Maropitant

Maropitant
(IUPAC) ime
	(7R,8S)-N-[(5-tert-Butil-2-metoksifenil)metil]-7-[di(fenil)metil]-1-azabiciklo[2.2.2]oktan-8-amin
Klinički podaci
Identifikatori
ATCvet kod	QA04AD90
PubChem	23724948
ChemSpider	176804
Hemijski podaci
Formula	C32H40N2O
Mol. masa	468,67 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C32H40N2O.C6H8O7.H2O/c1-32(2,3)27-15-16-28(35-4)26(21-27)22-33-30-25-17-19-34(20-18-25)31(30)29(23-11-7-5-8-12-23)24-13-9-6-10-14-24;7-3(8)1-6(13,5(11)12)2-4(9)10;/h5-16,21,25,29-31,33H,17-20,22H2,1-4H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2/t30-,31-;;/m0../s1 ; Key: PGVSXRHFXJOMGW-YBZGWEFGSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	samo za veterinarsku upotrebu
Način primene	Oralno, supkutano

Maropitant (Cerenia (SAD)), se koristi kao maropitant citrat (USAN), je antagonist NK₁ receptora. Nega je razvila kompanija Pfizer Zdravlje Životinja specifično za lečenje bolesti kretanja i povraćanja kod pasa. On je je odobren od strane FDA samo za upotrebu kod pasa.^[4] Ovaj lek je odobren februara 2007. Prodaje se pod imenom Cerenia.

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ „Cerenia (maropitant citrate) Injectable Solution, Dogs” (pdf). Pristupljeno 19. 04. 2011.

Povezano

Spoljašnje veze

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[urlwww.fda.gov-4] „Cerenia (maropitant citrate) Injectable Solution, Dogs” (pdf). Pristupljeno 19. 04. 2011.

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