Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Genetics and Genomics

    DNA replication in primary hepatocytes without the six-subunit ORC

    Róża K Przanowska, Yuechuan Chen ... Anindya Dutta
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Immunology and Inflammation

    Layilin Regulates Treg Motility and Suppressive Capacity in Skin

    Victoire Gouirand, Sean Clancy ... Michael D Rosenblum
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cancer Biology
    2. Cell Biology

    Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis

    Zuzana Outla, Gizem Oyman-Eyrilmez ... Martin Gregor
    Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy resistance.
    1. Cell Biology
    2. Medicine

    PCBP2 as an intrinsic agi ng factor regulates the senescence of hBMSCs through the ROS-FGF2 signaling axis

    Pengbo Chen, Bo Li ... Xinfeng Zheng
    The intrinsic factor of cell senescence, PCBP2, was identified by unlabeled quantitative proteomics, and its biological role in in vitro replication senescence of human bone marrow mesenchymal stromal cells was characterized in vitro.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Single-nucleus transcriptomics reveal the cytological mechanism of conjugated linoleic acids in regulating intramuscular fat deposition

    Liyi Wang, Shiqi Liu ... Tizhong Shan
    The cytological mechanism of conjugated linoleic acids regulates fat infiltration in skeletal muscles based on pig models via using single-nucleus transcriptomics.
    1. Cell Biology
    2. Cancer Biology

    Cell crowding activates pro-invasive mechanotransduction pathway in high-grade DCIS via TRPV4 inhibition and cell volume reduction

    Xiangning Bu, Nathanael Ashby ... Inhee Chung
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Plant Biology

    ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability

    Baihong Zhang, Shuqin Huang ... Wenli Chen
    ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4.
    1. Cell Biology
    2. Cancer Biology

    Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer

    Chong Zhang, Zuoyan Zhang ... Yangling Li
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    The Kv2.2 channel mediates the inhibition of prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β-cells

    Chengfang Pan, Ying Liu ... Changlong Hu
    Prostaglandin E2 inhibits Kv2.2 channels via the EP2/4-PKA signaling pathway, leading to decreased glucose-stimulated action potential firing and insulin secretion in normal pancreatic β-cells.
    1. Cell Biology

    Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction

    Xiaoning Gao, WuYan Guo ... Jun Kang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    The Institute of Photonic Sciences, Spain
  3. Silke Hauf
    Virginia Tech, United States
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