Role of endocrine and paracrine factors in the adaptation of bone to mechanical loading (Q37850710)

24 August 2017

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title

Role of endocrine and paracrine factors in the adaptation of bone to mechanical loading (English)

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24 August 2017

Gabriel L Galea

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Toshihiro Sugiyama

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Lee B Meakin

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Joanna S Price

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24 August 2017

Andrew Sunters

series ordinal

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24 August 2017

Lance E Lanyon

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24 August 2017

publication date

1 June 2011

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Current osteoporosis reports

24 August 2017

published in

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24 August 2017

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24 August 2017

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24 August 2017

page(s)

76-82

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Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice

24 August 2017

cites work

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12 December 2020

Regulation of bone metabolism by nuclear receptors

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12 December 2020

Parathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient mice

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12 December 2020

Control of bone mass and remodeling by PTH receptor signaling in osteocytes

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12 December 2020

Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones

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12 December 2020

Nuclear factor of activated T cells mediates fluid shear stress- and tensile strain-induced Cox2 in human and murine bone cells

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12 December 2020

PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase-3beta in osteoblastic Saos-2 cells

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12 December 2020

Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

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12 December 2020

Bone mass is preserved and cancellous architecture altered due to cyclic loading of the mouse tibia after orchidectomy.

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12 December 2020

Wnt signaling and the regulation of bone mass

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12 December 2020

Sclerostin and the regulation of bone formation: Effects in hip osteoarthritis and femoral neck fracture.

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12 December 2020

Timing of ibuprofen use and bone mineral density adaptations to exercise training.

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12 December 2020

A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction

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12 December 2020

Attenuated response to in vivo mechanical loading in mice with conditional osteoblast ablation of the connexin43 gene (Gja1).

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12 December 2020

Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

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12 December 2020

Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha

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12 December 2020

Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells.

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12 December 2020

Bone adaptation requires oestrogen receptor-α

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12 December 2020

Mechanical stress activates Smad pathway through PKCδ to enhance interleukin-11 gene transcription in osteoblasts

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12 December 2020

Regulation of circulating sclerostin levels by sex steroids in women and in men.

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12 December 2020

Parathyroid hormone signaling through low-density lipoprotein-related protein 6

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12 December 2020

Adaptation of connexin 43-hemichannel prostaglandin release to mechanical loading

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12 December 2020

Mechanical induction of PGE2 in osteocytes blocks glucocorticoid-induced apoptosis through both the β-catenin and PKA pathways

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12 December 2020

Impact of acute exercise on bone turnover and growth hormone/insulin-like growth factor axis in boys

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12 December 2020

Role for beta1 integrins in cortical osteocytes during acute musculoskeletal disuse.

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12 December 2020

Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice

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12 December 2020

Non-canonical Wnt signaling and N-cadherin related beta-catenin signaling play a role in mechanically induced osteogenic cell fate

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12 December 2020

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12 December 2020

PTH and PTHrP signaling in osteoblasts

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12 December 2020

Leptin receptor (Lepr) is a negative modulator of bone mechanosensitivity and genetic variations in Lepr may contribute to the differential osteogenic response to mechanical stimulation in the C57BL/6J and C3H/HeJ pair of mouse strains.

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12 December 2020

Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5

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12 December 2020

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

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12 December 2020

Beta-catenin levels influence rapid mechanical responses in osteoblasts

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12 December 2020

The response of bone to mechanical loading and disuse: fundamental principles and influences on osteoblast/osteocyte homeostasis.

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12 December 2020

Rescuing loading induced bone formation at senescence

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12 December 2020

Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss

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12 December 2020

Mechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female mice

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12 December 2020

Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells

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12 December 2020

Estrogen augments shear stress-induced signaling and gene expression in osteoblast-like cells via estrogen receptor-mediated expression of beta1-integrin

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12 December 2020

Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/beta-catenin signaling

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12 December 2020

Mechanical loading regulates NFATc1 and beta-catenin signaling through a GSK3beta control node

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12 December 2020

Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice

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12 December 2020

Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling

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12 December 2020

Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone

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12 December 2020

Thiazolidinediones induce osteocyte apoptosis and increase sclerostin expression

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12 December 2020

The matricellular protein periostin is required for sost inhibition and the anabolic response to mechanical loading and physical activity

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12 December 2020

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

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12 December 2020

10.1007/S11914-011-0050-7

Identifiers

DOI

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24 August 2017

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