Pharmacotherapy
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Recent papers in Pharmacotherapy
The aim of the present study was to formulate and evaluate Metformin HCl microspheres to produce a drug delivery system with better pharmaceutical and therapeutic properties. Metformin HCl microspheres were prepared by using ethyl... more
Résumé/Abstract In 2000, the Society of Critical Care Medicine (SCCM) and the American College of Clinical Pharmacy (ACCP) published a position paper that defined critical care pharmacy services as fundamental, desirable, and optimal. A... more
Peptic ulcer is a disorder of the upper gastrointestinal tract that is caused by gastric acid. There are various chemical agents available for the treatment of peptic ulcers, but claim serious side effects. Herbal drugs are preferred over... more
Coronary artery bypass grafting (CABG) is an established revascularization procedure for the treatment of advanced atherothrombotic coronary artery disease.1 The National Center for Health Statistics estimated that 427,000 procedures were... more
La enfermedad de Parkinson fue descrita por primera vez en el año 1817 por el médico inglés James Parkinson, en su “Ensayo sobre la parálisis agitante”, donde sistematizaba las descripciones clínicas de una serie de pacientes, que se... more
A novel is ligand namely 5,5'-(6-(4-methoxyphenoxy)-1,3,5-triazine-2,4-diyl)bis (azanediyl)diquinolin-8-ol (PBDQ-6) has been prepared and characterized. This ligand was characterized by IR, 1H-NMR, and elemental analysis. Coordination... more
Systematic management models such as anticoagulation clinics have emerged in order to optimize warfarin effectiveness and to minimize related complications. Most of these models are structured so that patients come to a clinic for... more
With the continuing evolution of pharmacy as a clinical profession, the need to prepare well-trained clinicians beyond the knowledge gained from a doctor of pharmacy degree program is magnified. Such training is afforded by pharmacy... more
To assess the effect of health literacy on drug adherence in the context of a pharmacist-based intervention for patients with heart failure. Post hoc analysis of a randomized controlled trial. Inner-city ambulatory care practice... more
A simple, fast and accurate method has been developed for the estimation of benzene content in Lovastatin by Gas Chromatography. The analysis was carried out on Perkin Elmer Clarus 600 GC-HS Chromatograph. The column... more
Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3,4-methylenedioxymethamphetamineassisted psychotherapy: a prospective longterm follow-up study
A 55-year-old Caucasian man was receiving warfarin therapy after undergoing aortic valve replacement. His international normalized ratio (INR) was stabilized with warfarin 95 mg/week for 5 weeks. Commencement of a low-carbohydrate,... more
Carvedilol is an antihypertensive drug use for management of Hypertension. It has the half-life of 6 hr and oral bioavailability of 25% due to first pass metabolism. The total daily dose of Carvedilol is 25 mg, hence it required frequent... more
A new simple, accurate, precise and reproducible Ion chromatography method has been developed for the estimation of Methane sulfonic acid in Busulfan injectable dosage. The method which is developed is also validated in complete... more
The purpose of this study was to evaluate the possibility of taste masking of Levocetirizine dihydrochloride (L-CTZ) by means of inclusion complexation and ion exchange resin. Initially an attempt was given to mask the bitter taste of the... more
The objective of present study was to develop pharmaceutically elegant and stable enteric coated tablet formulation for highly unstable drug in acidic environment using pH dependent polymers. Omeprazole is a specific and non-competitive... more
Impurity profiling is the process of acquiring and evaluating data that establishes biological safety of an individual impurity. Impurity is considered as any other organic material, besides the drug substance, or ingredients, arise out... more
A straightforward, efficient and more sustainable solvent-free method has been developed for the synthesis of benzimidazole derivatives to achieve yields that were comparable to or better than, those in conventional media. It is... more
An accurate, precise, simple and economical High Performance Liquid Chromatographic method for the Estimation of Bortezomib in its lyophilized dosage form has been developed. The method developed is Reverse Phase High Performance Liquid... more
Quality by Design (QbD) refers to a holistic approach towards drug development. The purpose of research was to implement quality by design to study prospective process validation of 4 mg Salbutamol Sulphate Tablets with risk-based... more
A lo largo del capítulo recordaremos los aspectos más relevantes de la farmacología de los fármacos antiparasitarios, haciendo especial énfasis en la localización de sus efectos en el ciclo biológico del parásito, así como en el resto de... more