Cancer Biology

Latest articles

1. 1. Cancer Biology

   Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia model

   Tristan Gicquel, Fabio Marchiano ... Alice Carrier

   Pancreatic cancer-associated muscle atrophy is characterized by strong mitochondrial metabolic defects that are not limited to carbohydrate, protein, and redox metabolism, but also concern lipid and nucleic acid metabolisms.
2. 1. Cell Biology
   2. Cancer Biology

   Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis

   Zuzana Outla, Gizem Oyman-Eyrilmez ... Martin Gregor
3. 1. Cell Biology
   2. Cancer Biology

   Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer

   Chong Zhang, Zuoyan Zhang ... Yangling Li
4. 1. Cell Biology
   2. Cancer Biology

   Image-based identification and isolation of micronucleated cells to dissect cellular consequences

   Lucian DiPeso, Sriram Pendyala ... Emily M Hatch
5. 1. Computational and Systems Biology
   2. Cancer Biology

   Unveiling the influence of tumor and immune signatures on immune checkpoint therapy in advanced lung cancer

   Nayoung Kim, Sehhoon Park ... Myung-Ju Ahn
6. 1. Cancer Biology

   Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism

   Weijie Wu, Miao Yu ... Hongquan Zhang
7. 1. Cancer Biology

   A new potential strategy for cutaneous squamous cell carcinoma treatment by generating serum-based antibodies from tumor-exposed mice

   Zheng Liu

   The new cancer treatment strategy reduces the volume of mouse cutaneous squamous cell carcinoma and reverses the expression of tumor marker proteins by stimulating the production of serum-based antibodies.
8. 1. Computational and Systems Biology
   2. Cancer Biology

   Is tumor mutational burden predictive of response to immunotherapy?

   Carino Gurjao, Dina Tsukrov ... Leonid A Mirny
9. 1. Cancer Biology

   Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

   Hyungtai Sim, Hyun Jung Park ... Murim Choi
10. 1. Cancer Biology
    2. Cell Biology

    Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment

    Alexandra Urbancokova, Terezie Hornofova ... Pavla Vasicova

    Chemotherapeutics altering DNA topology evoke RNA polymerase I inhibition, rDNA damage and consequent formation of PNAs that segregate persistent rDNA lesions from the active nucleolus, with implications for rDNA maintenance and design of new cancer treatment strategies targeting rDNA repair.