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Neuropathic pain is caused by disorders of, or damage to, the nervous system. The affected nerves can induce the sensation of pain in the brain. Neuropathic pain is often associated with the sensation of burning, coldness, "pins and needles", numbness or itching.
Spinal cord stimulation is seen as a last-resort therapy for the treatment of chronic pain. Controversies surrounding the treatment might be addressed through collaborative efforts to conduct innovative clinical trials and reach consensus on treatment guidelines.
A new report shows that chronic pain leads to accumulation of pathological forms of tau protein in the hippocampus, resulting in neuronal atrophy and cognitive impairment.