Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene (Q28584842)

31 January 2017

title

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene (English)

1 reference

Sterol regulatory element binding transcription factor 1

31 January 2017

main subject

1 reference

GOA release 2020-03-11

1 reference

H. Shimano

1 reference

31 January 2017

I. Shimomura

1 reference

31 January 2017

R. E. Hammer

1 reference

31 January 2017

J. Herz

1 reference

31 January 2017

J. L. Goldstein

1 reference

31 January 2017

M. S. Brown

1 reference

31 January 2017

J. D. Horton

1 reference

31 January 2017

language of work or name

English

0 references

publication date

15 October 1997

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Journal of Clinical Investigation

31 January 2017

published in

1 reference

31 January 2017

volume

100

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31 January 2017

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31 January 2017

page(s)

2115–2124

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

31 January 2017

cites work

1 reference

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Structure of the human gene encoding sterol regulatory element binding protein 2 (SREBF2)

17 March 2017

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Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

17 March 2017

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Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

17 March 2017

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Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1)

17 March 2017

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17 March 2017

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SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

17 March 2017

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Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13

17 March 2017

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29 September 2017

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Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

7 April 2017

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Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

29 September 2017

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29 September 2017

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29 September 2017

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Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse

29 September 2017

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29 September 2017

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29 September 2017

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3 June 2018

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Three different rearrangements in a single intron truncate sterol regulatory element binding protein-2 and produce sterol-resistant phenotype in three cell lines. Role of introns in protein evolution

3 June 2018

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3 June 2018

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