CANDIDATE EXAMINATION NUMBER……………………………………………………

MINISTRY OF HEALTH, COMMUNITY DEVELOPMENT, GENDER, ELDERLY AND

CHILDREN

KIGAMBONI CITY COLLEGE OF HEALTH AND ALLIED SCIENCES

BASIC TECHNICIAN CERTIFICATE IN PHARMACEUTICAL SCIENCES

CONTINUOUS ASSESSMENT TEST – II

SEMESTER II - NTA LEVEL - 4

PST04211: BASCI PHARMACOLOGY

TIME: 09:00 – 11:00 AM DATE:

(THEORY PAPER)

INSTRUCTIONS:

1. This paper consists of FIVE sections. A, B, C, D and E. Attempt ALL questions in all sections.
2. Follow instructions given in each section
3. Read each question carefully before you attempt it
4. Write your Examination number on every page you use
5. ALL ANSWERS TO BE WRITTEN IN THE ANSWER BOOKLET PROVIDED
6. ALL UNAUTHORIZED MATERIALS ARE NOT ALLOWED e.g. Mobile phones or other
electronic devices
7. This examination consists of SIX (8) printed pages

FOR OFFICIAL USE ONLY

SECTION No OF MARKS MARKS EXAMINER

QUESTION (s) ALLOCATED GAINED
SECTION A: MULTIPLE CHOICE QUESTIONS 10 10
SECTION B: MULTIPLE TRUE & FALSE QUESTIONS 8 20
SECTION C: MATCHING ITEMS QUESTIONS 2 10
SECTION D: SHORT ANSWER QUESTIONS 8 40
SECTION E: GUIDED ESSAY ANSWER QUESTIONS 2 20
TOTAL 100 MARKS

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SECTION A: MULTIPLE CHOICE QUESTIONS (10 marks)

 This section consists of 10 questions
 For each question on this section choose the most correct answer among the
options given and write the letter of the answer on the booklet provided.
 Each question carries 1mark
1. The first line treatment for uncomplicated malaria in non-pregnant
adults and children in Tanzania is
A. Quinine
B. Sulphadoxine and Pyrimethamine (SP)
C. Artemether and Lumefantrine
D. Mefloquine
E. Artesunate injection

2. Anusol suppository is used in the management of ……….

A. Aneurysm
B. Appendicitis
C. Warts
D. Psoriasis
E. Haemorrhoids

3. Metallic taste is a common side effect of which drug?

A. Amoxicillin
B. Mebendazole
C. Vitamin A
D. Ciprofloxacin
E. Metronidazole

4. Acyclovir is an antiviral drug used in the management of ………

infection.
A. HIV/AIDS
B. Hepatitis
C. Infulenza
D. Herpes simplex virus
E. Chickenpox

5. Drowsiness is a common side effect of which class of drugs?

A. Antihelmintics
B. Antihistamines
C. Vaccines

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D. Antispasmodics
E. Anti-anaemic
6. Antiviral drugs are used in the treatment of ……….. infections
A. Bacterial
B. Fungal
C. Protozoal
D. Helminthic
E. Viral

7. Hyoscine butylbromide is used in managent of……….

A. Amenorrhea
B. Alopecia
C. Anorexia
D. dysmenorrhea
E. Amenorrhea

8. Ferrous sulphate is used to manage

A. Aplastic anemia
B. Sickle cell anemia
C. Megaloblastic anemia
D. Pernicious anemia
E. Iron-deficiency anemia

9. Pseudoephedrine is used in the management of …………

A. Conjunctivitis
B. Nasal congestion
C. Asthma
D. Cough
E. Hypertension

10. Oxytocin belongs to a class of drugs called…..

A. Oxytocics
B. Vaccines
C. Muscle relaxants
D. Antineoplastic agents
E. Lipid lowering agents

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 CANDIDATE EXAMINATION NUMBER……………………………………………………

SECTION B: MULTIPLE TRUE/FALSE (20 marks)

 This section consists of eight (8) questions each with five (5) alternatives

 Write the word TRUE for a correct alternative and the word FALSE for a wrong
alternative in the answer booklet provided.

 Each question carries 2.5 marks

1. Amoxycillin is
A. A cephalosporin antibiotic- FALSE
B. Contraindicated in patients with penicillin hypersensitivity- TRUE
C. Contraindicated in children below 12 years- FALSE
D. A penicillin antibiotic- TRUE
E. Active against many Gram positive and some Gram negative bacteria- TRUE

2. Rgarding antiacids, they

A. Should be taken at the same time with tetracyclines- FALSE
B. Should be taken at the same time with fluoroquinolones- FALSE
C. Should be taken at the same time with iron preparations- FALSE
D. Are basic compounds-TRUE
E. Are acidic compounds-FALSE

3. Albendazole is effective treatment for the following parasites:

A. Hookworms- TRUE
B. Roundworms- TRUE
C. Tapeworms-TRUE
D. Strongyloides- TRUE
E. Cutaneous lava migrans- FALSE

4. Topical anti-inflammatory agents are used in the management various

conditions including:
A. Inflammatory conditions of the skin- TRUE
B. Contact dermatitis-TRUE
C. Insects sting-TRUE
D. Eczema-TRUE
E. Psoriasis-TRUE
5. Adverse and side effects of ORS include
A. Headache- FALSE
B. Dizziness- FALSE
C. Constipation- TRUE
D. Drowsiness- FALSE

