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AR002282A1 - Polipeptidos utiles para detectar y/o tratar infestaciones con t. cruzi, composiciones farmaceuticas formuladas con dichos polipeptidos; equipos queincluyen dichos polipeptidos para el diagnostico de dichas infecciones, dna, vectores y celulas recombinantes transformadas con dicho dna. - Google Patents

Polipeptidos utiles para detectar y/o tratar infestaciones con t. cruzi, composiciones farmaceuticas formuladas con dichos polipeptidos; equipos queincluyen dichos polipeptidos para el diagnostico de dichas infecciones, dna, vectores y celulas recombinantes transformadas con dicho dna.

Info

Publication number
AR002282A1
AR002282A1 ARP960101762A AR10176296A AR002282A1 AR 002282 A1 AR002282 A1 AR 002282A1 AR P960101762 A ARP960101762 A AR P960101762A AR 10176296 A AR10176296 A AR 10176296A AR 002282 A1 AR002282 A1 AR 002282A1
Authority
AR
Argentina
Prior art keywords
polypeptides
dna
infestations
cruzi
vectors
Prior art date
Application number
ARP960101762A
Other languages
English (en)
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of AR002282A1 publication Critical patent/AR002282A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se trata de nuevos péptidos para tratar y/o detectar infestaciones con T. Cruzi, caracterizados porque comprenden, al menos 7 restos consecutivos de lafracción SEQ ID NO: 1 entre la lisina al resto 137 y la alanina al resto 247, o variantesantigén icas de los mismos, que difieren solamente en sustituciones omodificaciones conservativas, con la condición de que el polipéptido no contenga mas de cinco restos consecutivos de la porción SEQ ID NO: 1 entre elaminoácido 1 y elaminoácido 136 . También se proponen composiciones farmacéuticas para dichas infestaciones y equipos para el diagnóstico de dichasinfestaciones. Se incluyen además células transformadas con vectores que comprenden el DNAcorrespondiente a dichos polipéptidos.
ARP960101762A 1995-03-14 1996-03-15 Polipeptidos utiles para detectar y/o tratar infestaciones con t. cruzi, composiciones farmaceuticas formuladas con dichos polipeptidos; equipos queincluyen dichos polipeptidos para el diagnostico de dichas infecciones, dna, vectores y celulas recombinantes transformadas con dicho dna. AR002282A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/403,379 US5756662A (en) 1995-03-14 1995-03-14 Compounds and methods for the detection of T. cruzi infection

Publications (1)

Publication Number Publication Date
AR002282A1 true AR002282A1 (es) 1998-03-11

Family

ID=23595554

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960101762A AR002282A1 (es) 1995-03-14 1996-03-15 Polipeptidos utiles para detectar y/o tratar infestaciones con t. cruzi, composiciones farmaceuticas formuladas con dichos polipeptidos; equipos queincluyen dichos polipeptidos para el diagnostico de dichas infecciones, dna, vectores y celulas recombinantes transformadas con dicho dna.

Country Status (13)

Country Link
US (2) US5756662A (es)
EP (1) EP0815450B1 (es)
JP (1) JPH11502923A (es)
AR (1) AR002282A1 (es)
AT (1) ATE220797T1 (es)
AU (1) AU5362696A (es)
BR (1) BR9607531A (es)
CA (1) CA2215104A1 (es)
DE (1) DE69622385T2 (es)
DK (1) DK0815450T3 (es)
ES (1) ES2180754T3 (es)
PT (1) PT815450E (es)
WO (1) WO1996029605A2 (es)

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US5756662A (en) * 1995-03-14 1998-05-26 Corixa Corporation Compounds and methods for the detection of T. cruzi infection
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US7833534B2 (en) * 2006-04-10 2010-11-16 Infectious Disease Research Institute Compounds and methods for diagnosis and treatment of leishmaniasis
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Also Published As

Publication number Publication date
EP0815450B1 (en) 2002-07-17
US5942403A (en) 1999-08-24
DE69622385D1 (de) 2002-08-22
BR9607531A (pt) 1998-01-06
EP0815450A2 (en) 1998-01-07
DE69622385T2 (de) 2003-03-06
US5756662A (en) 1998-05-26
AU5362696A (en) 1996-10-08
JPH11502923A (ja) 1999-03-09
ATE220797T1 (de) 2002-08-15
MX9707020A (es) 1998-06-30
WO1996029605A3 (en) 1996-11-21
DK0815450T3 (da) 2002-10-28
PT815450E (pt) 2002-12-31
CA2215104A1 (en) 1996-09-26
WO1996029605A2 (en) 1996-09-26
ES2180754T3 (es) 2003-02-16

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