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Background and AimsCervical radiculopathy (CR) is a group of signs and symptoms caused by cervical root dysfunction. Patients with this condition may also have carpal tunnel syndrome (CTS), which is caused by compression of the median... more
Background and AimsCervical radiculopathy (CR) is a group of signs and symptoms caused by cervical root dysfunction. Patients with this condition may also have carpal tunnel syndrome (CTS), which is caused by compression of the median nerve in the carpal tunnel. This coexistent condition is referred to as double crush syndrome (DCS) which is explained by proximal disruption in axoplasmic flow that may result in nerve dysfunction. Yet, the accuracy of this hypothesis remains controversial.Materials and MethodsPatients with confirmed CR according to electromyography were included in this retrospective study. However, we omitted patients with overt diabetic neuropathy, prior spinal or hand surgery and/or fractures, and rheumatoid arthritis. Patients underwent electrodiagnostic studies, and the results were used to determine CTS severity. We used Pearson's χ2 test to assess the correlation between the severity of CTS and CR. Descriptive analysis was used to report patient characteri...
Background: Long-term complications of stroke, persisting for more than 6 months after the initial event, substantially reduce the quality of life (QoL) in a significant percentage of stroke survivors. In this paper, we studied the... more
Background: Long-term complications of stroke, persisting for more than 6 months after the initial event, substantially reduce the quality of life (QoL) in a significant percentage of stroke survivors. In this paper, we studied the prevalence of long-term urinary incontinence (UI) in post-stroke patients. In addition, we attempted to identify patient characteristics which were associated with higher UI prevalence, higher UI severity, and less UI-associated QoL. Methods: Medical records in a tertiary referral hospital were used to contact patients who had experienced a stroke between 6 to 32 months before the study date. The patients were given the International Consultation on Incontinence Questionnaire Short Form (ICIQ-UI-SF) questionnaire for determining the presence of UI and its severity. UI-positive patients were then given the I-QOL questionnaire to determine their QoL. Results: The prevalence of UI in our study population (n=189) was 31%. Older age at the time of stroke was a...
IntroductionPeripheral neuropathy is a dose-limiting adverse effect of oxaliplatin. The aim of this study was to evaluate the efficacy and safety of duloxetine in the prevention of oxaliplatin-induced peripheral neuropathy... more
IntroductionPeripheral neuropathy is a dose-limiting adverse effect of oxaliplatin. The aim of this study was to evaluate the efficacy and safety of duloxetine in the prevention of oxaliplatin-induced peripheral neuropathy (OIPN).MethodCancer patients receiving oxaliplatin chemotherapy were randomized into two arms. Duloxetine 60 mg capsule was given in the first 14 days of each chemotherapy cycle to one arm and placebo was similarly given to another arm. We compared the two arms based on the incidence of neuropathy and the results of the nerve conduction study.ResultsThirty two patients were randomized to duloxetine and placebo arms. Most of the patients had rectal cancer (90.6%). Compared with the placebo arm, patients in the duloxetine arm had a lower percentage of chemotherapy cycles (mean) in which they reported distal paresthesia (84% vs. 51%, P = 0.01) and throat discomfort (69% vs. 37%, P = 0.01). There was no difference in the percentage of cycles in which patients reported...
BackgroundSpinal cord injury (SCI) is a catastrophic event that influences all aspects of the life of the patients and their families. It may have many acute or chronic complications. One of the most common complications is shoulder pain,... more
BackgroundSpinal cord injury (SCI) is a catastrophic event that influences all aspects of the life of the patients and their families. It may have many acute or chronic complications. One of the most common complications is shoulder pain, which particularly occurs in wheelchair users.ObjectivesThis study aimed to estimate the prevalence of shoulder pain in paraplegic spinal cord injury patients who were referred to our clinic.MethodsWe included 70 spinal cord injury patients in our study according to inclusion criteria. Demographic data and SCI-related factors were recorded. The disabilities of the arm, shoulder, and hand (DASH) questionnaire was used to assess shoulder pain in our patients.ResultsMean score of pain was 51 in cervical, 23 in thoracic and 12 in lumbar spinal cord injury according to the DASH questionnaire. The pain was more prevalent and severe in the cervical group.ConclusionsAccording to our study, it seems that shoulder pain has a relatively high prevalence and is more severe in cervical quadriplegic SCI patients that may be due to muscle imbalance around the shoulder. Therefore, this problem should be noted in the course of managing these patients.