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E. Sedation- FALSE
6. The adverse and side effects of corticosteroids include
A. Skin atrophy (thinning of skin)- TRUE
B. Erythema- TRUE
C. Steroid acne -TRUE
D. Hypopigmentation -TRUE
E. Gastric ulceration-TRUE

7. Regarding hydrocortisone, it is used in management of various conditions

including:
A. adrenocortical insufficiency-TRUE
B. anaphylactic shock and angioedema- TRUE
C. asthma-TRUE
D. severe inflammatory bowel disease- FALSE
E. haemorrhoids and rheumatic disease- FALSE

8. Chronic use of aspirin is associated with side and adverse effects including:
A. Gastric ulcers- TRUE
B. Psychosis- FALSE
C. Increased bleeding time- TRUE
D. Anemia- FALSE
E. Thrombosis- FALSE

SECTION C: MATCHING ITEMS (10 marks)

 This section contains two questions each with five items
 Match the items from column B to the corresponding statements in column A

Part I. Match the drug class from list B to the corresponding drug in list A
LIST A LIST B
1. Flucloxacillin- C A. Tetracycline
2. Ciprofloxacin- G B. Antihistamine
3. Erythromycin- D C. Penicillin
4. Doxycycline- A D. Macrolide
5. Gentamycin- F E. Corticosteroid
F. Aminoglycoside
G. Fluoroquinolone

Part II. Match the indication from list B to the corresponding drug in list A
LIST A LIST B
1. Salbutamol- E A. Inflammation
2. Chlorpheniramine- G B. Pain and fever
3. Paracetamol- B C. Eclampsia
4. Diazepam (Valium)- D D. Convulsion
5. Magnesium trisilicate- E E. Asthma

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F. Anemia
G. Allergy
SECTION D
 This section consists of eight (8) short answer questions. Each question carries
five (5) marks.
 Attempt all questions.

1. Mention five (5) examples of adrenal hormone drugs

i. Bethamethasone
ii. Dexamethasone
iii. Clobetasol
iv. Hydrocortisone
v. Predinisolone
2. What are the drug of choice for treatment of pulmonary edema, erectile
dysfunction and edema of lower limbs?
i. Pulmonary edema- FRUSOMIDE
ii. Erectile dysfunction- SILDENAFIL/ TADALAFIL
iii. Edema of lower limbs- FRUSEMIDE/ HYDROCHLOROTHIAZIDE
3. List three (3) classes of diuretic agents giving example of a drug under each class
i. Thiazides :- hydrochlorothiazide
ii. Loop diuretics:- frusomide
iii. Potassium spairing diuretics: spironolactone
4. State the indication of thyroid hormones drugs
Indicated for treatment of THYROTOXICOSIS
Four side effects associating with thyroid hormone drugs
i. Malaise
ii. Dizness
iii. Headache
iv. Gastro intestinal ulcerations
5. Mention five (5) antifungal drugs
i. Ketoconazole
ii. Fluconazole
iii. Clotrimazole
iv. Itraconazole
v. Terbinafine
vi. Griseofluvin
6. Mention five (5) classes of anti-hypertensive agents giving example under each
class
i. Beta blockers example atenolol
ii. Calcium channel blockers example verapamil
iii. Angiotensin II converting enzymes inhibitors example captopril

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iv. Angiotensin receptor blockers example ibesartan

v. Diuretics example frusemide
7. Describe five (5) classes of hypolipidermic (lipid lowering) agents, giving one
example of a drug under each class
i. Statins example atrovastatins
ii. Vitamin B3 example Niacin
iii. Fibrates example fenofibrates
iv. Bile acid sequestrants example cholestipol
v. Azitidiones example ezitimide
8. List five (5) important drug-drug interaction of essential medicines
i. Aspirin with warfarin
ii. Anti acids with tetracycline
iii. Frusemide with verapamil
iv. Quinine with digoxin
v. Metronidazole with alcohol
vi. Nitroglycerine with propranolol.

SECTION E: ESSAY QUESTIONS (20 marks)

This section consists of two (2) essay questions. Attempt ALL questions. Each question
carries 10 marks

1. Describe one indication, side effects, adverse effects and contraindications for
each of the following anti-diabetic drugs.
Insulin injection
Indicated for type I diabetic, side effect-local irritation at the site of injection,
adverse effect anaphylaxis reactions, and contraindication hypersensitivity.
Metiformin
Indicated for type II diabetic, side effect metallic taste, adverse effect
hypoglycemic, contraindication to pregnancy women
Glibenclamide
Indication type II diabetic, side effects allergic reaction, adverse effects neuron
toxicity, contraindicated to lactating women and pregnancy women’s.
Chloropropamide
Indication type II diabetic, side effects nausea and vomiting, adverse effects
dizziness and confusion contraindication renal insufficiency patients

2. With the aid of examples describe six (6) classes of essential medicines used for
management of different cardiovascular disorders
Beta blockers-indicated for hypertension example atenolol
Cardiac glycosides- indicated for cardiac failure example digoxin

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Angiotensin converting enzymes inhibitors- indicated for heart failure example

captopril
Diuretics indicated for hypertension example frusemide
Angiotensin receptor blockers indicated for heart failure and hypertension
example losartan
Calcium channel blockers indicated for cardiac arrythmiasis example verapamil

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