Brain Tumors
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Recent papers in Brain Tumors
Machine learning (ML) and computer vision systems revolutionized the world, especially deep learning (DL) for convolutional neural networks, which has proven breakthroughs in brain tumor (BT) diagnosis. This study investigates a... more
Brain tumor is an abnormal growth of mass of cells in (or) around the brain. Brain tumors can be malignant (cancerous) or being non-cancerous. It is the most common malignant primary intracranial tumors of central nervous system. Brain... more
Over 80% of diffuse intrinsic pontine gliomas (DIPGs) harbor a point mutation in histone H3.3 where lysine 27 is substituted with methionine (H3.3K27M); however, how the mutation affects kinetics and function of PcG proteins remains... more
─ Convection-enhanced delivery as a means to deliver therapeutic drugs directly to the brain has shown limited clinical efficacy, primarily attributed to the phenomena of backflow, in which the infused fluid flows preferentially along the... more
The use of medical imaging technology aids clinicians in recognizing and assessing patient problems, as well as improving treatment procedures. However, while conducting complex procedures such as the excision of brain tumors, the... more
Magnetic resonance imaging (MRI) is the current gold standard for the diagnosis of brain tumors. However, despite the development of MRI techniques, the differential diagnosis of central nervous system (CNS) primary pathologies, such as... more
Purpose. We studied the prognostic significance of Magnetic Resonance Spectroscopy (MRS) in operated high grade gliomas.Materials and Methods. Twelve patients were treated with radiotherapy and Temozolomide. The MRS data were taken four... more
In most cases, macroautophagy/autophagy serves to alleviate cellular stress and acts in a pro-survival manner. However, the effects of autophagy are highly contextual, and autophagic cell death (ACD) is emerging as an alternative paradigm... more
Nowadays, clinical practice in Gamma Knife treatments is generally based on MRI anatomical information alone. However, the joint use of MRI and PET images can be useful for considering both anatomical and metabolic information about the... more
Many thousands of published papers, a lot of communications and daily practice show the outstanding role of proton spectroscopy (1H MRS) in neurooncology. Paradoxically, in several clinical centres (neurosurgery ones) we can observe the... more
The current challenge in automatic brain tumor classification based on MRS is the improvement of the robustness of the classification models that explicitly account for the probable breach of the independent and identically distributed... more
Glioblastoma (GBM) is a highly aggressive brain tumor and almost all patients die because of relapses. GBM-derived cells undergo cell death without nuclear fragmentation upon treatment with different apoptotic agents. Nuclear dismantling... more
E-Mail Contact- OUDRHIRI Mohammed Yassaad: yassaad1 (at) msn (dot) com
Significance Vessel cooption is a strategy that many tumors employ to progress without creating new blood vessels but by exploiting preexisting vessels of the host tissue. In addition to promoting tumor growth, cooption is also associated... more
RNA modifications are emerging as critical regulators in cancer biology, thanks to their ability to influence gene expression and the predominant protein isoforms expressed during cell proliferation, migration, and other pro-oncogenic... more
Accurate discrimination between high grade gliomas (HGG)
and metastatic brain tumor (MET) using noninvasive imaging
is essential for selecting appropriate surgical and radiotherapy treatments and for determining the treatment response.
and metastatic brain tumor (MET) using noninvasive imaging
is essential for selecting appropriate surgical and radiotherapy treatments and for determining the treatment response.
To assess the potential of thymidine for imaging brain tumors, 20 patients with untreated (n = 14) and recurrent (n = 6) supratentorial intracranial tumors were studied with PET by using 2-[11C]thymidine (Tdr), and the results were... more