Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial (Q29619615)

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scientific article (publication date: 24 July 2010)

Language	Label	Description	Also known as
English	Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial	scientific article (publication date: 24 July 2010)

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scholarly article

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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial (English)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20609468

30 April 2017

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Rita Schmutzler

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Schmutzler RK

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Jeffrey N Weitzel

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Weitzel JN

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author name string

Audeh MW

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Carmichael J

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Penson RT

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Friedlander M

4

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Powell B

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Bell-McGuinn KM

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Scott C

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Oaknin A

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Loman N

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Lu K

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Matulonis U

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Wickens M

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Tutt A

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language of work or name

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publication date

24 July 2010

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376

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9737

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245-51

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The PARP superfamily

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

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The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

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Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Brca1 controls homology-directed DNA repair

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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BRCA2 is required for homology-directed repair of chromosomal breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Preventing future cancers by testing women with ovarian cancer for BRCA mutations

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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BRCA1 and BRCA2 in breast cancer

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7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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The concept of synthetic lethality in the context of anticancer therapy

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Efficient Deletion of NormalBrca2-Deficient Intestinal Epithelium by Poly(ADP-Ribose) Polymerase Inhibition Models Potential Prophylactic Therapy

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https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to therapy caused by intragenic deletion in BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2810%2960893-8

7 January 2021

based on heuristic

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Identifiers

10.1016/S0140-6736(10)60893-8

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20609468

30 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20609468

30 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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