THE TAMIL NADU DR. M.G.R.

MEDICAL UNIVERSITY

[BPHARM 0321] MARCH 2021 Sub. Code: 2061

(SEPTEMBER 2020 EXAM SESSION)
B. PHARMACY DEGREE EXAMINATION
PCI Regulation SEMESTER  VI
PAPER II – PHARMACOLOGY III
Q.P. Code : 562061
Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Classification of anti-tubercular drugs. Describe briefly the mechanism of action,

adverse drug reaction and therapeutic uses of Isoniazid.
2. Classify anti-emetic drugs. Write the mechanism of action, adverse effects and uses
of prokinetic agents.
3. Classify the Immuno suppressants. Write in detail about the mechanism of action,
adverse effects and therapeutic uses of Cyclosporine.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Types of monoclonal antibodies and its application.

2. Mechanism of action and uses of beta lactamase inhibitors
3. Write a note on proton pump inhibitors.
4. Enumerate newer macrolide antibiotics and its mechanism of action and uses.
5. Give brief account on anti- Helicobacter pylori regimen.
6. Write a note on drugs used in prophylaxis of malaria.
7. What is cotrimoxazole? Give its therapeutic uses and mechanism of action.
8. Write a note on natural anti cancer drugs.
9. Write a note on Dimercaprol.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Spectrum of action and uses of monobactam.

2. Why antacid should not be given with sucralfate in the treatment of peptic ulcer
disease.
3. How does vancomycin produce “Red man syndrome”.
4. Symptoms and treatment of Mercury poisoning.
5. Circadian rhythm and its influence in Chrono therapeutics.
6. Give examples for osmatic purgatives and their uses.
7. Name two retroviral protease inhibitors.
8. Mention the drugs for urinary tract infection.
9. Adverse effect of Chloramphenicol.
10. Example of drugs for treating candidiasis.

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 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BPHARM 0921] SEPTEMBER 2021 Sub. Code: 2061

(SEPTEMBER 2020 EXAM SESSION)

B.PHARM. DEGREE EXAMINATION

PCI Regulation 2017 – SEMESTER VI
PAPER II – PHARMACOLOGY III
Q.P. Code : 562061
Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Classify anti-asthmatic drugs. Write the mechanism of action, pharmacological

action and therapeutic uses of Theophylline.
2. Define anti-microbial agents, classify Penicillins. Explain the mechanism of action,
adverse drug reaction and uses of Penicillin G.
3. Classify the anti-malarial drugs. Write in detail about the mechanism of action,
adverse effects and therapeutic uses of Chloroquine.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Write a note on Expectorants

2. Mechanism of action and uses of proton pump inhibitors
3. Write a note on anti-diarrhoeal drugs
4. Classify aminoglycoside antibiotics. Write adverse effects and therapeutic uses of
Gentamicin.
5. Mechanism of action and therapeutic uses of fluoroquinolones.
6. Explain treatment regimens in Tuberculosis.
7. Mechanism of action of antimetabolites.
8. Write a note on Immuno suppressants.
9. General principles in the treatment of poisoning

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Give examples of saline purgatives

2. Define carminatives and its uses.
3. Comment the usefulness of corticosteroid in autoimmune disorders.
4. Define the term carcinogenicity
5. Name two appetite stimulants
6. Give examples of antitussive agents
7. Enumerate two anthelmintic drugs.
8. Mention the drugs for herpes zoster infection.
9. What should be avoided when taking Tetracycline?
10. Microtubule damaging anti-cancer drugs
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BPHARM 0122] JANUARY 2022 Sub. Code: 2061

(MARCH 2021 EXAM SESSION)

B.PHARMACY DEGREE COURSE (SEMESTER EXAMINATIONS)

PCI Regulation 2017 – SEMESTER VI
PAPER II – PHARMACOLOGY III
Q.P. Code : 562061
Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Classify anti-ulcer drugs. Write the pharmacological action, mechanism of action

and uses of H2 receptor antagonist.
2. Classify Cephalosporin. Write the mechanism of action, adverse effects and uses of
third generation cephalosporin drugs.
3. Discuss in detail about the classification of anti-cancer drugs. Write the mechanism
of action, adverse drug reaction and uses of alkylating agents.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Give brief account on Griseofulvin.

2. Mechanism of action, drug interaction and uses of streptomycin.
3. Classify the drugs used in the therapy of constipation and add a note on mechanism
of action.
4. Classify anti-retro viral drugs. Write adverse effects and therapeutic uses of
zidovudine.
5. Write a note on Diloxanide furoate.
6. Write short notes on Artemisinin derivatives.
7. Mechanism of action and uses of sulphamethaxazole.
8. Classify heavy metals poisoning and its antagonist.
9. Define Biological clock and its significance.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Name two Mast cell stabilizers.

