable | |
| WO2016137825A8 (en) | Millicapsule formulations comprising polyunsaturated free fatty acids | |
| AR083460A1 (es) | Hidrolizados de proteinas animales de origen marino con propiedades neuroprotectoras | |
| CO6341531A2 (es) | Producto alimenticio de acidos grasos con base de chia, rico en omega-3, con buena estabilidad | |
| BR112015028696A2 (pt) | composições de óleo estruturadas | |
| MX337313B (es) | Proceso para producir productos de confiteria congelados conformados. | |
| CA2858234C (en) | Stable formulations of antiplatelet agents, omega-3 fatty acids and amylose in soft gelatin capsules |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal | ||
| FB | Suspension of granting procedure |