Purpose: To determine the serum levels of vitamin D and calcium in patients with spinal cord injuries and their association with the scope of the lesion and the time passed since its inception. Materials and Methods: The participants were... more
Purpose: To determine the serum levels of vitamin D and calcium in patients with spinal cord injuries and their association with the scope of the lesion and the time passed since its inception. Materials and Methods: The participants were 147 spinal cord injured patients with the required criteria who had referred to our center. A questionnaire was filled for all of them to gather demographic details and then they were examined by a specialist. Blood sample was taken to determine the serum level of their 25-hydroxy vitamin D. Results: The mean of calcium and vitamin D serum levels were 8.33 mg/dL and 15.30 ng/mL, respectively. Of the participants, 64.6% had vitamin D deficiency and 18.4% had insufficient level of vitamin D. Only in 7.5% of the patients the level of vitamin D was sufficient. In addition, 50.3% of the participants were afflicted with hypocalcaemia and the rest had normal level of calcium. Conclusion: According our study many of spinal cord injured patients suffer from vitamin D deficiency. Considering the major complications caused by deficiency of vitamin D, prevention and treatment of this complication appears to be crucial in such patients
Objective The Hereditary Sensory and Autonomic neuropathy (HSAN) is a rare group of neuropathies that affects the Sensory and Autonomic nervous system. The patients do not have the ability of sensing different sensations such as pain and... more
Objective The Hereditary Sensory and Autonomic neuropathy (HSAN) is a rare group of neuropathies that affects the Sensory and Autonomic nervous system. The patients do not have the ability of sensing different sensations such as pain and temperature, which tends to lead to different injuries. In addition, due to autonomic involvement, the patients suffer from fluctuation in body temperature periodically and lack of precipitation. HSAN is divided into 5 types according to the age of onset, clinical features, and inheritance. Our case was a 9-yr old boy from cousin parents. He had some developmental delay and history of recurrent fever and convulsion in the first year of his life. Gradually, other symptoms added to patient’ feature such as multiple painless skin ulcers, tooth loss, destruction of toes and fingers. In electrodiagnostic study, we found decreased amplitude of sensory nerves, while the other studies were normal. Laboratory test and imaging studies were also normal. All cl...
Abstract Introduction Shoulder pain is one of the common musculoskeletal complaints of the patients with spinal cord injury. Corticosteroid injection to the subacromial bursa is one of the confirmed therapies which can be guided by... more
Abstract Introduction Shoulder pain is one of the common musculoskeletal complaints of the patients with spinal cord injury. Corticosteroid injection to the subacromial bursa is one of the confirmed therapies which can be guided by anatomic landmarks or ultrasound. This study is aimed to compare these two methods to find the one with the highest therapeutic impact. Materials and methods In this study, 30 patients with paraplegic SCI suffering from shoulder pain were enrolled. They were divided into 2 groups based on 4-block randomization sampling. The first group received subacromial corticosteroid injection through anatomic landmarks; while in the second group, the injection was guided by ultrasound. VAS criterion was employed for investigation of pain severity; while the constant score was used to study the shoulder pain and function. BREF questionnaire was also applied to examine the quality of life. Findings The mean scores of VAS and Constant in both groups showed a significant improvement two months after intervention when compared with their condition before the intervention. This improvement was significantly higher in the ultrasound group. The physical, physiological and environmental health scores of BREF questionnaire as well as their total score showed a significant improvement in both groups two months after intervention. But this improvement was not significantly different between the two groups in terms of any of the items. Discussion Hence, although ultrasound-guided injection is more costly and requires higher skills in comparison with blind injection, it is significantly more effective in controlling the pain and improving the shoulder function.
Objective The Hereditary Sensory and Autonomic neuropathy (HSAN) is a rare group of neuropathies that affects the Sensory and Autonomic nervous system. The patients do not have the ability of sensing different sensations such as pain and... more
Objective The Hereditary Sensory and Autonomic neuropathy (HSAN) is a rare group of neuropathies that affects the Sensory and Autonomic nervous system. The patients do not have the ability of sensing different sensations such as pain and temperature, which tends to lead to different injuries. In addition, due to autonomic involvement, the patients suffer from fluctuation in body temperature periodically and lack of precipitation. HSAN is divided into 5 types according to the age of onset, clinical features, and inheritance. Our case was a 9-yr old boy from cousin parents. He had some developmental delay and history of recurrent fever and convulsion in the first year of his life. Gradually, other symptoms added to patient' feature such as multiple painless skin ulcers, tooth loss, destruction of toes and fingers. In electrodiagnostic study, we found decreased amplitude of sensory nerves, while the other studies were normal. Laboratory test and imaging studies were also normal. Al...
