ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. (Q40414334)

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12 January 2020

title

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin (English)

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12 January 2020

Kenneth K Teng

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ORCID Public Data File 2021

author name string

Henry K Teng

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12 January 2020

Ramee Lee

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Saundrene Wright

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Seema Tevar

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Pouneh Kermani

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12 January 2020

Risa Torkin

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Zhe-Yu Chen

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Francis S Lee

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Rosemary T Kraemer

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Barbara L Hempstead

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language of work or name

English

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publication date

1 June 2005

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12 January 2020

published in

Journal of Neuroscience

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volume

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issue

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12 January 2020

page(s)

5455-5463

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Functionally antagonistic interactions between the TrkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation

12 January 2020

cites work

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12 December 2020

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

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12 December 2020

Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

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12 December 2020

BDNF regulates eating behavior and locomotor activity in mice

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12 December 2020

p75(NTR) mediates neurotrophin-induced apoptosis of vascular smooth muscle cells

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12 December 2020

Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor

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12 December 2020

Contribution of BDNF-mediated inhibition in patterning avian skin innervation

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12 December 2020

The pro-sequence facilitates folding of human nerve growth factor from Escherichia coli inclusion bodies

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12 December 2020

Neurotrophins: roles in neuronal development and function

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12 December 2020

Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase

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12 December 2020

Regulation of cell survival by secreted proneurotrophins

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12 December 2020

Specificity in Trk receptor:neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5

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12 December 2020

A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor

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12 December 2020

Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases

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12 December 2020

c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

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12 December 2020

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

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12 December 2020

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

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12 December 2020

Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line

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12 December 2020

The neurotrophin receptor p75NTR as a positive modulator of myelination

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12 December 2020

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

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12 December 2020

Regional expression of p75NTR contributes to neurotrophin regulation of cerebellar patterning

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12 December 2020

Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease.

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12 December 2020

Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin

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12 December 2020

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

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12 December 2020

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance.

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12 December 2020

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

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12 December 2020

Sortilin is essential for proNGF-induced neuronal cell death

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12 December 2020

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

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12 December 2020

p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity.

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12 December 2020

Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons.

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12 December 2020

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

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12 December 2020

Functional organization of the sortilin Vps10p domain

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12 December 2020

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

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12 December 2020

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

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12 December 2020

Screening of adrenal medullary neuropeptides for putative neurotrophic effects

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12 December 2020

Two conserved domains in the NGF propeptide are necessary and sufficient for the biosynthesis of correctly processed and biologically active NGF.

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12 December 2020

Rapid isolation of the 7S-nerve growth factor complex and its subunits from murine submaxillary glands and saliva

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12 December 2020

p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF

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12 December 2020

The biosynthesis of neurotrophin heterodimers by transfected mammalian cells

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12 December 2020

Characterisation of Neurotrophin Dimers and Monomers

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12 December 2020

Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth.

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12 December 2020

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

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12 December 2020

Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival.

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12 December 2020

Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding

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12 December 2020

10.1523/JNEUROSCI.5123-04.2005

Identifiers

DOI

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12 January 2020

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PubMed publication ID

15930396

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