Removing obstacles in neuroscience drug discovery: the future path for animal models (Q28755229)

22 June 2017

1 reference

title

Removing obstacles in neuroscience drug discovery: the future path for animal models (English)

1 reference

22 June 2017

0 references

Christian Chiamulera

1 reference

22 June 2017

Athina Markou

1 reference

22 June 2017

Mark A Geyer

series ordinal

1 reference

22 June 2017

Mark Tricklebank

series ordinal

1 reference

22 June 2017

Thomas Steckler

series ordinal

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22 June 2017

language of work or name

English

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publication date

1 October 2008

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22 June 2017

published in

Neuropsychopharmacology

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22 June 2017

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22 June 2017

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22 June 2017

page(s)

74-89

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A collaborative knowledge base for cognitive phenomics

22 June 2017

cites work

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Acute ketamine administration alters the brain responses to executive demands in a verbal working memory task: an FMRI study.

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Neuronal systems underlying behaviors related to nicotine addiction: neural circuits and molecular genetics.

3 June 2018

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New developments in animal models of Alzheimer's disease

3 June 2018

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3 June 2018

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3 June 2018

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Factors controlling measures of anxiety and responses to novelty in the mouse

3 June 2018

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Considerations in the evaluation of surrogate endpoints in clinical trials. summary of a National Institutes of Health workshop

3 June 2018

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3 June 2018

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3 June 2018

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Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine

3 June 2018

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Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli.

3 June 2018

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Anxiogenic-like effect of acute and chronic fluoxetine on rats tested on the elevated plus-maze.

3 June 2018

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Neuropsychopharmacology at the new millennium: new industry directions

3 June 2018

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Neurobiological similarities in depression and drug dependence: a self-medication hypothesis

3 June 2018

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Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics.

3 June 2018

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Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies

3 June 2018

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3 June 2018

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The antipsychotic potential of subtype-selective 5-HT receptor ligands based on interactions with mesolimbic dopamine systems

3 June 2018

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3 June 2018

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3 June 2018

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Animal models of drug craving

3 June 2018

1 reference

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Use of the elevated plus maze in the search for novel anxiolytic agents

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Ketamine activates psychosis and alters limbic blood flow in schizophrenia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Norepinephrine in depressive reactions. A review

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Genetic Theorizing and Schizophrenia

3 June 2018

1 reference

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The biochemistry of affective disorders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

The use of a plus-maze to measure anxiety in the mouse

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Serotonin and its place in the pathogenesis of depression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

The early history of psychotherapeutic drugs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Exploratory behavior models of anxiety in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Negative schizophrenic symptomatology and the PCP (phencyclidine) model of schizophrenia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

The role of pharmacological profiling in safety assessment

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Clinical and biochemical aspects of depressive disorders: II. Transmitter/receptor theories

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Memory and cognitive function in man: Does the cholinergic system have a specific role?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Behavioural despair in rats: A new model sensitive to antidepressant treatments

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Selective loss of central cholinergic neurons in Alzheimer's disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

3 June 2018

1 reference

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The effects of sertraline and fluoxetine on anxiety in the elevated plus-maze test in mice.

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNPP.2008.173

Advanced behavioural screening: automated home cage ethology.

21 January 2018

1 reference

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Classification of anxiety and depressive disorders: problems and solutions.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Imaging beta-amyloid burden in aging and dementia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Cognitive-disruptive effects of the psychotomimetic phencyclidine and attenuation by atypical antipsychotic medications in rats.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study

27 November 2018

1 reference

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Safety, biodistribution, and dosimetry of 123I-IMPY: a novel amyloid plaque-imaging agent for the diagnosis of Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Psychiatric endophenotypes and the development of valid animal models.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

New approaches to measurement and treatment research to improve cognition in schizophrenia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Measurement and Treatment Research to Improve Cognition in Schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Paroxetine combined with a 5-HT(1A) receptor antagonist reversed reward deficits observed during amphetamine withdrawal in rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Inhibitory control in rats performing a stop-signal reaction-time task: effects of lesions of the medial striatum and d-amphetamine.

27 November 2018

1 reference

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Study of a new schizophrenomimetic drug; sernyl.

27 November 2018

1 reference

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Breaking the log-jam in treatment development for cognition in schizophrenia: NIMH perspective.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Characterization of the effects of bupropion on the reinforcing properties of nicotine and food in rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Summary of a National Institute of Mental Health workshop: developing animal models of anxiety disorders.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Serotonergic manipulations both potentiate and reduce brain stimulation reward in rats: involvement of serotonin-1A receptors

27 November 2018

1 reference

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Acute and chronic effects of gepirone and fluoxetine in rats tested in the elevated plus-maze: an ethological analysis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Cognitive dysfunction in schizophrenia: comparison of treatment with atypical antipsychotic agents and conventional neuroleptic drugs.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Ethological comparison of the effects of diazepam and acute/chronic imipramine on the behaviour of mice in the elevated plus-maze.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651739

Neurometabolic coupling in cerebral cortex reflects synaptic more than spiking activity

27 November 2018

1 reference

12 December 2020

Erice statement on drug innovation

1 reference

12 December 2020

The role of innovation in drug development

1 reference

12 December 2020

Toxicity of beta-amyloid vaccination in patients with Alzheimer's disease

1 reference

12 December 2020

Translational research in the pharmaceutical industry: from bench to bedside

1 reference

12 December 2020

Intermediate phenotypes in schizophrenia genetics redux: is it a no brainer?

1 reference

12 December 2020

The state of innovation in drug development

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12 December 2020

Relationship between the development of behavioral tolerance and the biodisposition of phencyclidine in mice

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12 December 2020

Identifiers

DOI

10.1038/NPP.2008.173

1 reference

Dimensions Publication ID

22 June 2017

1009868060

0 references

OpenCitations bibliographic resource ID

4415447

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4415447

1 reference