Regulation of WRN helicase activity in human base excision repair (Q45072750)

9 December 2017

title

Regulation of WRN helicase activity in human base excision repair (English)

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9 December 2017

Vilhelm A Bohr

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9 December 2017

Byungchan Ahn

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9 December 2017

Jeanine A Harrigan

series ordinal

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9 December 2017

Fred E Indig

series ordinal

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9 December 2017

David M Wilson

series ordinal

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9 December 2017

language of work or name

English

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publication date

22 September 2004

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Journal of Biological Chemistry

9 December 2017

published in

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9 December 2017

volume

279

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9 December 2017

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9 December 2017

page(s)

53465-53474

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Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations

9 December 2017

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Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair

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Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

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Molecular mechanism of PCNA-dependent base excision repair

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Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA

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DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

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Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

21 January 2018

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21 January 2018

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Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 January 2018

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21 January 2018

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The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity

21 January 2018

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The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity

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Werner syndrome protein contains three structure-specific DNA binding domains

21 January 2018

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21 January 2018

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Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins

21 January 2018

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Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

21 January 2018

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Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion

21 January 2018

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DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP

21 January 2018

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 January 2018

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A quantitative model of human DNA base excision repair. I. Mechanistic insights

21 January 2018

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Two distinct human DNA diesterases that hydrolyze 3′-blocking deoxyribose fragments from oxidized DNA

21 January 2018

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21 January 2018

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The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.

21 January 2018

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21 January 2018

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Acetylation of human AP-endonuclease 1, a critical enzyme in DNA repair and transcription regulation

21 January 2018

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The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

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AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair

21 January 2018

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Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase

21 January 2018

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Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M409624200

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9 December 2017

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