Even though dehydration could aggravate formation of urinary calculi, the effects of fluid and food restriction on calculus formation is not thoroughly defined. The purpose of this study is to evaluate the effects of fluid and food... more
Even though dehydration could aggravate formation of urinary calculi, the effects of fluid and food restriction on calculus formation is not thoroughly defined. The purpose of this study is to evaluate the effects of fluid and food restriction in Ramadan fasting on urinary factors in kidney and urinary calculus formation. Fifty-seven men aged 30 to 55 years old, including 37 recurrent calcium calculus formers and 20 with no history of kidney calculi were evaluated for blood tests, ultrasonography investigations, urinalysis, urine culture, and also 24-hour urine collection test. Metabolites including calcium, oxalate, citrate, uric acid, magnesium, phosphate, potassium, sodium, and creatinine were measured before and during Ramadan fasting. The values of calculus-precipitating solutes as well as inhibitory factors were documented thoroughly. Total excretion of calcium, phosphate, and magnesium in 24-hour urine and also urine volume during fasting were significantly lower than those i...
In this study the full sequence of the calcitonin receptor gene (CALCR) in a group of Iranian males suffering from recurrent calcium urinary stones was compared with that of a control group. Serum and urinary biochemistry related to... more
In this study the full sequence of the calcitonin receptor gene (CALCR) in a group of Iranian males suffering from recurrent calcium urinary stones was compared with that of a control group. Serum and urinary biochemistry related to urolithiasis were evaluated in 105 males diagnosed with recurrent kidney calcium stones and 101 age-matched healthy control males. The polymerase chain reaction single-strand conformation polymorphism method was used to detect new polymorphisms in the CALCR. Nine polymorphisms were detected; seven were in the non-coding and two in the coding region. The T allele associated with the 3'UTR+18C>T polymorphism was observed exclusively in the stone formers. The exact odds ratio for the T allele in this locus for those at risk of stone formation was 36.72 (95% CI 4.95-272.0) (p < 0.001). The mean (standard deviation) urine calcium concentration was 117 (60) mg/l in patients with the C allele and 152 (72) mg/l in those with the T allele (p = 0.03). In addition, IVS1-6T>C and IVS1insA polymorphisms in intron 1 were associated with kidney stone disease (p < 0.001). Regarding single nucleotide polymorphism 447, mean (standard deviation) of serum calcitonin levels were 16.7 (18.7) pg/ml, 10.5 (11.0) pg/ml and 9.94 (9.7) pg/ml in subjects with TT, TC and CC genotypes, respectively (p = 0.01). Our data indicate a potential association between 3'UTR+18C>T and intron 1 polymorphisms in the CALCR and the risk of kidney stone disease.
Comprehensive sequencing of the coding exons of the calcium-sensing receptor gene (CASR) was performed in a group of Iranian recurrent calcium kidney stone-formers and the results were compared with a control group. Serum and urine... more
Comprehensive sequencing of the coding exons of the calcium-sensing receptor gene (CASR) was performed in a group of Iranian recurrent calcium kidney stone-formers and the results were compared with a control group. Serum and urine parameters were evaluated in 99 males aged between 30 and 55 years old with idiopathic recurrent calcium urolithiasis and in 107 men as a control group. Products of polymerase chain reaction were sequenced using forward primer until a mutation was found in that exon. Then, other cases were analysed by single-strand conformation polymorphism. Four polymorphisms were detected in CASR exons, all in the coding region of exon 7. These polymorphisms and their minor allele frequency were P748P (100%), A986S (1%), R990G (3%) and E1011Q (98%). There was a significantly higher count of 986S (p = 0.006), 990G (p = 0.006) and E1011 (p = 0.02) alleles in patients. The odds ratio (95% confidence interval) was 2.55 (1.31-4.96) in those at risk of stone disease for the 986S allele and 8.06 (1.80-35.9) for the 990G allele. Men with the RR genotype at R990G showed a significantly higher serum ionized calcium than the RG or GG group (p = 0.03). A significantly lower serum total calcium was found in subjects with the QQ than the EQ genotype with respect to the 1011 locus (p = 0.005). Furthermore, the 1011Q allele was marginally associated with hypercalciuria (p = 0.05). The 986S, 990G and 1011Q alleles were associated with a recurrent calcium kidney stone-forming state. 986S and 1011Q alleles, but not 986S, were associated with hypercalcaemia.