2. Mention the non-systemic antacids which neutralize the gastric acid secretion.
3. Define Teratogenicity and give two examples of drug causing teratogenicity.
4. Example for drugs used in the management of emesis.
5. Why is clofazimine used as a component of multidrug therapy in leprosy?
6. Name two antifungal antibiotics.
7. Therapeutic uses of Metronidazole.
8. Mention any two drugs for urinary tract infection.
9. Rationale of using Levamisole as immunostimulant.
10. Common adverse drug reaction associated with the use of anticancer drugs.
*******
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BPHARM 0522] MAY 2022 Sub. Code: 2061

(SEPTEMBER 2021 EXAM SESSION)
B. PHARMACY DEGREE EXAMINATION
PCI Regulation SEMESTER - VI
PAPER II – PHARMACOLOGY III
Q.P. Code : 562061
Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Classify anti-asthmatic drugs. Write the pharmacological actions, ADR and therapeutic
uses of selective Beta2 (ß2)-agonists.
2. Classify Anti-ulcer agents. Write the pharmacological actions, adverse effects and
therapeutic uses of proton pump inhibitors.
3. Classify Anti-neoplastic agents. Discuss the Mechanism of action, adverse drug reaction,
therapeutics uses of alkylating agents.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Mast cell stabilizers.

2. Define and classify Laxatives. Mention its uses. Discuss the mechanism of Bulk and
Stimulant Purgatives.
3. 5HT3 antagonists.
4. Anti-leprotic drugs.
5. Cyclosporine
6. Signs and treatment of Arsenic poisoning.
7. Cotrimoxazole
8. Write short notes on protease inhibitors.
9. Write a note on chemotherapy of Sexually Transmitted Diseases
III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. What is status asthmaticus? Site the drug of choice?

2. Name two mucolytics.
3. Define prokinetics with examples.
4. Name two appetite stimulants.
5. Examples for Beta lactamase inhibitor.
6. List out the toxicities of Aminoglycoside antibiotics.
7. Comment the usefulness of Sulfasalazine in inflammatory bowel disease.
8. Side effects of Metronidazole.
9. Chronotherapy.
10. What is the antidote for lead poisoning?

*******
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[BPHARM 1022] OCTOBER 2022 Sub. Code: 2061

(MARCH 2022 EXAM SESSION)

B.PHARMACY DEGREE COURSE (SEMESTER EXAMINATIONS)

PCI Regulation 2017 – SEMESTER VI
PAPER II – PHARMACOLOGY III
Q.P. Code : 562061
Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Classify Anti-ulcer agents. Describe the pharmacology of proton pump

inhibitors and H2 receptor blockers.
2. Classify Anti-cancer agents. Write the mechanism of Alkylating Agents.
3. a) Classify antiasthmatic drugs.
b) Mechanism of action of fluoroquinolones.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Bronchodilators.
2. Biological clock.
3. Discuss the symptoms and treatment of lead Poisoning.
4. Enumerate drugs used in urinary tract infection.
5. Mebendazole.
6. Explain briefly the general principles of Acute and chronic toxicity.
7. Discuss the mechanism of Nucleoside Reverse Transcriptase Inhibitors.
8. Classify Antidiarrhoeal Agents.
9. Classify Antiviral Agents.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. What are Immuno suppressants? Name two immuno suppressive drugs.

2. What are the Adverse effects of chloroquine?
3. Define the term Teratogenecity with example.
4. Name two drugs used in AIDS.
5. What are monoclonal antibodies?
6. Mast Cell Stabilizers.
7. What are appetite stimulants give examples.
8. Write the uses and adverse effects of macrolide antibiotics.
9. Write the antileprotic drugs.
10. Anti fungal antibiotics.
*******
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[B.PHARM 0323] MARCH 2023 Sub. Code: 2061

(SEPTEMBER 2022 EXAM SESSION)

B.PHARMACY DEGREE COURSE (SEMESTER EXAMINATIONS)

PCI Regulation 2017 – SEMESTER VI
PAPER II – PHARMACOLOGY III

Q.P. Code: 562061

Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Classify Anti-tubercular agents. Add a note on mechanism of action,

pharmacolgical actions and adverse effects of Anti-tubercular drugs.
2. Classify cephalosporins. Write the mechanism of action, adverse effects and
uses of cephalosporins.
3. a) Classify antitussive drugs.
b) Mechanism of action of cotrimoxazole.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Write the importance of chronotherapy with example.

2. Discuss the symptoms and treatment of arsenic poisoning.
3. Enumerate drugs used in sexually transmitted diseases.
4. Explain briefly about immnosuppresants.
5. Discuss the mechanism of Nucleoside Reverse Transcriptase Inhibitors.
6. Classify Anthelmintic Agents.
7. Nasal decongestants.
8. Bronchodilators.
9. Antimetabolites in cancer.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. What are Anti emetics?

