Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap. (Q34451308)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

title

Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

Ras GTPase activating protein 1 Dmel_CG6721

16 December 2019

main subject

Drosophila

0 references

1 reference

GOA release 2020-03-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

José A Botella

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Claudia Kiermayer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Pascale Feldmann

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

David A Hughes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Stephan Schneuwly

1 reference

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16 December 2019

publication date

1 January 2003

1 reference

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Molecular Biology of the Cell

16 December 2019

published in

1 reference

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16 December 2019

volume

1 reference

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16 December 2019

issue

1 reference

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16 December 2019

page(s)

241-250

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

The use of lead citrate at high pH as an electron-opaque stain in electron microscopy

16 December 2019

cites work

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The Ras branch of small GTPases: Ras family members don't fall far from the tree

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6 July 2018

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Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein

6 July 2018

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TIMELESS-dependent positive and negative autoregulation in the Drosophila circadian clock

6 July 2018

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Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

6 July 2018

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The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

6 July 2018

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

6 July 2018

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Dissecting the roles of the Drosophila EGF receptor in eye development and MAP kinase activation.

6 July 2018

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Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues

6 July 2018

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The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila.

6 July 2018

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Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap

6 July 2018

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The neurotrophic action and signalling of epidermal growth factor

6 July 2018

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The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm.

6 July 2018

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A modular misexpression screen in Drosophila detecting tissue-specific phenotypes

6 July 2018

1 reference

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Expression of Drosophila mushroom body mutations in alternative genetic backgrounds: a case study of the mushroom body miniature gene (mbm)

6 July 2018

1 reference

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Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase

6 July 2018

1 reference

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A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

6 July 2018

1 reference

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An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

6 July 2018

1 reference

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Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

6 July 2018

1 reference

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Programmed cell death and the control of cell survival: lessons from the nervous system

6 July 2018

1 reference

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Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

6 July 2018

1 reference

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Multiple Ras functions can contribute to mammalian cell transformation

6 July 2018

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Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila.

6 July 2018

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Inhibition of Drosophila EGF receptor activation by the secreted protein Argos.

6 July 2018

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

6 July 2018

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Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

6 July 2018

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The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages.

6 July 2018

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Tissue localization of Drosophila melanogaster ras transcripts during development

6 July 2018

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Alternative 5' exons and tissue-specific expression of the Drosophila EGF receptor homolog transcripts

6 July 2018

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P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila

6 July 2018

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Coordinately and differentially mutable activities of torpedo, the Drosophila melanogaster homolog of the vertebrate EGF receptor gene

6 July 2018

1 reference

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Developmental cell death: morphological diversity and multiple mechanisms

6 July 2018

1 reference

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rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster

6 July 2018

1 reference

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Characterization and spatial distribution of the ELAV protein duringDrosophila melanogaster development

6 July 2018

1 reference

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mip causes hyperinnervation of a retinotopic map in drosophila by excessive recruitment of R7 photoreceptor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140241

A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140241

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140241

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells

27 October 2018

1 reference

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Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport.

27 October 2018

1 reference

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Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140241

Sprouty, an intracellular inhibitor of Ras signaling.

27 October 2018

1 reference

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Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

27 October 2018

1 reference

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Ras promotes cell survival in Drosophila by downregulating hid expression

27 October 2018

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27 October 2018

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Screening of larval/pupal P-element induced lethals on the second chromosome in Drosophila melanogaster: clonal analysis and morphology of imaginal discs

27 October 2018

1 reference

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The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway

27 October 2018

1 reference

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The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140241

Glial membrane specializations and the compartmentalization of the lamina ganglionaris of the housefly compound eye.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140241

The fine structure of neuroglia in the lamina ganglionaris of the housefly, Musca domestica L.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140241

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12529440

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multiple extracellular signals are required for long-term oligodendrocyte survival

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12529440

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E02-05-0297

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PubMed publication ID

12529440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12529440%20AND%20SRC:MED&resulttype=core&format=json