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MX347564B - Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo. - Google Patents

Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo.

Info

Publication number
MX347564B
MX347564B MX2014009948A MX2014009948A MX347564B MX 347564 B MX347564 B MX 347564B MX 2014009948 A MX2014009948 A MX 2014009948A MX 2014009948 A MX2014009948 A MX 2014009948A MX 347564 B MX347564 B MX 347564B
Authority
MX
Mexico
Prior art keywords
formula
methyl
compound
preparation
difluoromethyl
Prior art date
Application number
MX2014009948A
Other languages
English (en)
Other versions
MX2014009948A (es
Inventor
Walter Harald
Stierli Daniel
Rommel Michael
Georg Hanreich Reinhard
Zeller Martin
Vettiger Thomas
Smejkal Thomas
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of MX2014009948A publication Critical patent/MX2014009948A/es
Publication of MX347564B publication Critical patent/MX347564B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La invención se refiere a un proceso para preparar un compuesto de fórmula I (ver Fórmula) donde R1, R2 y R3 son como se definen en la reivindicación 1, comprendiendo el proceso a) añadir un compuesto de fórmula II (ver Fórmula) en presencia de un disolvente orgánico inerte, a una mezcla que comprende un nitrito orgánico de fórmula III (R4-O-N=O (III)), donde R4 es alquilo C1-C8, un compuesto de fórmula IV (ver Fórmula) b) hacer reaccionar el compuesto resultante de fórmula V (ver Fórmula) con H2N-O-CH3 para obtener el compuesto de fórmula VII (ver Fórmula) c) reducir el compuesto de fórmula VII para obtener el compuesto de fórmula VIII (ver Fórmula) d) y hacer reaccionar el compuesto de fórmula VIII con un compuesto de fórmula IX (ver Fórmula) donde R* es halógeno, hidroxi o alcoxi C1-6, para obtener el compuesto de fórmula I.
MX2014009948A 2012-02-28 2013-02-26 Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo. MX347564B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12157354 2012-02-28
PCT/EP2013/053773 WO2013127764A1 (en) 2012-02-28 2013-02-26 Process for the preparation of phenyl substituted 3 - difluoromethyl - 1 -methyl - 1h - pyrazole - 4 - carboxylic n-methoxy- [1 -methyl- 2 - phenylethyl] amides

Publications (2)

Publication Number Publication Date
MX2014009948A MX2014009948A (es) 2014-11-12
MX347564B true MX347564B (es) 2017-05-03

Family

ID=47748653

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014009948A MX347564B (es) 2012-02-28 2013-02-26 Proceso para la preparacion de n-metoxi-[1-metil-2-feniletil]amida s del acido 3-difluorometil-1-metil-1h-pirazol-4-carboxilico sustituidas con fenilo.

Country Status (20)

Country Link
US (1) US9051272B2 (es)
EP (1) EP2819997B1 (es)
JP (1) JP6078563B2 (es)
KR (1) KR102031809B1 (es)
CN (1) CN104144914B (es)
AR (1) AR090172A1 (es)
AU (1) AU2013225123B2 (es)
BR (1) BR112014020556B1 (es)
CA (1) CA2863467C (es)
CO (1) CO7051031A2 (es)
DK (1) DK2819997T3 (es)
ES (1) ES2558586T3 (es)
HR (1) HRP20160001T1 (es)
HU (1) HUE026564T2 (es)
IL (1) IL233937A (es)
MX (1) MX347564B (es)
PL (1) PL2819997T3 (es)
TW (1) TWI491594B (es)
WO (1) WO2013127764A1 (es)
ZA (1) ZA201405823B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201811156T4 (tr) 2014-02-19 2018-08-27 Basf Agro Bv Pirazolkarboksilik asit alkoksiamidlerin fungisidal kompozisyonları.
WO2016174042A1 (en) 2015-04-27 2016-11-03 BASF Agro B.V. Pesticidal compositions
WO2017207368A1 (en) 2016-06-02 2017-12-07 BASF Agro B.V. Fungicidal compositions
CN108610290B (zh) * 2018-06-11 2020-04-24 武汉工程大学 一种氟唑菌酰羟胺的制备方法
GB201818113D0 (en) * 2018-11-06 2018-12-19 Syngenta Participations Ag Process
GB201818117D0 (en) * 2018-11-06 2018-12-19 Syngenta Participations Ag Enantioselective process
GB201821036D0 (en) 2018-12-21 2019-02-06 Syngenta Participations Ag Nematicidal compositions
EP4280879A1 (en) 2021-01-22 2023-11-29 Syngenta Crop Protection AG Method for the control or suppression of phytopathogenic bacteria
CN115703701B (zh) * 2021-08-16 2024-06-25 上海晓明检测技术服务有限公司 一种微通道连续合成1-(2,4,6-三氯-苯基)-丙-2-酮的方法
TW202412626A (zh) 2022-08-16 2024-04-01 瑞士商先正達農作物保護股份公司 新用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1298349B1 (it) * 1996-05-29 2000-01-05 Alfa Chem Ital Processo per la produzione di 1 - (3-trifluorometil) fenil-propan- 2-one intermedio nella sintesi della fenfluramina
WO2000034229A1 (en) * 1998-12-10 2000-06-15 Bayer Aktiengesellschaft Process for the preparation of strobilurin intermediates
US7683092B2 (en) * 2005-03-10 2010-03-23 Merck Sharp & Dohme Corp. Crystalline forms of antidiabetic compounds
EA020376B1 (ru) * 2008-12-05 2014-10-30 Зингента Партисипейшнс Аг Новые фунгицидно активные пиразолкарбоксамиды
EP2592931A4 (en) * 2010-07-13 2013-12-11 Syngenta Participations Ag SAFENER COMPOSITIONS AND METHOD FOR REDUCING MYCOTOXINES

Also Published As

Publication number Publication date
HRP20160001T1 (hr) 2016-02-12
AU2013225123B2 (en) 2016-10-20
US20150018562A1 (en) 2015-01-15
KR20140138154A (ko) 2014-12-03
CN104144914B (zh) 2016-03-02
CN104144914A (zh) 2014-11-12
MX2014009948A (es) 2014-11-12
CA2863467A1 (en) 2013-09-06
JP6078563B2 (ja) 2017-02-08
AU2013225123A1 (en) 2014-09-18
IL233937A0 (en) 2014-09-30
HUE026564T2 (hu) 2016-06-28
US9051272B2 (en) 2015-06-09
IL233937A (en) 2016-04-21
EP2819997B1 (en) 2015-10-28
KR102031809B1 (ko) 2019-10-14
DK2819997T3 (en) 2016-01-18
ES2558586T3 (es) 2016-02-05
TWI491594B (zh) 2015-07-11
JP2015508794A (ja) 2015-03-23
WO2013127764A1 (en) 2013-09-06
AR090172A1 (es) 2014-10-22
BR112014020556B1 (pt) 2019-11-26
PL2819997T3 (pl) 2016-03-31
CO7051031A2 (es) 2014-09-10
TW201348209A (zh) 2013-12-01
CA2863467C (en) 2020-03-10
EP2819997A1 (en) 2015-01-07
ZA201405823B (en) 2015-11-25

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