ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. (Q40414334)

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scientific article published on June 2005

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English	ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.	scientific article published on June 2005

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12 January 2020

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin (English)

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12 January 2020

apoptotic process

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12 January 2020

Ramiro D. Almeida

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12 January 2020

Kenneth K. Teng

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Kenneth K Teng

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ORCID Public Data File 2021

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Henry K Teng

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12 January 2020

Ramee Lee

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12 January 2020

Saundrene Wright

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12 January 2020

Seema Tevar

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12 January 2020

Pouneh Kermani

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12 January 2020

Risa Torkin

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12 January 2020

Zhe-Yu Chen

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12 January 2020

Francis S Lee

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12 January 2020

Rosemary T Kraemer

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12 January 2020

Barbara L Hempstead

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12 January 2020

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1 June 2005

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12 January 2020

Journal of Neuroscience

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12 January 2020

25

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12 January 2020

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12 January 2020

5455-5463

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12 January 2020

Functionally antagonistic interactions between the TrkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF regulates eating behavior and locomotor activity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p75(NTR) mediates neurotrophin-induced apoptosis of vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of BDNF-mediated inhibition in patterning avian skin innervation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pro-sequence facilitates folding of human nerve growth factor from Escherichia coli inclusion bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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Neurotrophins: roles in neuronal development and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cell survival by secreted proneurotrophins

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https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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Specificity in Trk receptor:neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurotrophin receptor p75NTR as a positive modulator of myelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional expression of p75NTR contributes to neurotrophin regulation of cerebellar patterning

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

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Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sortilin is essential for proNGF-induced neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional organization of the sortilin Vps10p domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening of adrenal medullary neuropeptides for putative neurotrophic effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two conserved domains in the NGF propeptide are necessary and sufficient for the biosynthesis of correctly processed and biologically active NGF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid isolation of the 7S-nerve growth factor complex and its subunits from murine submaxillary glands and saliva

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthesis of neurotrophin heterodimers by transfected mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of Neurotrophin Dimers and Monomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/15930396

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5123-04.2005

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15930396%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15930396%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15930396%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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