DNA Breaks, Double-Stranded
"DNA Breaks, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruptions in the sugar-phosphate backbone of DNA, across both strands adjacently.
| Descriptor ID |
D053903
|
| MeSH Number(s) |
G05.200.210.220
|
| Concept/Terms |
DNA Breaks, Double-Stranded- DNA Breaks, Double-Stranded
- Break, Double-Stranded DNA
- Breaks, Double-Stranded DNA
- DNA Break, Double-Stranded
- DNA Breaks, Double Stranded
- Double-Stranded DNA Break
- Double Stranded DNA Break
- Double-Strand DNA Breaks
- Break, Double-Strand DNA
- Breaks, Double-Strand DNA
- DNA Break, Double-Strand
- DNA Breaks, Double-Strand
- Double Strand DNA Breaks
- Double-Strand DNA Break
- Double-Stranded DNA Breaks
- Double Stranded DNA Breaks
|
Below are MeSH descriptors whose meaning is more general than "DNA Breaks, Double-Stranded".
Below are MeSH descriptors whose meaning is more specific than "DNA Breaks, Double-Stranded".
This graph shows the total number of publications written about "DNA Breaks, Double-Stranded" by people in this website by year, and whether "DNA Breaks, Double-Stranded" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 3 | 5 |
| 2007 | 8 | 3 | 11 |
| 2008 | 11 | 11 | 22 |
| 2009 | 9 | 9 | 18 |
| 2010 | 14 | 10 | 24 |
| 2011 | 10 | 8 | 18 |
| 2012 | 9 | 10 | 19 |
| 2013 | 13 | 14 | 27 |
| 2014 | 8 | 14 | 22 |
| 2015 | 7 | 10 | 17 |
| 2016 | 8 | 15 | 23 |
| 2017 | 12 | 17 | 29 |
| 2018 | 10 | 11 | 21 |
| 2019 | 9 | 11 | 20 |
| 2020 | 7 | 13 | 20 |
| 2021 | 7 | 10 | 17 |
| 2022 | 4 | 8 | 12 |
| 2023 | 4 | 4 | 8 |
| 2024 | 4 | 6 | 10 |
| 2025 | 2 | 1 | 3 |
Below are the most recent publications written about "DNA Breaks, Double-Stranded" by people in Profiles.
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Multifaceted roles of H2B mono-ubiquitylation in D-loop metabolism during homologous recombination repair. Nucleic Acids Res. 2025 Feb 08; 53(4).
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Multifaceted roles of H2B mono-ubiquitylation in D-loop metabolism during homologous recombination repair. Nucleic Acids Res. 2025 Feb 08; 53(4).
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Disparate Pathways for Extrachromosomal DNA Biogenesis and Genomic DNA Repair. Cancer Discov. 2025 Jan 13; 15(1):69-82.
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Enhancing transcription-replication conflict targets ecDNA-positive cancers. Nature. 2024 Nov; 635(8037):210-218.
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Modeling the oxygen effect in DNA strand break induced by gamma-rays with TOPAS-nBio. Phys Med Biol. 2024 Oct 25; 69(21).
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53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR). Nat Commun. 2024 Oct 05; 15(1):8648.
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TOPAS-Tissue: A Framework for the Simulation of the Biological Response to Ionizing Radiation at the Multi-Cellular Level. Int J Mol Sci. 2024 Sep 19; 25(18).
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The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance. Cell. 2024 Oct 17; 187(21):6055-6070.e22.
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The chromatin-associated 53BP1 ortholog, HSR-9, regulates recombinational repair and X chromosome segregation in the Caenorhabditis elegans germ line. Genetics. 2024 Aug 07; 227(4).
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Increased AID results in mutations at the CRLF2 locus implicated in Latin American ALL health disparities. Nat Commun. 2024 Jul 27; 15(1):6331.