Trifluoperazine
1 Follower
Recent papers in Trifluoperazine
Previous studies have shown that bleomycin-induced pulmonary fibrosis is accompanied by elevated levels of calcium and calmodulin, which are important in the regulation of many biologic processes. The authors have further extended these... more
TLR3 is one of the major innate immune sensors of dsRNA. The signal transduction pathway activated by TLR3, upon binding to dsRNA, leads to the activation of two major transcription factors: NF-kappaB and IFN regulatory factor (IRF) 3. In... more
The making and sealing of a tight junction (TJ) requires cell-cell contacts and Ca2−, and can be gauged through the development of transepithelial electrical resistance (TER) and the accumulation of ZO-1 peptide at the cell borders. We... more
Human ejaculated spermatozoa take up zinc in a time- and concentration-dependent manner. The kinetics of 65Zn2+ uptake is suggestive of an at least partly carrier-mediated transport. The lack of effect of the respiratory chain inhibitor... more
Bee vemon (BV) is used in folk medicine to treat arthritis. It has antiinflammatory effects in animal models of rheumatic disease. We have studied the effects of BV on human neutrophil production of superoxide (O 2-) and hydrogen... more
Trifluoperazine hydrochloride (TFPH), 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl )-10H-phenothiazine hydrochloride (Fig. 1) is a prominent compound in a large group of phenothiazine derivatives. Trifluoperazine (TFP) has... more