This study was designed to assess sexual dysfunction in women suffering from type 2 diabetes mellitus. Forty-five type 2 diabetic, non-menopausal married women, aged 20-55 years, who were referred to Shahid Labbafinejad Clinics from March... more
This study was designed to assess sexual dysfunction in women suffering from type 2 diabetes mellitus. Forty-five type 2 diabetic, non-menopausal married women, aged 20-55 years, who were referred to Shahid Labbafinejad Clinics from March 2008 to June 2009 were included in this study. They were compared to 91 non-diabetic volunteers. Sexual function was evaluated by the sexual function questionnaire. Genitourinary examination was performed in all subjects. Blood sample tests were requested for fasting blood sugar, hemoglobin A(1c), 2-hour postprandial glucose and lipid profile measurements. Ophthalmologic and neurologic examinations (checking deep tendon reflexes) were done for cases. The mean age of cases and controls was 42.17± 5.91 and 34.96 ± 8.30 years, respectively (p < 0.001). The prevalence of a high probability of female sexual dysfunction in 6 domains including desire, arousal sensation, arousal lubrication, orgasm, pain and enjoyment was 71.1, 84.4, 55.6, 71.1, 8.9 and 66.7% in the diabetes mellitus women and 56.6, 67.0, 59.3, 57.1, 25.3 and 53.8% in the non-diabetic volunteers, respectively. Differences were statistically significant in the 3 domains of desire, arousal sensation and pain (p < 0.05). Deep tendon reflexes were normal in all and 12.5% showed diabetic retinopathy. Sexual dysfunction in cases as well as in controls was high; however, further studies with a higher number of patients are needed to confirm the results.
ABSTRACT
BACKGROUND Exercise has been demonstrated to be safe and well-tolerated in individuals with multiple sclerosis (MS). Physical activity has been shown to enhance the therapeutic effects of transcranial direct current stimulation (tDCS).... more
BACKGROUND Exercise has been demonstrated to be safe and well-tolerated in individuals with multiple sclerosis (MS). Physical activity has been shown to enhance the therapeutic effects of transcranial direct current stimulation (tDCS). This study aimed to determine the efficacy of intermittent tDCS combined with riding a stationary bicycle to improve walking capacity in individuals with MS. METHODS This double-blind randomized controlled trial enrolled 50 eligible participants. Thirty-nine participants completed the study: 21 in the active group and 18 in the control group. Participants were assigned randomly to exercise on a stationary bike in conjunction with anodal tDCS or to exercise combined with a sham tDCS protocol. Walking capacity tests (2-Minute Walk Test, 5-Meter Walk Test, Timed Up and Go test), manual muscle testing, the Fatigue Severity Scale, and the Multiple Sclerosis Quality of Life–54 were used to determine outcomes. RESULTS In terms of observed changes in 2-Minute...
Purpose: To evaluate different urinary factors contributing to idiopathic calcium stone disease for determining appropriate medical treatments. Materials and Methods: Two 24-hour urine samples were collected from 106 male recurrent... more
Purpose: To evaluate different urinary factors contributing to idiopathic calcium stone disease for determining appropriate medical treatments. Materials and Methods: Two 24-hour urine samples were collected from 106 male recurrent idiopathic calcium stone formers and another 109 randomly selected men as the control group matching for age. Results: Cases had significantly higher mean urine oxalate, calcium, uric acid, and chloride in comparison with the healthy controls (P < .001). After necessary adjustment, only mean urine levels of oxalate and uric acid were higher in stone formers than those in controls. The mean value of supersaturation for calcium oxalate was significantly higher in patients than the controls (P = .001); whereas supersaturation for calcium phosphate and uric acid did not reach statistical significe (P = .675 and P = .675, respectively). Hyperoxaluria and hypercalciuria were among the most frequent abnormalities. After categorizing urine parameter values int...
Damage to the brachial plexus branches is one of the most important events during traumatic events, which may cause various disabilities. Electrodiagnostic testing is the preferred method to evaluate the extent of damage to the brachial... more
Damage to the brachial plexus branches is one of the most important events during traumatic events, which may cause various disabilities. Electrodiagnostic testing is the preferred method to evaluate the extent of damage to the brachial plexus following trauma. The case presented in this paper, is a 26-year-old man who had near normal function of pronator teres and flexor carpi radialis muscles on electrodiagnostic testing following a right upper limb severe blunt injury at the level of his arm. After surgical investigation, we found a rare variation in the proximal part of the median nerve. In this case, branches to the pronator teres muscle and flexor carpi radialis had emerged from the proximal section of the median nerve in the arm region. This new variation holds important clinical implications especially in trauma patients presenting with weakness in forearm flexion.
Background: Carpal tunnel syndrome (CTS) is the most common neuropathy caused by nerve compression. The “double crush syndrome” (DCS) theory suggests the coexistence of CTS and cervical radiculopathy (CR). Studies on DCS have focused... more
Background: Carpal tunnel syndrome (CTS) is the most common neuropathy caused by nerve compression. The “double crush syndrome” (DCS) theory suggests the coexistence of CTS and cervical radiculopathy (CR). Studies on DCS have focused mainly on nerve damage in the proximal part and, subsequently, vulnerability of the distal part of the nerve to injuries, in particular, entrapment. There are few studies on the presence of distal injury following the vulnerability of the proximal portion. Therefore, the current study deals with the evaluation of the simultaneous presence of CR in patients with CTS. Methods: This retrospective study was performed on 309 upper limb electromyography (EMG) records of patients with CTS. These patients referred to the physical medicine and rehabilitation clinic of Imam Khomeini Hospital, Tehran, Iran, during 2016 to 2019 with complaints of neck pain or tingling hands to have an EMG. The demographic data and EMG findings were analyzed using SPSS software. Res...
Spinal manipulation is a manual technique commonly used for the treatment of low back pain. The physiologic mechanisms of the spinal manipulation are largely unknown. One basic physiologic response for spinal manipulation is an alteration... more
Spinal manipulation is a manual technique commonly used for the treatment of low back pain. The physiologic mechanisms of the spinal manipulation are largely unknown. One basic physiologic response for spinal manipulation is an alteration in motoneuronal activity, as assessed by the Hoffmann reflex (H-reflex) technique. The purpose of this study was to determine the effect of spinal manipulation on the amplitude and onset latency of H-reflex and on H/M amplitude ratio in patients with low back pain. Fifty-Eight patients with low back pain aged between 20-60 years, who had no exclusion criteria were included. Tibial nerve H-reflex and M wave were recorded before and after Lumbosacral spinal manipulation. Lumbosacral manipulation significantly decreased the amplitude of the H-reflex and H/M amplitude ratio (P<0.05). It had no significant effect on H-reflex latency or M wave amplitude and latency (P>0.05). Lumbosacral manipulation produces attenuation of alpha motoneuronal excita...
Background: Carpal tunnel syndrome (CTS) is the most common focal mononeuropathy. It causes characteristic symptoms, including numbness and paresthesia in hand due to median nerve compression at the wrist. Objectives: We aimed to... more
Background: Carpal tunnel syndrome (CTS) is the most common focal mononeuropathy. It causes characteristic symptoms, including numbness and paresthesia in hand due to median nerve compression at the wrist. Objectives: We aimed to investigate CTS prevalence and personal, psychosocial, biomedical, and occupational factors related to it comprehensively, according to scattered publications, without the simultaneous evaluation of all CTS risk factors. Methods: A total of 345 patients referred to a hand clinic with a complaint of paresthesia in upper extremities and suspected CTS. The patients underwent neurological assessment and electrodiagnostic (EDX) tests to confirm the diagnosis. The demographic information, past medical history, past trauma history, and occupational history of all the patients were recorded and finally analyzed with SPSS software. Results: Of the patients, 213 (67.1%) met the criteria for CTS, of whom 160 (75%) were female. Females were significantly more affected ...
The prevalence of osteoporosis is reported differently. We designed this systematic review and meta-analysis to estimate pooled prevalence of osteoporosis and osteopenia in patients with MS. Independently, two researchers searched PubMed,... more
The prevalence of osteoporosis is reported differently. We designed this systematic review and meta-analysis to estimate pooled prevalence of osteoporosis and osteopenia in patients with MS. Independently, two researchers searched PubMed, Scopus, EMBASE, Web of Science, and google scholar along with gray literature (conference abstracts and references of the references) up to March 2021. We collected data regarding first author, country of origin, number of enrolled patients, number cases with osteoporosis/ osteopenia, mean age, F/M ratio, mean EDSS, and mean duration of the disease. Literature search revealed 847 articles and 658 remained after deleting duplicates. Finally, 29 original articles and 6 conference papers remained for meta-analysis. A total of 13,906 patients were evaluated. The pooled prevalence of osteoporosis was 17% (95% CI: 14–20%) (I2 = 90.4%, p < 0.001). The pooled prevalence of osteopenia was 43% (95% CI: 35–51%) (I2 = 97.9%, p < 0.001). Osteoporosis/oste...
There is no knowledge on the outcome of renal transplant for end-stage renal disease secondary to neurogenic bladder caused by spinal cord injury. In this study, we evaluated the outcome of kidney allograft recipients with spinal cord... more
There is no knowledge on the outcome of renal transplant for end-stage renal disease secondary to neurogenic bladder caused by spinal cord injury. In this study, we evaluated the outcome of kidney allograft recipients with spinal cord injury. We evaluated graft survival, clinical course, laboratory findings, and imaging studies in 21 men (veterans) with spinal cord injury and renal failure secondary to neurogenic bladder. They underwent renal transplant between 1990 and 2006. Bladder dysfunction was appropriately managed before or with receiving the kidney allograft. Mean (-/+ SD) age of patients was 43.8 -/+ 5.9 years. Mean glomerular filtration rate at the closing date of the study was 89.5 -/+ 33.6 mL/min. During follow-up (median: 6 years, range: 1-17 years), mean duration of graft survival was 15.4 -/+ 1.0 years (95% confidence interval, 13.2-17.5 years). Following renal transplant, mean nadir level of serum creatinine was 74.25 -/+ 16.79 micromol/L (0.84 -/+ 0.19 mg/dL). Six p...
To evaluate different urinary factors contributing to idiopathic calcium stone disease for determining appropriate medical treatments. Two 24-hour urine samples were collected from 106 male recurrent idiopathic calcium stone formers and... more
To evaluate different urinary factors contributing to idiopathic calcium stone disease for determining appropriate medical treatments. Two 24-hour urine samples were collected from 106 male recurrent idiopathic calcium stone formers and another 109 randomly selected men as the control group matching for age. Cases had significantly higher mean urine oxalate, calcium, uric acid, and chloride in comparison with the healthy controls (P < .001). After necessary adjustment, only mean urine levels of oxalate and uric acid were higher in stone formers than those in controls. The mean value of supersaturation for calcium oxalate was significantly higher in patients than the controls (P = .001); whereas supersaturation for calcium phosphate and uric acid did not reach statistical significance (P = .675 and P = .675, respectively). Hyperoxaluria and hypercalciuria were among the most frequent abnormalities. After categorizing urine parameter values into four quartiles, the risk of stone fo...
عفانم ضراعت : تسا هدشن ملاعا بط هب هک تسا یکشزپ یمیدق شور کی ینزوس روط رارق هدافتسا دروم عیاش یـم درـیگ . نـیا هدافتسا هک تسا لاس رازه ود زا شیب يارب نیچ رد شور یم دوش . رد ینزوـس بـط اـب نامرد مه و مدرم نیب هـجوت دروـم ،یمسج تلالاتخا زا... more
عفانم ضراعت : تسا هدشن ملاعا بط هب هک تسا یکشزپ یمیدق شور کی ینزوس روط رارق هدافتسا دروم عیاش یـم درـیگ . نـیا هدافتسا هک تسا لاس رازه ود زا شیب يارب نیچ رد شور یم دوش . رد ینزوـس بـط اـب نامرد مه و مدرم نیب هـجوت دروـم ،یمسج تلالاتخا زا یعیسو فیط يارب تملاس ناصصختم نینچ تسا هتفرگ رارق یناوارف . ا زا شور نی نایرج میظنت قیرط » یچ « ) ندب رد یتایح يژرنا ( ثعاب ، یم يدوبهب دوش . هتشر رد ینزوس بط ي تسوپ ًاریخا هب شور زا یکی ناونع ياه ناوج و يزاس نامرد ،تروص كورچ و نیچ هچیهام نوت اه و یناسشک نآ اه تسا هدش هئارا . زا ینزوـس بط کشزپ طیارش زا یعیسو فیط نامرد يارب هدافتسا یتسوپ تلالاتخا هلمجزا ،ی یـم دوـش . شور نزوس زا هک تسا تروص نیا هب راک ياه طاـقن و نیدـیرم طوـطخ دادتما رد لیرتسا و کچوک ینزوس بط دنوش یحاون نیا رد نوخ شدرگ شیازفا ثعاب ات هدش هدافتسا . ییابیز ینزوس بط ًلاماک نامرد کی اـک نآ فده هک تسا يریپ دض عماج و یعیبط كورـچ و طوـطخ شه ياـه تسا تروص . مسیناکم هلمجزا تسا هدش حرطم ییابیز ینزوس بط يارب يددعتم ياه شیازفا تلاضع نوت ندنادرگزاب و تروص تلاضع ششک . مه نیـنچ و تـبوطر شیازـفا زا ي...
