AR084915A1 - Proceso para la preparacion de amidas del acido pirazol carboxilico - Google Patents
Proceso para la preparacion de amidas del acido pirazol carboxilicoInfo
- Publication number
- AR084915A1 AR084915A1 ARP120100211A ARP120100211A AR084915A1 AR 084915 A1 AR084915 A1 AR 084915A1 AR P120100211 A ARP120100211 A AR P120100211A AR P120100211 A ARP120100211 A AR P120100211A AR 084915 A1 AR084915 A1 AR 084915A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- oxygen
- compound
- sulfide
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
- C07C251/56—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/62—Oximes having oxygen atoms of oxyimino groups esterified
- C07C251/64—Oximes having oxygen atoms of oxyimino groups esterified by carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
- C07C329/02—Monothiocarbonic acids; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
- C07C329/02—Monothiocarbonic acids; Derivatives thereof
- C07C329/04—Esters of monothiocarbonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/60—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members
- C07C2603/66—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
La presente se relaciona con un proceso de preparación de ácido 3-difluorometil-1-metil-1H-pirazol-4-carboxílico (9-diclorometileno-1,2,3,4-tetrahidro-1,4-metano-naftaleno-5-il)-amida mediante la acilación del oxígeno de la oxima del compuesto de fórmula (1), en presencia de un solvente y de un agente de acilación de la fórmula: R1-C(X)-Cl; donde X es oxígeno o sulfuro; R1 es cloro si X es oxígeno o sulfuro; o R1 es alcoxi C1-6, CH3-C(=CH2)-O-, fenoxi o triclorometoxi si X es oxígeno; y a) si R1 es cloro y el compuesto de fórmula: R1-C(X)-Cl se agregó al compuesto de fórmula (1); en el que se hace reaccionar el producto obtenido de la fórmula (2) donde X es oxígeno o sulfuro, con el compuesto de fórmula (3); o b) si R1 es cloro y el compuesto de fórmula (1) se agregó al compuesto de fórmula: R1-C(X)-Cl; o R1 es alcoxi C1-6, CH3-C(=CH2)-O-, fenoxi o triclorometoxi si X es oxígeno; en el que se hace reaccionar el producto obtenido de la fórmula (4), donde X es oxígeno o sulfuro; R1 es cloro si X es oxígeno o sulfuro; o R1 es alcoxi C1-6, CH3-C(=CH2)-O-, fenoxi o triclorometoxi si X es oxígeno, con el compuesto de fórmula (3).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11151965 | 2011-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR084915A1 true AR084915A1 (es) | 2013-07-10 |
Family
ID=45524566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120100211A AR084915A1 (es) | 2011-01-25 | 2012-01-23 | Proceso para la preparacion de amidas del acido pirazol carboxilico |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8895757B2 (es) |
| EP (1) | EP2668166B1 (es) |
| JP (2) | JP6133788B2 (es) |
| KR (1) | KR101851781B1 (es) |
| CN (1) | CN103339113B (es) |
| AR (1) | AR084915A1 (es) |
| AU (1) | AU2012210547B2 (es) |
| BR (1) | BR112013018533A2 (es) |
| CA (1) | CA2824730C (es) |
| CO (1) | CO6751253A2 (es) |
| ES (1) | ES2540211T3 (es) |
| HR (1) | HRP20150658T1 (es) |
| IL (1) | IL227317A (es) |
| MX (1) | MX352697B (es) |
| PL (1) | PL2668166T3 (es) |
| PT (1) | PT2668166E (es) |
| TW (1) | TWI534126B (es) |
| UY (1) | UY33879A (es) |
| WO (1) | WO2012101139A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI534126B (zh) * | 2011-01-25 | 2016-05-21 | 先正達合夥公司 | 用於製備吡唑羧酸醯胺之方法 |
| TWI510472B (zh) | 2012-02-15 | 2015-12-01 | Syngenta Participations Ag | 立體選擇性製備吡唑羧醯胺之方法 |
| EP3575030B1 (en) | 2017-03-31 | 2024-01-03 | NSK Ltd. | Laser welding device, laser processing device, laser welding method, bearing manufacturing method, machine manufacturing method, vehicle manufacturing method, bearing, machine, and vehicle |
