STAT5 Transcription Factor
"STAT5 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.
| Descriptor ID |
D050799
|
| MeSH Number(s) |
D12.644.360.024.342.500 D12.776.157.057.186.500 D12.776.476.024.430.500 D12.776.930.840.500
|
| Concept/Terms |
STAT5 Transcription Factor- STAT5 Transcription Factor
- Factor, STAT5 Transcription
- Transcription Factor, STAT5
- STAT5 Protein
- Signal Transducer and Activator of Transcription 5
STAT5b Transcription Factor- STAT5b Transcription Factor
- Transcription Factor, STAT5b
- STAT5beta Protein
- STAT5b Protein
- Signal Transducer and Activator of Transcription 5B
STAT5a Transcription Factor- STAT5a Transcription Factor
- Transcription Factor, STAT5a
- Mammary Gland Factor
- Signal Transducer and Activator of Transcription 5A
- STAT5alpha Protein
- STAT5a Protein
- Mammary Gland-Specific Nuclear Factor
- Mammary Gland Specific Nuclear Factor
|
Below are MeSH descriptors whose meaning is more general than "STAT5 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "STAT5 Transcription Factor".
This graph shows the total number of publications written about "STAT5 Transcription Factor" by people in this website by year, and whether "STAT5 Transcription Factor" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 6 | 6 |
| 2004 | 0 | 9 | 9 |
| 2005 | 2 | 5 | 7 |
| 2006 | 1 | 4 | 5 |
| 2007 | 2 | 1 | 3 |
| 2008 | 3 | 4 | 7 |
| 2009 | 2 | 1 | 3 |
| 2010 | 4 | 3 | 7 |
| 2011 | 2 | 1 | 3 |
| 2012 | 7 | 2 | 9 |
| 2013 | 2 | 6 | 8 |
| 2014 | 3 | 2 | 5 |
| 2015 | 2 | 7 | 9 |
| 2016 | 1 | 2 | 3 |
| 2017 | 3 | 4 | 7 |
| 2018 | 2 | 2 | 4 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 3 | 3 |
| 2021 | 1 | 3 | 4 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 4 | 4 |
| 2024 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
Below are the most recent publications written about "STAT5 Transcription Factor" by people in Profiles.
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BCL6 coordinates muscle mass homeostasis with nutritional states. Proc Natl Acad Sci U S A. 2025 Jan 28; 122(4):e2408896122.
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PREX1 improves homeostatic proliferation to maintain a naive CD4+ T cell compartment in older age. JCI Insight. 2024 Feb 08; 9(5).
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Distinct roles of hematopoietic cytokines in the regulation of leukemia stem cells in murine MLL-AF9 leukemia. Stem Cell Reports. 2024 01 09; 19(1):100-111.
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Disturbance of sleep maintenance, but not sleep duration, activates nuclear factor-κB and signal transducer and activator of transcription family proteins in older adults: sex differences. Sleep. 2023 10 11; 46(10).
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Expression and prognostic role of STAT5a across cancer types. Biosci Rep. 2023 08 31; 43(8).
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Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation. Nat Immunol. 2023 06; 24(6):1036-1048.
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Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion. J Exp Med. 2022 08 01; 219(8).
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An engineered IL-2 partial agonist promotes CD8+ T cell stemness. Nature. 2021 09; 597(7877):544-548.
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TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nat Commun. 2021 09 09; 12(1):5337.
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Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma. Signal Transduct Target Ther. 2021 09 04; 6(1):333.