Background: Bladder, bowel, and sexual dysfunction are among common complications in patients with multiple sclerosis (MS). These complications could affect the quality of life. The goal of this study is to assess bowel, bladder, and... more
Background: Bladder, bowel, and sexual dysfunction are among common complications in patients with multiple sclerosis (MS). These complications could affect the quality of life. The goal of this study is to assess bowel, bladder, and sexual dysfunction and quality of life in married women with MS. Methods: One hundred and twenty-seven married women with MS were enrolled. They fill the valid and reliable Persian version of the Female sexual function index (FSFI), SF-36, Bladder Control Scale (BLCS), and The Bowel Control Scale (BWCS). Results: Mean age and disease duration were 38±7.9 and 8.4±6.5 years, respectively. There was significant negative correlation between SF-36 and BWCS (r=-0.25, p=0.001) and BLCS (r=-0.36, p=0.001) and significant positive correlation between FSFI and SF-36(r=0.27, p=0.004). There was a significant negative correlation between age and total FSFI (r=-0.34, p<0.001) and also between EDSS and FSFI (r=-0.21, p=0.01). By considering 26.55 as the cut-off point of FSFI, we found that women with sexual dysfunction had a more impaired quality of life and more bowel control problems. Linear regression analysis showed that EDSS and BLCS are independent predictors of SF-36. Conclusion: Bowel/bladder and sexual dysfunction have negative impacts on the quality of life in women with multiple sclerosis.
ايژلاتون سيد كي اكيتتسراپ اـب كـيتاپورون يزتـسا شنم أ ب هك تسا هتخانشان ه يسـح يتاـپورون كي ناونع هخاـش ياـه يعاـخن باصـعا يـفلخ T2-T6 هتخانـش يم دوش . يزتـسراپ اـي شراخ لماش يراميب تاصخشم هيشاح ي هـبل يناتحت ي لاوپاكـسا يـلخاد تـسا .... more
ايژلاتون سيد كي اكيتتسراپ اـب كـيتاپورون يزتـسا شنم أ ب هك تسا هتخانشان ه يسـح يتاـپورون كي ناونع هخاـش ياـه يعاـخن باصـعا يـفلخ T2-T6 هتخانـش يم دوش . يزتـسراپ اـي شراخ لماش يراميب تاصخشم هيشاح ي هـبل يناتحت ي لاوپاكـسا يـلخاد تـسا . نـيا لاس رد ادتبا يراميب 1934 تسـيژولورون كـي طـسوت دش هداد حرش يسور . باصـعا هـب بيـسآ اـي كـيرحت هسفق هنيس هب شش ات ود يا ناـيب هعياـض تـلع ناوـنع يم تـسا هدشـن هتخانـش بيـسآ قيقد ناكم اما ،دوش . هنيـس يتاـپولوكيدار يـلپ تاـعلاطم بـلغا هـب يا تـلع هدرشف ار يتشـپ تارـقف نوتس باصعا ندش هـب ناوـنع راخ يلصا تلع يفرعم ش يم و دـننك هـيقب ي تلااـقم ، هيواز شيازفا ي زا يسـح يبصـع ربيف ذوفن و كيموتانآ نآ فارـطا تلاضـع نايم يـفرعم هـضراع نـيا تـلع ار يم دننك . ايژلاتون اكيتتسراپ ًلاومعم هدـيد نسم نانز رد يم كي ،دوش و تسا هفرط يم هام يارب دناوت لاس ات اه اه دباي همادا . هعياض چيه ي وا هيل ي درادـن دوجو يتسوپ و هدـيد نمزـم شراـخ زا يـشان هـيوناث تارـييغت اـهنت هديس يوضر يماما ارهز ينيسح ميرم يراودازآ هثدحم
Overactive bladder (OAB) is defined as bladder storage dysfunction, which results in a frequent and sudden urge to urinate. OAB is a prevalent disorder, and its symptoms have a detrimental effect on health-related quality of life and... more
Overactive bladder (OAB) is defined as bladder storage dysfunction, which results in a frequent and sudden urge to urinate. OAB is a prevalent disorder, and its symptoms have a detrimental effect on health-related quality of life and increase social problems. Treatment of OAB includes first-line behavioral therapies and second-line anti-muscarinic drugs. However, the rate of drug discontinuation due to drug side effects is high. Acupuncture is considered an effective therapy to suppress contractions and excessive detrusor muscle activity, improve bladder adaptation, maintain normal urination, and improve pathological changes in bladder tissue based on several preclinical and clinical investigations. Therefore, as one of the complementary and alternative medicine methods, acupuncture can play a pivotal role in the treatment of patients with OAB.
A 56-year-old woman with hands paresthesia referred to the physical  medicine and rehabilitation Clinic of Imam Khomeini Hospital. Based on  physical examination and electrodiagnosis, the patient had bilateral  moderate carpal tunnel... more
A 56-year-old woman with hands paresthesia referred to the physical  medicine and rehabilitation Clinic of Imam Khomeini Hospital. Based on  physical examination and electrodiagnosis, the patient had bilateral  moderate carpal tunnel syndrome with greater intensity in the right side.  Wrist splint and acupuncture were prescribed for the patient. 20 sessions of  acupuncture were done every other day. At the end of treatment, the  patient’s clinical symptoms and electrodiagnostic findings improved, and  there was only mild carpal tunnel syndrome in her right hand. It seems that  acupuncture can be an effective treatment for carpal tunnel syndrome.  Considering its few complications, acupuncture can be used to treat mild to  moderate carpal tunnel syndrome.