| IL318101A (en) | 2022-07-22 | 2025-02-01 | Syngenta Crop Protection Ag | Solid form of a heterocyclic amide derivative |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58194853A (ja) * | 1982-05-11 | 1983-11-12 | Showa Denko Kk | シクロヘキセン−アセチルオキシム誘導体 |
| US5093347A (en) | 1991-01-28 | 1992-03-03 | Monsanto Company | 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use |
| SI1940813T1 (sl) * | 2005-10-25 | 2011-02-28 | Syngenta Participations Ag | Heterociklični amidni derivati, uporabni kot mikrobiocidi |
| EP2280944A1 (en) | 2008-05-14 | 2011-02-09 | Syngenta Limited | Process for the preparation of amides |
| EP2370412A1 (en) | 2008-12-24 | 2011-10-05 | Syngenta Limited | Methods for the preparation of fungicides |
| BR112012002641B1 (pt) | 2009-08-06 | 2018-05-22 | Syngenta Participations Ag | Processo de preparação de amidas de ácido carboxílico pirazol, bem como compostos intermediários |
| WO2011131546A1 (en) | 2010-04-20 | 2011-10-27 | Syngenta Participations Ag | Process for the preparation of pyrazole carboxylic acid amides |
| EP2560960B1 (en) | 2010-04-20 | 2014-02-26 | Syngenta Participations AG | Process for the preparation of pyrazole carboxylic acid amides |
| EP2560959B1 (en) | 2010-04-20 | 2014-08-20 | Syngenta Participations AG | Process for the preparation of pyrazole carboxylic acid amides |
| TWI534126B (zh) * | 2011-01-25 | 2016-05-21 | 先正達合夥公司 | 用於製備吡唑羧酸醯胺之方法 |
-
2012
- 2012-01-20 TW TW101102374A patent/TWI534126B/zh active
- 2012-01-23 AR ARP120100211A patent/AR084915A1/es active IP Right Grant
- 2012-01-25 CN CN201280006384.7A patent/CN103339113B/zh active Active
- 2012-01-25 MX MX2013007914A patent/MX352697B/es active IP Right Grant
- 2012-01-25 JP JP2013549849A patent/JP6133788B2/ja active Active
- 2012-01-25 CA CA2824730A patent/CA2824730C/en active Active
- 2012-01-25 PT PT127008597T patent/PT2668166E/pt unknown
- 2012-01-25 BR BR112013018533A patent/BR112013018533A2/pt active IP Right Grant
- 2012-01-25 US US13/981,913 patent/US8895757B2/en active Active
- 2012-01-25 AU AU2012210547A patent/AU2012210547B2/en active Active
- 2012-01-25 EP EP12700859.7A patent/EP2668166B1/en active Active
- 2012-01-25 PL PL12700859T patent/PL2668166T3/pl unknown
- 2012-01-25 WO PCT/EP2012/051075 patent/WO2012101139A1/en active Application Filing
- 2012-01-25 ES ES12700859.7T patent/ES2540211T3/es active Active
- 2012-01-25 UY UY0001033879A patent/UY33879A/es active IP Right Grant
- 2012-01-25 KR KR1020137022399A patent/KR101851781B1/ko active IP Right Grant
-
2013
- 2013-07-04 IL IL227317A patent/IL227317A/en active IP Right Grant
- 2013-07-23 CO CO13173578A patent/CO6751253A2/es unknown
-
2015
- 2015-06-17 HR HRP20150658TT patent/HRP20150658T1/hr unknown
-
2016
- 2016-11-07 JP JP2016217091A patent/JP6419131B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6419131B2 (ja) | 2018-11-07 |
| MX2013007914A (es) | 2013-08-29 |
| IL227317A (en) | 2014-11-30 |
| AU2012210547A1 (en) | 2013-08-01 |
| CA2824730A1 (en) | 2012-08-02 |
| CO6751253A2 (es) | 2013-09-16 |
| PL2668166T3 (pl) | 2015-09-30 |
| MX352697B (es) | 2017-12-05 |
| KR20140019333A (ko) | 2014-02-14 |
| TW201245114A (en) | 2012-11-16 |
| JP2017071614A (ja) | 2017-04-13 |
| PT2668166E (pt) | 2015-08-27 |
| HRP20150658T1 (hr) | 2015-07-31 |
| US8895757B2 (en) | 2014-11-25 |
| EP2668166A1 (en) | 2013-12-04 |
| BR112013018533A2 (pt) | 2016-07-12 |
| TWI534126B (zh) | 2016-05-21 |
| UY33879A (es) | 2012-08-31 |
| EP2668166B1 (en) | 2015-05-13 |
| US20130310592A1 (en) | 2013-11-21 |
| JP6133788B2 (ja) | 2017-05-24 |
| CN103339113B (zh) | 2015-07-22 |
| ES2540211T3 (es) | 2015-07-09 |
| JP2014504596A (ja) | 2014-02-24 |
| WO2012101139A1 (en) | 2012-08-02 |
| KR101851781B1 (ko) | 2018-04-24 |
| CA2824730C (en) | 2018-10-23 |
| CN103339113A (zh) | 2013-10-02 |
| AU2012210547B2 (en) | 2016-04-14 |
| IL227317A0 (en) | 2013-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |