Sirtuins mediate mammalian metabolic responses to nutrient availability (Q37976307)

26 August 2017

title

Sirtuins mediate mammalian metabolic responses to nutrient availability (English)

1 reference

26 August 2017

Angeliki Chalkiadaki

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26 August 2017

Leonard Guarente

series ordinal

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26 August 2017

publication date

17 January 2012

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Nature Reviews Endocrinology

26 August 2017

published in

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26 August 2017

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26 August 2017

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26 August 2017

page(s)

287-296

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

26 August 2017

cites work

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Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin

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Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

31 March 2020

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Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

31 March 2020

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The SirT3 divining rod points to oxidative stress

31 March 2020

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Structure of a Sir2 enzyme bound to an acetylated p53 peptide

31 March 2020

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Structure of the histone deacetylase SIRT2

31 March 2020

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Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

31 March 2020

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Role of NAD(+) in the deacetylase activity of the SIR2-like proteins

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Interplay of circadian clocks and metabolic rhythms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Tissue-specific regulation of SIRT1 by calorie restriction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Effects of nicotinamide on NAD and poly(ADP-ribose) metabolism in DNA-damaged human lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

PARP-2 regulates SIRT1 expression and whole-body energy expenditure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1: recent lessons from mouse models.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Fuel metabolism in starvation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

STAT3 inhibition of gluconeogenesis is downregulated by SirT1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

FXR: a promising target for the metabolic syndrome?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

miR-34a repression of SIRT1 regulates apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Autophagy in the cellular energetic balance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Autophagy in health and disease: a double-edged sword

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The role of autophagy during the early neonatal starvation period

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Autophagy in the Pathogenesis of Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The insulin resistance syndrome: definition and dietary approaches to treatment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Resveratrol improves health and survival of mice on a high-calorie diet

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SirT1 gain of function increases energy efficiency and prevents diabetes in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirt1 protects against high-fat diet-induced metabolic damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Insulin sensitivity: modulation by nutrients and inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Hypothalamic Sirt1 regulates food intake in a rodent model system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 Promotes the Central Adaptive Response to Diet Restriction through Activation of the Dorsomedial and Lateral Nuclei of the Hypothalamus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Regulation of angiogenesis by oxygen and metabolism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 controls endothelial angiogenic functions during vascular growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirt1 contributes critically to the redox-dependent fate of neural progenitors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Histone methyl transferases and demethylases; can they link metabolism and transcription?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Oxygen sensors at the crossroad of metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Understanding the Warburg effect: the metabolic requirements of cell proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Substrate-specific activation of sirtuins by resveratrol

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

RETRACTED: Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

DBC1 is a negative regulator of SIRT1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Negative regulation of the deacetylase SIRT1 by DBC1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Phosphorylation regulates SIRT1 function.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

JNK1 phosphorylates SIRT1 and promotes its enzymatic activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Calorie restriction--the SIR2 connection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Increase in activity during calorie restriction requires Sirt1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

SIRT1 transgenic mice show phenotypes resembling calorie restriction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2011.225

Sir2 links chromatin silencing, metabolism, and aging

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22249520

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MAR1-a Regulator of the HMa and HMalpha Loci in SACCHAROMYCES CEREVISIAE

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22249520

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRENDO.2011.225

1 reference

Dimensions Publication ID

26 August 2017

1043409171

0 references

1 reference