From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2 (Q28538748)

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scientific article (publication date: 2014)

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English	From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2	scientific article (publication date: 2014)

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scholarly article

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From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2 (English)

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7

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Edith Sim

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author name string

Nicola Laurieri

1

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Julien Dairou

2

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James E Egleton

3

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Lesley A Stanley

4

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Angela J Russell

5

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Jean-Marie Dupret

6

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Fernando Rodrigues-Lima

8

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publication date

2014

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9

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5

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e96370

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copyright license

Creative Commons Attribution 4.0 International

13 May 2014

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April 2022 Public Data File from Crossref

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Prospective virtual screening with Ultrafast Shape Recognition: the identification of novel inhibitors of arylamine N-acetyltransferases

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Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases

1 reference

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Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase

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19 March 2017

Generation and analysis of mice with a targeted disruption of the arylamine N-acetyltransferase type 2 gene

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The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid

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Structure of arylamine N-acetyltransferase reveals a catalytic triad

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Improved protein-ligand docking using GOLD

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Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1.

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5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion

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Arylamine N-acetyltransferases--from drug metabolism and pharmacogenetics to identification of novel targets for pharmacological intervention

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29 September 2017

Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker

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Improvement of the expression and purification of Mycobacterium tuberculosis arylamine N-acetyltransferase (TBNAT) a potential target for novel anti-tubercular agents

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Genes, environment, and orofacial clefting: N-acetyltransferase and folic acid

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Small molecule inhibition of arylamine N-acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells

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Changes in consensus arylamine N-acetyltransferase gene nomenclature

1 reference

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Arylamine N-acetyltransferase 1 expression in breast cancer cell lines: a potential marker in estrogen receptor-positive tumors

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Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism.

1 reference

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29 September 2017

Arylamine N-acetyltransferases.

1 reference

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29 September 2017

Structure and mechanism of arylamine N-acetyltransferases.

1 reference

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29 September 2017

Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.

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Identification and functional characterization of novel polymorphisms associated with the genes for arylamine N-acetyltransferases in mice

1 reference

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29 September 2017

Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos

1 reference

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Neural tube defects 1974-94--down but not out

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29 September 2017

Small molecule colorimetric probes for specific detection of human arylamine N-acetyltransferase 1, a potential breast cancer biomarker

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Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1.

1 reference

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Reversible inhibition of the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 by S-nitrosothiols

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Identification of amino acids imparting acceptor substrate selectivity to human arylamine acetyltransferases NAT1 and NAT2.

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Human placental transfer and metabolism of p-aminobenzoic acid.

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3 June 2018

Arylamine N-acetyltransferase activity of the human placenta.

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Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells

1 reference

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Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development and in adult mouse brain

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Ocular defects associated with a null mutation in the mouse arylamine N-acetyltransferase 2 gene.

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Only low levels of exogenous N-acetyltransferase can be achieved in transgenic mice.

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Confirmation of the role of N-acetyltransferase 2 in teratogen-induced cleft palate using transgenics and knockouts

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Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.

1 reference

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21 January 2018

Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.

1 reference

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21 January 2018

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0096370

21 January 2018

Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0096370

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An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases

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The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity

1 reference

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21 January 2018

Catalytic mechanism of hamster arylamine N-acetyltransferase 2.

1 reference

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21 January 2018

Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies

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21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0096370

21 January 2018

Promoter hypomethylation of the N-acetyltransferase 1 gene in breast cancer.

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27 November 2018

Developmental expression of N-acetyltransferases in C57BI/6 mice.

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27 November 2018

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1 reference

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inferred from PubMed ID database lookup

Purification of recombinant human N-acetyltransferase type 1 (NAT1) expressed in E. coli and characterization of its potential role in folate metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

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based on heuristic

inferred from PubMed ID database lookup

Elevated plasma homocysteine elicits an increase in antioxidant enzyme activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

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based on heuristic

inferred from PubMed ID database lookup

Acetyl coenzyme A: arylamine acetyltransferase. Measurement of the steady state concentration of the acetyl-enzyme intermediate

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

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based on heuristic

inferred from PubMed ID database lookup

New spectrophotometric and radiochemical assays for acetyl-CoA: arylamine N-acetyltransferase applicable to a variety of arylamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

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based on heuristic

inferred from PubMed ID database lookup

Arylamine N-acetyltransferase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

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based on heuristic

inferred from PubMed ID database lookup

N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

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based on heuristic

inferred from PubMed ID database lookup

Arylamine N-acetyltransferase in human red blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

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based on heuristic

inferred from PubMed ID database lookup

Loss of function polymorphisms in NAT1 protect against spina bifida

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arylamine N-acetyltransferases: from structure to function

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloned mouse N-acetyltransferases: enzymatic properties of expressed Nat-1 and Nat-2 gene products

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificity of acetyl coenzyme A synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetyltransferase in humans: development and tissue distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for genotyping murine arylamine N-acetyltransferase type 2 (NAT2): a gene expressed in preimplantation embryonic stem cells encoding an enzyme acetylating the folate catabolite p-aminobenzoylglutamate

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fragment consisting of the first 204 amino-terminal amino acids of human arylamine N-acetyltransferase one (NAT1) and the first transacetylation step of catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24823794

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0096370

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2014PLoSO...996370L

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