Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding. (Q35458746)

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English	Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding.	scientific article

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23 February 2020

Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding (English)

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23 February 2020

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23 February 2020

Elizabeth Morris

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23 February 2020

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Edith Sim

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23 February 2020

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Nicola Laurieri

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23 February 2020

Isaac M Westwood

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23 February 2020

Amy Varney

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23 February 2020

Angela J Russell

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23 February 2020

Lesley A Stanley

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23 February 2020

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29 November 2014

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23 February 2020

BMC pharmacology & toxicology

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23 February 2020

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23 February 2020

68

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23 February 2020

From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258814

12 July 2018

Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1.

1 reference

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12 July 2018

Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery

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12 July 2018

A novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1

1 reference

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12 July 2018

Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over adversity

1 reference

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12 July 2018

Arylamine N-acetyltransferases: a structural perspective

1 reference

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12 July 2018

Arylamine N-acetyltransferase 1: a novel drug target in cancer development

1 reference

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12 July 2018

Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site

1 reference

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12 July 2018

Small molecule colorimetric probes for specific detection of human arylamine N-acetyltransferase 1, a potential breast cancer biomarker

1 reference

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12 July 2018

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

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12 July 2018

The SWISS-MODEL Repository and associated resources

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12 July 2018

Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.

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12 July 2018

Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258814

12 July 2018

Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase

1 reference

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12 July 2018

Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258814

12 July 2018

Structure and mechanism of arylamine N-acetyltransferases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4258814

12 July 2018

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

1 reference

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12 July 2018

Arylamine N-acetyltransferases: what we learn from genes and genomes

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12 July 2018

Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1).

1 reference

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12 July 2018

Identification and functional characterization of novel polymorphisms associated with the genes for arylamine N-acetyltransferases in mice

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12 July 2018

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid

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12 July 2018

Structure of arylamine N-acetyltransferase reveals a catalytic triad

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12 July 2018

Identification of amino acids imparting acceptor substrate selectivity to human arylamine acetyltransferases NAT1 and NAT2.

1 reference

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12 July 2018

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms

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12 July 2018

ESPript: analysis of multiple sequence alignments in PostScript

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12 July 2018

Chromosomal localization of human genes for arylamine N-acetyltransferase

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12 July 2018

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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12 July 2018

Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells

1 reference

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12 July 2018

Arylamine N-acetyltransferase in Balb/c mice: identification of a novel mouse isoenzyme by cloning and expression in vitro

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12 July 2018

N-acetylation pharmacogenetics

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12 July 2018

Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression

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12 July 2018

Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver

1 reference

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12 July 2018

Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening

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21 January 2018

Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice

1 reference

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21 January 2018

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases

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21 January 2018

NMR investigation of the catalytic mechanism of arylamine N-acetyltransferase from Salmonella typhimurium

1 reference

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21 January 2018

Molecular structure, infrared spectra, and photochemistry of isoniazid under cryogenic conditions

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21 January 2018

High-performance liquid-chromatographic determination of 5-aminosalicylic acid and its metabolites in blood plasma

1 reference

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21 January 2018

Hydralazine reduces the quantal size of secretory events by displacement of catecholamines from adrenomedullary chromaffin secretory vesicles

1 reference

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21 January 2018

Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice.

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26 September 2018

Protein Modeling by E-mail

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21 January 2018

New spectrophotometric and radiochemical assays for acetyl-CoA: arylamine N-acetyltransferase applicable to a variety of arylamines

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12 December 2020

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Cloned mouse N-acetyltransferases: enzymatic properties of expressed Nat-1 and Nat-2 gene products

1 reference

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12 December 2020

based on heuristic

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Structure-function studies of human arylamine N-acetyltransferases NAT1 and NAT2. Functional analysis of recombinant NAT1/NAT2 chimeras expressed in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of recombinant human N-acetyltransferase type 1 (NAT1) expressed in E. coli and characterization of its potential role in folate metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens

1 reference

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12 December 2020

based on heuristic

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Substrate selectivity of mouse N-acetyltransferases 1, 2, and 3 expressed in COS-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of dissociation constants of folic acid, methotrexate, and other photolabile pteridines by pressure-assisted capillary electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMR-based model reveals the structural determinants of mammalian arylamine N-acetyltransferase substrate specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biowaiver monographs for immediate release solid oral dosage forms: isoniazid

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arylamine N-acetyltransferase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arylamine N-acetyltransferases: from structure to function

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

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N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25432241

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10.1186/2050-6511-15-68

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23 February 2020

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23 February 2020

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23 February 2020

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