INTRODUCTION Even though dehydration could aggravate formation of urinary calculi, the effects of fluid and food restriction on calculus formation is not thoroughly defined. The purpose of this study is to evaluate the effects of fluid... more
INTRODUCTION Even though dehydration could aggravate formation of urinary calculi, the effects of fluid and food restriction on calculus formation is not thoroughly defined. The purpose of this study is to evaluate the effects of fluid and food restriction in Ramadan fasting on urinary factors in kidney and urinary calculus formation. MATERIALS AND METHODS Fifty-seven men aged 30 to 55 years old, including 37 recurrent calcium calculus formers and 20 with no history of kidney calculi were evaluated for blood tests, ultrasonography investigations, urinalysis, urine culture, and also 24-hour urine collection test. Metabolites including calcium, oxalate, citrate, uric acid, magnesium, phosphate, potassium, sodium, and creatinine were measured before and during Ramadan fasting. The values of calculus-precipitating solutes as well as inhibitory factors were documented thoroughly. RESULTS Total excretion of calcium, phosphate, and magnesium in 24-hour urine and also urine volume during fa...
BACKGROUND Multiple considerations should be taken before standardizing a clinical procedure such as efficacy, safety, or the cost. The aim of this study was to compare the effects of landmark-guided vs ultrasonography-guided... more
BACKGROUND Multiple considerations should be taken before standardizing a clinical procedure such as efficacy, safety, or the cost. The aim of this study was to compare the effects of landmark-guided vs ultrasonography-guided intra-articular injection of corticosteroid into the first metatarsophalangeal joint cavity to reduce pain and dysfunction in patients with hallux rigidus. METHODS We carried out a single-blind randomized controlled trial with 2 parallel arms in an outpatient clinic affiliated with a medical university. In total, 50 participants (35 women) with the mean (SD) age of 49.8 (10.3) years were randomly allocated to landmark-guided or ultrasonography-guided groups (each n = 25). Each patient received a single intra-articular injection of 40-mg methylprednisolone plus 1 mL lidocaine into the affected first metatarsophalangeal joint. The primary outcome was joint pain and the secondary outcome was the American Orthopaedic Foot & Ankle Society score. We measured the outc...
Introduction: Diagnosing an osteoid osteoma as a benign tumor can be challenging owing to its different presentation patterns, ambiguous radiological findings and unusual sites of involvement. The present case report involves a... more
Introduction: Diagnosing an osteoid osteoma as a benign tumor can be challenging owing to its different presentation patterns, ambiguous radiological findings and unusual sites of involvement. The present case report involves a 30-year-old female patient with a large osteoid osteoma of the thoracic vertebrae as an uncommon site of its presentation. Case Presentation: The patient presented with a one-year history of progressive right-sided upper back and interscapular pains. She was identified as a candidate for surgery using the whole body bone scan and a multiple detector computed tomography (MDCT) scan. A large 25-mm osteoid osteoma of the lamina of the third thoracic vertebra (T3) was also diagnosed through histopathology. Conclusion: As a potential cause of persistent back pain in young adults, an osteoid osteoma may be easily missed by routine radiographs. The CT scan is an effective tool in the investigation of the size and location of this tumor. Surgical excision can also be...
BACKGROUND: The objective was to evaluate an innovative physical medicine and rehabilitation (PMR) course for undergraduate students of Tehran University of Medical Sciences and their attitude and knowledge change following course... more
BACKGROUND: The objective was to evaluate an innovative physical medicine and rehabilitation (PMR) course for undergraduate students of Tehran University of Medical Sciences and their attitude and knowledge change following course participation. MATERIALS AND METHODS: Ninety-one medical students filled the knowledge, attitude, and satisfaction forms pre- and postintervention. Nineteen medical students, two faculty physiatrists, two residents, two physical therapists, and two occupational therapists participated in the focus groups. RESULTS: We found significant attitude improvements. They declared the usefulness of PMR course for undergraduate. Moreover, they agreed that physiatrists could be first choice for refer of musculoskeletal patients and they preferred PMR as future career after course experience. Also, they preferred to refer musculoskeletal patients including carpal tunnel syndrome, frozen shoulder, nonspecific low back pain after course participation. We found a good rel...

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