Amilaza

Amilaza je enzim koji katalizuje razlaganje skroba u šećere. Amilaza je prisutna u ljudskoj pljuvački, gde ona započinje hemijski proces varenja. Hrana koja sadrži znatan udeo skroba i malo šećera, kao što su pirinač i krompir, ima blago sladak ukus tokom žvakanja jer amilaza pretvara deo njenog skroba u šećer u ustima. Pankreas takođe pravi amilazu (alfa amilaza) koja hidrolijuje skrob u disaharide i trisaharide. Njih dalje konvertuju drugi enzimi do glukoze radi telesnog snabdevanja energijom. Biljke i neke bakterije takođe proizvode amilazu. Kao diastaza, amilaza je bila prvi enzim koji je otkrio i izolovao Anselm Pajien 1833.^[1] Specifičnni amilazni proteini se obeležavanju grčkim slovima. Sve amilaze su glikozidne hidrolaze i deluju na α-1,4-glikozidne veze.

Reference

↑ (1) Robert Hill and Joseph Needham, The Chemistry of Life: Eight Lectures on the History of Biochemistry (London, England: Cambridge University Press, 1970), page 17 ; (2) Richard B. Silverman, The Organic Chemistry of Enzyme-catalyzed Reactions, 2nd ed. (London, England: Academic Press, 2002), page 1 ; (3) Jochanan Stenesh, Biochemistry, vol. 2 (New York, New York: Plenum, 1998), page 83 ; (4) Robert A. Meyers, ed., Molecular Biology and Biotechnology: A Comprehensive Desk Reference (New York, New York: Wiley-VCH, 1995), page 296.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

Molecule of the month February 2006 Arhivirano 2011-01-19 na Wayback Machine-u
Nutrition Sciences 101 Arhivirano 2007-02-24 na Wayback Machine-u

[1] (1) Robert Hill and Joseph Needham, The Chemistry of Life: Eight Lectures on the History of Biochemistry (London, England: Cambridge University Press, 1970), page 17 ; (2) Richard B. Silverman, The Organic Chemistry of Enzyme-catalyzed Reactions, 2nd ed. (London, England: Academic Press, 2002), page 1 ; (3) Jochanan Stenesh, Biochemistry, vol. 2 (New York, New York: Plenum, 1998), page 83 ; (4) Robert A. Meyers, ed., Molecular Biology and Biotechnology: A Comprehensive Desk Reference (New York, New York: Wiley-VCH, 1995), page 296.

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