SIRT1 regulates circadian clock gene expression through PER2 deacetylation (Q24317933)

circadian regulation of gene expression

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Sirtuin 1

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Cryptochrome 1 (photolyase-like)

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Aryl hydrocarbon receptor nuclear translocator-like

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Period circadian clock 2

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Circadian locomotor output cycles kaput

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Gad Asher

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David Gatfield

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Markus Stratmann

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Hans Reinke

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Charna Dibner

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Florian Kreppel

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Raul Mostoslavsky

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Frederick W Alt

The tandem affinity purification (TAP) method: a general procedure of protein complex purification

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language of work or name

English

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publication date

25 July 2008

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published in

Cell

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volume

134

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issue

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page(s)

317-28

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cites work

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Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells

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Circadian regulator CLOCK is a histone acetyltransferase

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Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression

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Execution of the circadian negative feedback loop in Neurospora requires the ATP-dependent chromatin-remodeling enzyme CLOCKSWITCH.

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SIRT1 deacetylates and positively regulates the nuclear receptor LXR

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A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

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A serum shock induces circadian gene expression in mammalian tissue culture cells

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Posttranslational mechanisms regulate the mammalian circadian clock

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Coordinated transcription of key pathways in the mouse by the circadian clock

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The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

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Mammalian SIRT1 represses forkhead transcription factors

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The mammalian circadian clock

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Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus

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Circadian programs of transcriptional activation, signaling, and protein turnover revealed by microarray analysis of mammalian cells

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Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

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Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels

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Coordination of circadian timing in mammals

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Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

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Reciprocal regulation of haem biosynthesis and the circadian clock in mammals

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism

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CLOCK-mediated acetylation of BMAL1 controls circadian function

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Extensive and divergent circadian gene expression in liver and heart

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Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions

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CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock

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Metabolic cycles as an underlying basis of biological oscillations

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Post-translational modifications regulate the ticking of the circadian clock.

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A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo

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Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

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Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

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Mitogen-activated protein kinase phosphorylates and negatively regulates basic helix-loop-helix-PAS transcription factor BMAL1.

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The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon

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Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

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Histone acetyltransferase-dependent chromatin remodeling and the vascular clock

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SIRT1 shows no substrate specificity in vitro

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7 January 2021

SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein

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Sirtuins: the 'magnificent seven', function, metabolism and longevity

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A DNA-based method to assay total and infectious particle contents and helper virus contamination in high-capacity adenoviral vector preparations

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Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein

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Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

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Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP

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Molecular mechanisms of the biological clock in cultured fibroblasts

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Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

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NPAS2: an analog of clock operative in the mammalian forebrain

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

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PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator

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Circadian clock control by SUMOylation of BMAL1.

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The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period

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SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins

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7 January 2021

Entrainment of the circadian clock in the liver by feeding

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7 January 2021

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

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7 January 2021

Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation

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7 January 2021

Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation.

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7 January 2021

Metabolism and the control of circadian rhythms

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7 January 2021

The Sir2 family of protein deacetylases

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7 January 2021

Genetics of the mammalian circadian system: Photic entrainment, circadian pacemaker mechanisms, and posttranslational regulation

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7 January 2021

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

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7 January 2021

System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock

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7 January 2021