Advances in endophenotyping schizophrenia (Q30494518)

15 August 2017

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title

Advances in endophenotyping schizophrenia (English)

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15 August 2017

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Neal R Swerdlow

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15 August 2017

Gregory A Light

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15 August 2017

David L Braff

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15 August 2017

Nicholas J Schork

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15 August 2017

Tiffany A Greenwood

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15 August 2017

Investigators of the Consortium on the Genetics of Schizophrenia

series ordinal

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15 August 2017

language of work or name

English

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publication date

1 February 2008

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15 August 2017

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15 August 2017

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15 August 2017

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15 August 2017

11-18

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Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Replicating genotype-phenotype associations

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Schizophrenia: a common disease caused by multiple rare alleles

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

The endophenotype concept in psychiatric genetics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Molecular genetic studies of schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neuropsychological functioning in adolescents and young adults at genetic risk for schizophrenia and affective psychoses: results from the Harvard and Hillside Adolescent High Risk Studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Lower prepulse inhibition in children with the 22q11 deletion syndrome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Cognitive deficits in relatives of patients with schizophrenia: a meta-analysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Schizophrenia risk and paternal age: a potential role for de novo mutations in schizophrenia vulnerability genes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neurocognitive assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project schizophrenia trial: development, methodology, and rationale

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Verbal declarative memory dysfunction in schizophrenia: from clinical assessment to genetics and brain mechanisms

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

A unitary model of schizophrenia: Bleuler's "fragmented phrene" as schizencephaly

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

The endophenotype concept in psychiatry: etymology and strategic intentions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Childhood developmental abnormalities in schizophrenia: evidence from high-risk studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Principal stratification in causal inference

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Genetics of schizophrenia and the new millennium: progress and pitfalls

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: evidence of inhibitory deficits

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Attention, memory, and motor skills as childhood predictors of schizophrenia-related psychoses: the New York High-Risk Project.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Cognitive and behavioral precursors of schizophrenia.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Information processing and attention dysfunctions in schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Impaired attention, genetics, and the pathophysiology of schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Identification of the phenotype in psychiatric genetics.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Schizophrenic individuals' cognitive functioning and performance in interpersonal interactions and skills training procedures.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Deficits in sensory gating in schizophrenic patients and their relatives. Evidence obtained with auditory evoked responses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Genetic Theorizing and Schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neurobiological studies of sensory gating in schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

The continuous performance test, identical pairs version: II. Contrasting attentional profiles in schizophrenic and depressed patients.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Contributions of clinical neuropsychology to the study of schizophrenia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Sensorimotor gating and schizophrenia. Human and animal model studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Voluntary control of saccadic eye movements in patients with schizophrenic and affective disorders

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Glucose metabolic rate in normals and schizophrenics during the Continuous Performance Test assessed by positron emission tomography

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neuropsychological function in schizophrenia. Selective impairment in memory and learning

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: a magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

The person-key to understanding mental illness: towards a new dynamic psychiatry, III

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Prestimulus effects on human startle reflex in normals and schizophrenics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Successful multi-site measurement of antisaccade performance deficits in schizophrenia

14 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

P50 suppression among schizophrenia and normal comparison subjects: a methodological analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Auditory sensory gating, hippocampal volume, and catecholamine metabolism in schizophrenics and their siblings

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Preliminary evidence of an association between sensorimotor gating and distractibility in psychosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Information-processing deficits and thought disorder in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Relationships between neuropsychological and oculomotor measures in schizophrenia patients and normal controls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Attention Dysfunction in Chronic Schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

The effects of increasing resource demand on vigilance performance in adults with schizophrenia or developmental attentional/learning disorders: a preliminary study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Information processing and attentional functioning in the developmental course of schizophrenic disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Computerized neurocognitive scanning: II. The profile of schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Thalamic and amygdala-hippocampal volume reductions in first-degree relatives of patients with schizophrenia: an MRI-based morphometric analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Auditory working memory and Wisconsin Card Sorting Test performance in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Working memory in schizophrenia: transient "online" storage versus executive functioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Spatial working memory deficits in the relatives of schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Computerized neurocognitive scanning: I. Methodology and validation in healthy people

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Sequential genome-wide association studies for monitoring adverse events in the clinical evaluation of new drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJ.2051-5545.2008.TB00140.X

Memory impairment in schizophrenia: a meta-analysis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Schizophrenia: new phenes and new genes

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neurocognitive deficit in schizophrenia: a quantitative review of the evidence.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Attention deficits assessed by Continuous Performance Test and Span of Apprehension Test in Japanese schizophrenic patients

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Neurophysiological evidence for a defect in inhibitory pathways in schizophrenia: comparison of medicated and drug-free patients

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359727

Normalization of auditory physiology by cigarette smoking in schizophrenic patients

26 November 2018

1 reference

12 December 2020

Attentional and neuromotor functions of schizophrenics, schizoaffectives, and patients with other affective disorders

1 reference

12 December 2020

Distractibility in children vulnerable to psychopathology

1 reference

12 December 2020

Disorders of attention and perception in early schizophrenia

1 reference

12 December 2020

10.1002/J.2051-5545.2008.TB00140.X

Identifiers

DOI

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

18458787

1 reference