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AR000394A2 - Preparación de intermediarios de beta-metil carbapenem y compuestos intermediarios para su exclusivouso en dicha preparación - Google Patents

Preparación de intermediarios de beta-metil carbapenem y compuestos intermediarios para su exclusivouso en dicha preparación

Info

Publication number
AR000394A2
AR000394A2 AR33470595A AR33470595A AR000394A2 AR 000394 A2 AR000394 A2 AR 000394A2 AR 33470595 A AR33470595 A AR 33470595A AR 33470595 A AR33470595 A AR 33470595A AR 000394 A2 AR000394 A2 AR 000394A2
Authority
AR
Argentina
Prior art keywords
preparation
intermediates
beta
exclusive use
methyl carbapenem
Prior art date
Application number
AR33470595A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Priority to AR33470595A priority Critical patent/AR000394A2/es
Publication of AR000394A2 publication Critical patent/AR000394A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un procedimiento para preparar un intermediario de beta-metil carbapenem de fórmula (VI) a partir de un compuestode fórmula (I), donde R y P son grupos protectores, R1 es un éster de ácido metilmalónico yNu es un grupo nucleofílico. También se dan a conocerintermediarios para el procedimiento.
AR33470595A 1992-09-18 1995-12-19 Preparación de intermediarios de beta-metil carbapenem y compuestos intermediarios para su exclusivouso en dicha preparación AR000394A2 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AR33470595A AR000394A2 (es) 1992-09-18 1995-12-19 Preparación de intermediarios de beta-metil carbapenem y compuestos intermediarios para su exclusivouso en dicha preparación

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94718692A 1992-09-18 1992-09-18
AR33470595A AR000394A2 (es) 1992-09-18 1995-12-19 Preparación de intermediarios de beta-metil carbapenem y compuestos intermediarios para su exclusivouso en dicha preparación

Publications (1)

Publication Number Publication Date
AR000394A2 true AR000394A2 (es) 1997-06-18

Family

ID=25485687

Family Applications (1)

Application Number Title Priority Date Filing Date
AR33470595A AR000394A2 (es) 1992-09-18 1995-12-19 Preparación de intermediarios de beta-metil carbapenem y compuestos intermediarios para su exclusivouso en dicha preparación

Country Status (24)

Country Link
US (2) US6242596B1 (es)
EP (1) EP0589626B1 (es)
JP (1) JP3252032B2 (es)
CN (2) CN1066438C (es)
AR (1) AR000394A2 (es)
AT (1) ATE214048T1 (es)
AU (1) AU667571B2 (es)
CA (1) CA2106248A1 (es)
CZ (1) CZ286267B6 (es)
DE (1) DE69331650T2 (es)
DK (1) DK0589626T3 (es)
ES (1) ES2173884T3 (es)
FI (1) FI951212L (es)
HK (1) HK1008336A1 (es)
HR (1) HRP931199B1 (es)
MX (1) MX9305715A (es)
PT (1) PT589626E (es)
RO (1) RO116087B1 (es)
RU (1) RU2130927C1 (es)
SI (1) SI9300486B (es)
SK (1) SK282164B6 (es)
TW (1) TW406073B (es)
UA (1) UA50705C2 (es)
WO (1) WO1994006764A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1061233C (zh) * 1996-12-13 2001-01-31 高琳 一种保健口服液及其生产工艺
KR100335848B1 (ko) * 2000-03-31 2002-05-08 윤재승 아제티디논 유도체, 그 제조방법 및 이를 이용한1-β-알킬아제티디논의 제조방법
US6625203B2 (en) * 2001-04-30 2003-09-23 Interdigital Technology Corporation Fast joint detection
EP1878829A1 (de) 2006-07-12 2008-01-16 Papierfabriken Cham-Tenero AG Beschichtetes Trägerpapier

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001705A1 (en) * 1980-11-13 1982-05-27 Takeda Chemical Industries Ltd 4-substituted-2-oxoazetidine derivatives and process for their preparation
AU548727B2 (en) * 1981-03-12 1986-01-02 Gruppo Lepetit S.P.A. Beta-lactam acetic acid derivatives
US4576747A (en) * 1984-05-07 1986-03-18 The Upjohn Company Isocyanato-azetidinediones
EP0177454B1 (de) * 1984-10-04 1988-12-21 Ciba-Geigy Ag Silane, Verfahren zu deren Herstellung und deren Verwendung
DE3879791T2 (de) 1987-07-17 1993-10-14 Merck & Co Inc 4-Substituierte 3-Oxobutanoat-Esterderivate.
ES2054604T3 (es) * 1987-09-22 1995-12-01 Shionogi & Co Intermedios alquenilsililazetidinona para carbapenemes.
US4992545A (en) * 1989-09-20 1991-02-12 Eli Lilly And Company Process for preparing 4-substituted azetidinones
EP0546742B1 (en) * 1991-12-09 2001-06-20 Takasago International Corporation 4-(1,1-Dialkoxycarbonyl-alkyl)azetidin-2-one derivatives and synthesis of 4-(1-carboxy-alkyl)azetidin-2-one derivatives therefrom

Also Published As

Publication number Publication date
EP0589626B1 (en) 2002-03-06
AU667571B2 (en) 1996-03-28
ATE214048T1 (de) 2002-03-15
DE69331650T2 (de) 2002-08-22
UA50705C2 (uk) 2002-11-15
CZ34695A3 (en) 1995-11-15
CN1066438C (zh) 2001-05-30
CN1232035A (zh) 1999-10-20
CN1101397C (zh) 2003-02-12
PT589626E (pt) 2002-07-31
FI951212A0 (fi) 1995-03-15
SK34995A3 (en) 1995-08-09
JP3252032B2 (ja) 2002-01-28
US5654424A (en) 1997-08-05
CZ286267B6 (cs) 2000-03-15
DE69331650D1 (de) 2002-04-11
SK282164B6 (sk) 2001-11-06
DK0589626T3 (da) 2002-04-02
FI951212L (fi) 1995-03-15
RU95108544A (ru) 1997-01-10
CA2106248A1 (en) 1994-03-19
SI9300486B (sl) 2003-02-28
JPH06192220A (ja) 1994-07-12
HRP931199B1 (en) 2003-02-28
ES2173884T3 (es) 2002-11-01
HK1008336A1 (en) 1999-05-07
AU4743393A (en) 1994-03-24
US6242596B1 (en) 2001-06-05
TW406073B (en) 2000-09-21
MX9305715A (es) 1994-03-31
SI9300486A (en) 1994-03-31
RO116087B1 (ro) 2000-10-30
RU2130927C1 (ru) 1999-05-27
HRP931199A2 (en) 1995-02-28
EP0589626A1 (en) 1994-03-30
CN1092763A (zh) 1994-09-28
WO1994006764A1 (en) 1994-03-31

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