Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes (Q28611357)

3 February 2017

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Europe PubMed Central

title

Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes (English)

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3 February 2017

H. Shimano

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3 February 2017

publication date

1 November 2001

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Progress in Lipid Research

3 February 2017

published in

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3 February 2017

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3 February 2017

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3 February 2017

page(s)

439–452

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Dietary regulation of gene expression: enzymes involved in carbohydrate and lipid metabolism

3 February 2017

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Identification of Complexes between the COOH-terminal Domains of Sterol Regulatory Element-binding Proteins (SREBPs) and SREBP Cleavage-Activating Protein

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SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

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7 January 2021

Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

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7 January 2021

Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies

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7 January 2021

Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.

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7 January 2021

Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2.

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7 January 2021

Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins

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7 January 2021

Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning

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7 January 2021

Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

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7 January 2021

Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip

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7 January 2021

Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1.

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7 January 2021

Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase

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7 January 2021

Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells

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7 January 2021

Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain

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7 January 2021

Co-crystal structure of sterol regulatory element binding protein 1a at 2.3 A resolution

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7 January 2021

Sterol response element-binding protein 1c (SREBP1c) is involved in the polyunsaturated fatty acid suppression of hepatic S14 gene transcription

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https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways

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7 January 2021

Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene

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7 January 2021

Domains of transcription factor Sp1 required for synergistic activation with sterol regulatory element binding protein 1 of low density lipoprotein receptor promoter

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7 January 2021

Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid

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7 January 2021

Sterol regulatory element binding protein binds to a cis element in the promoter of the farnesyl diphosphate synthase gene

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7 January 2021

Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2.

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7 January 2021

Synergistic binding of sterol regulatory element-binding protein and NF-Y to the farnesyl diphosphate synthase promoter is critical for sterol-regulated expression of the gene

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7 January 2021

Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene.

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https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol

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7 January 2021

Promoter selective transcriptional synergy mediated by sterol regulatory element binding protein and Sp1: a critical role for the Btd domain of Sp1.

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7 January 2021

Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro

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7 January 2021

Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y.

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7 January 2021

Molecular cloning of the promoter for rat hepatic neutral cholesterol ester hydrolase: evidence for transcriptional regulation by sterols

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7 January 2021

Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase

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7 January 2021

Identification of diazepam-binding Inhibitor/Acyl-CoA-binding protein as a sterol regulatory element-binding protein-responsive gene

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7 January 2021

A critical role for cAMP response element-binding protein (CREB) as a Co-activator in sterol-regulated transcription of 3-hydroxy-3-methylglutaryl coenzyme A synthase promoter

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7 January 2021

Co-stimulation of promoter for low density lipoprotein receptor gene by sterol regulatory element-binding protein and Sp1 is specifically disrupted by the yin yang 1 protein

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7 January 2021

Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2

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7 January 2021

Genomic structure and chromosomal mapping of the human sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) gene

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7 January 2021

Orexin receptors are expressed in the adrenal medulla of the rat.

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7 January 2021

Sterol regulation of human fatty acid synthase promoter I requires nuclear factor-Y- and Sp-1-binding sites

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https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Transcriptional regulation of the ATP citrate-lyase gene by sterol regulatory element-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Nutrient regulation of gene expression by the sterol regulatory element binding proteins: increased recruitment of gene-specific coregulatory factors and selective hyperacetylation of histone H3 in vivo

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https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

YY1 is a negative regulator of transcription of three sterol regulatory element-binding protein-responsive genes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Yin Yang 1 Protein Negatively Regulates High-Density Lipoprotein Receptor Gene Transcription by Disrupting Binding of Sterol Regulatory Element Binding Protein to the Sterol Regulatory Element1

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2)

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https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation

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https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

1 reference

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7 January 2021

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

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7 January 2021

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7827%2801%2900010-8

7 January 2021

Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

1 reference

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7 January 2021

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

1 reference

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7 January 2021

Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N).

1 reference

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7 January 2021

Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver

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7 January 2021

Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein

1 reference

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7 January 2021

Oleate potentiates oxysterol inhibition of transcription from sterol regulatory element-1-regulated promoters and maturation of sterol regulatory element-binding proteins

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7 January 2021

Fish oil feeding decreases mature sterol regulatory element-binding protein 1 (SREBP-1) by down-regulation of SREBP-1c mRNA in mouse liver. A possible mechanism for down-regulation of lipogenic enzyme mRNAs

1 reference

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7 January 2021

A Crucial Role of Sterol Regulatory Element-binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids

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7 January 2021

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

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7 January 2021

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

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7 January 2021

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

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7 January 2021

Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.

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7 January 2021

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

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7 January 2021

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

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7 January 2021

Insulin effects on sterol regulatory-element-binding protein-1c (SREBP-1c) transcriptional activity in rat hepatocytes.

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7 January 2021

ADD-1 provides major new insight into the mechanism of insulin action

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7 January 2021

Induction of fatty acid synthase and S14 gene expression by glucose, xylitol and dihydroxyacetone in cultured rat hepatocytes is closely correlated with glucose 6-phosphate concentrations.

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7 January 2021

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

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7 January 2021

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

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7 January 2021

ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR.

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7 January 2021

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

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7 January 2021

Role of LXRs in control of lipogenesis

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7 January 2021

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

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7 January 2021

Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism

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7 January 2021

ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand

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7 January 2021

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

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7 January 2021

A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene

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7 January 2021

p38 mitogen-activated protein kinase down-regulates nitric oxide and up-regulates prostaglandin E2 biosynthesis stimulated by interleukin-1beta

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7 January 2021

Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter

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7 January 2021

Transcriptional activation of the stearoyl-CoA desaturase 2 gene by sterol regulatory element-binding protein/adipocyte determination and differentiation factor 1.

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7 January 2021

Induction of LPL gene expression by sterols is mediated by a sterol regulatory element and is independent of the presence of multiple E boxes

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7 January 2021

10.1016/S0163-7827(01)00010-8

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017