Development and cancer of the cerebellum (Q28305235)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

review article

1 reference

title

Development and cancer of the cerebellum (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Mary E Hatten

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

1 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

published in

Trends in Neurosciences

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

134-142

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

The genetic landscape of the childhood cancer medulloblastoma

22 January 2020

cites work

1 reference

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Subtypes of medulloblastoma have distinct developmental origins

20 March 2017

1 reference

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The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma

20 March 2017

1 reference

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Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

20 March 2017

1 reference

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The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors

20 March 2017

1 reference

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The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

20 March 2017

1 reference

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Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

20 March 2017

1 reference

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Timing neurogenesis and differentiation: insights from quantitative clonal analyses of cerebellar granule cells

20 March 2017

1 reference

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

20 March 2017

1 reference

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The 2007 WHO classification of tumours of the central nervous system

20 March 2017

1 reference

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beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee

20 March 2017

1 reference

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c-Myc-regulated microRNAs modulate E2F1 expression

20 March 2017

1 reference

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Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells

20 March 2017

1 reference

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Medulloblastoma: developmental mechanisms out of control

20 March 2017

1 reference

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Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling

20 March 2017

1 reference

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N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

20 March 2017

1 reference

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Neuroimaging studies of word reading

20 March 2017

1 reference

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The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation

20 March 2017

1 reference

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Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

20 March 2017

1 reference

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Altered neural cell fates and medulloblastoma in mouse patched mutants

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

A translational profiling approach for the molecular characterization of CNS cell types

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Medulloblastoma comprises four distinct molecular variants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Pleiotropic role for MYCN in medulloblastoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Role of high-dose chemotherapy for recurrent medulloblastoma and other CNS primitive neuroectodermal tumors

29 September 2017

1 reference

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Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.

29 September 2017

1 reference

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Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

29 September 2017

1 reference

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Cerebellar granule cells: insights into proliferation, differentiation, and role in medulloblastoma pathogenesis

29 September 2017

1 reference

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Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells

29 September 2017

1 reference

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Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

The origins of medulloblastoma subtypes

29 September 2017

1 reference

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Multi-institution prospective trial of reduced-dose craniospinal irradiation (23.4 Gy) followed by conformal posterior fossa (36 Gy) and primary site irradiation (55.8 Gy) and dose-intensive chemotherapy for average-risk medulloblastoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Differentiation of ES cells into cerebellar neurons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Hedgehog checkpoints in medulloblastoma: the chromosome 17p deletion paradigm.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Time and tide in cerebellar memory formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Notch1 and notch2 have opposite effects on embryonal brain tumor growth

29 September 2017

1 reference

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Cerebellum-dependent learning: the role of multiple plasticity mechanisms

29 September 2017

1 reference

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The rhombic lip and early cerebellar development

29 September 2017

1 reference

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Otx2, Gbx2 and Fgf8 interact to position and maintain a mid-hindbrain organizer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Quantitative analysis of cell proliferation and differentiation in the cortex of the postnatal mouse cerebellum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Unipolar brush cell: a potential feedforward excitatory interneuron of the cerebellum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum

29 September 2017

1 reference

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Neuropsychological consequences of cerebellar tumour resection in children: cerebellar cognitive affective syndrome in a paediatric population

29 September 2017

1 reference

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Autoregulation and multiple enhancers control Math1 expression in the developing nervous system

29 September 2017

1 reference

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Engrailed, Wnt and Pax genes regulate midbrain--hindbrain development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Learning and Memory in the Vestibulo-Ocular Reflex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Mechanisms of Neural Patterning and Specification in the Development Cerebellum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

2 June 2018

1 reference

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Application of a translational profiling approach for the comparative analysis of CNS cell types

2 June 2018

1 reference

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Antagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lip.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Gli1 is important for medulloblastoma formation in Ptc1+/- mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Using Flp-recombinase to characterize expansion of Wnt1-expressing neural progenitors in the mouse

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Math1 is essential for genesis of cerebellar granule neurons

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Differential expression of Notch family members in astrocytomas and medulloblastomas

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Loss of suppressor-of-fused function promotes tumorigenesis.

27 November 2018

1 reference

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Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Molecular markers of neuronal progenitors in the embryonic cerebellar anlage.

27 November 2018

1 reference

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Expression of Notch and Wnt pathway components and activation of Notch signaling in medulloblastomas from heterozygous patched mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Cognition, emotion and the cerebellum

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Radial glia serve as neuronal progenitors in all regions of the central nervous system

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

A molecular fingerprint for medulloblastoma.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Extending the cerebellar Lugaro cell class

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

The role of the rhombic lip in avian cerebellum development

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Failure of cerebellar patients to time finger opening precisely causes ball high-low inaccuracy in overarm throws

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Cerebellar contributions to cognition.

27 November 2018

1 reference

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Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

H3-thymidine autoradiographic studies on the cell proliferation and differentiation in the external and the internal granular layers of the mouse cerebellum

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051031

Incomplete penetrance of the predisposition to medulloblastoma associated with germ-line SUFU mutations

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21315459

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TINS.2011.01.002

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21315459

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21315459%20AND%20SRC:MED&resulttype=core&format=json