2. Lepra reaction.
3. Define the term genotoxicity.
4. Name two drugs used in anti amoebic drugs.
5. What are antifungal antibiotics?
6. Mast cell stabilizers.
7. What are digestants give examples.
8. What are proton pump inhibitors?
9. Biological clock.
10. What are the adverse effects of amino glycoside antibiotics?
*******
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[B.PHARM 0823] AUGUST 2023 Sub. Code: 2061

(MARCH 2023 EXAM SESSION)

B.PHARMACY DEGREE COURSE (SEMESTER EXAMINATIONS)

PCI Regulation 2017 – SEMESTER VI
PAPER II – PHARMACOLOGY III

Q.P. Code: 562061

Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Mechanism of action, Spectrum of activity, adverse effects and uses of

Fluoroquinolones.
2. Classify anti-emetics drugs. Describe the mechanism of action, therapeutic uses
and adverse effects of D2 receptor antagonists.
3. Classify Immunosuppressants. Describe the mechanism of action, therapeutic uses
and adverse effects of cyclosporine.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Drugs used in the Treatment of Urinary Tract Infections.

2. Zidovudine.
3. Define asthma and write the pharmacological action of and therapeutic uses of
theophyline.
4. Antacids.
5. Bacterial resistance.
6. What is the role of Vinca alkaloids in treatment of cancer?
7. Aminoglycoside Antibiotics.
8. Signs and treatment of morphine poisoning.
9. Proton Pump Inhibitors.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Drugs used to treat Zollinger ellison syndrome.

2. Define anorexiants with examples.
3. Name two drugs that suppress dry cough.
4. Define acute and subacute toxicity studies.
5. Jet-lag.
6. Give example for Leukotriene Antagonist and write its uses.
7. Biosimilars.
8. Therapeutic Uses of Macrolide antibiotics.
9. Adverse effects of Tetracycline.
10. Mention the uses of Terbinafine.
*******
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[B.PHARM 1223] DECEMBER 2023 Sub. Code: 2061

(SEPTEMBER 2023 EXAM SESSION)

B.PHARMACY DEGREE COURSE (SEMESTER EXAMINATIONS)

PCI Regulation 2017 – SEMESTER VI
PAPER II – PHARMACOLOGY III

Q.P. Code: 562061

Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Classify Anti-tubercular drugs. Explain the mechanism of action, therapeutic uses,

drugs interactions and adverse effect of Isoniazid and Rifampicin.
2. a) Write elaborately on the general principals in the treatment of poisoning.
b) Write notes on Heavy Metal Poisoning.
3. Classify beta-lactam antibiotics and describe mechanism of action, therapeutic uses
and adverse effect of any two beta-lactam antibiotics.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. What is cough? Explain the drugs used in the treatment of cough.

2. H2 receptor antagonists.
3. Fluoroquinolones.
4. Classify Antiviral Agents. Discuss the mechanism of Nucloside Reverse Transcriptase
Inhibitors.
5. Anti-metabolites.
6. Write notes on Immunostimulants.
7. Define Chronopharmacology. Discuss the applications of Chronotherapeutics in the
treatment of diseases.
8. Write the symptoms and treatment of Organophosphorus poisoning.
9. Anti-diarrhoeal drugs.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Two examples of Nasal decongestants.

2. Write two examples of Antiulcer drugs.
3. What are respiratory stimulants? Give two examples.
4. Anti herpes drugs.
5. Adverse effect of chloroquine.
6. Name two antifungal antibiotics.
7. What is British Anti-Lewisite (BAL)? Write its therapeutic application.
8. Define the term lepra reaction.
9. Define the term carcinogenicity and mutagenicity.
10. Circadian rhythm.
*******
 THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY

[B.PHARM 0524] MAY 2024 Sub. Code: 2061

B.PHARMACY DEGREE COURSE (SEMESTER EXAMINATIONS)

PCI Regulation 2017 – SEMESTER VI
PAPER II – PHARMACOLOGY III

Q.P. Code: 562061

Time: Three hours Maximum: 75 Marks

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Classify Anti-malarial agents. Add a note on mechanism of action, pharmacological

actions and adverse effects of any one drug.
2. Classify pencillins. Write the mechanism of action, adverse effects and uses of
pencillins.
3. a) Classify antacids with examples.
b) Classify antidiarrhoeal drugs with example.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Mechanism of action of fluoroquinolones.

2. What are the general treatments of poisoning?
3. Classify antifungal drugs.
4. Explain briefly about immnosuppresants.
5. Discuss the mechanism of any one antiviral drug.
6. Classify Antiamoebic Agents.
7. What are biosimillars? Give example.
8. Bronchodilators.
9. Classify anti-cancer drugs.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. What are mucolytics?

2. Define the term mutagenicity.
3. Name two anthelmintic drugs.
4. What are the uses of sulphonamides?
5. Mast cell stabilizers.
6. What are digestants give examples.
7. Write the clinical uses of aminoglycoside antibiotics.
8. What are the drugs effective against H.Pylori?
9. What are Prokinetics? Give example.
10. Biological clock.
*******