STAT3 Transcription Factor
"STAT3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.
| Descriptor ID |
D050796
|
| MeSH Number(s) |
D12.644.360.024.342.300 D12.776.157.057.186.300 D12.776.476.024.430.300 D12.776.930.840.300
|
| Concept/Terms |
STAT3 Transcription Factor- STAT3 Transcription Factor
- Transcription Factor, STAT3
- LIF-Response Factor
- LIF Response Factor
- Acute-Phase Response Factor
- Acute Phase Response Factor
- Response Factor, Acute-Phase
- APRF Transcription Factor
- Transcription Factor, APRF
- Signal Transducer and Activator of Transcription 3
- IL6-Response Factor
- IL6 Response Factor
- STAT3 Protein
STAT3b Transcription Factor- STAT3b Transcription Factor
- Transcription Factor, STAT3b
- Stat3beta Transcription Factor
- Transcription Factor, Stat3beta
STAT3a Transcription Factor- STAT3a Transcription Factor
- Transcription Factor, STAT3a
- Stat3alpha Transcription Factor
- Transcription Factor, Stat3alpha
|
Below are MeSH descriptors whose meaning is more general than "STAT3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "STAT3 Transcription Factor".
This graph shows the total number of publications written about "STAT3 Transcription Factor" by people in this website by year, and whether "STAT3 Transcription Factor" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 4 | 4 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 4 | 4 |
| 1999 | 0 | 5 | 5 |
| 2000 | 0 | 10 | 10 |
| 2001 | 0 | 8 | 8 |
| 2002 | 0 | 9 | 9 |
| 2003 | 0 | 21 | 21 |
| 2004 | 0 | 19 | 19 |
| 2005 | 2 | 9 | 11 |
| 2006 | 14 | 13 | 27 |
| 2007 | 11 | 8 | 19 |
| 2008 | 13 | 15 | 28 |
| 2009 | 11 | 17 | 28 |
| 2010 | 18 | 10 | 28 |
| 2011 | 18 | 20 | 38 |
| 2012 | 17 | 22 | 39 |
| 2013 | 21 | 22 | 43 |
| 2014 | 30 | 21 | 51 |
| 2015 | 24 | 12 | 36 |
| 2016 | 17 | 11 | 28 |
| 2017 | 16 | 17 | 33 |
| 2018 | 11 | 18 | 29 |
| 2019 | 15 | 5 | 20 |
| 2020 | 11 | 10 | 21 |
| 2021 | 9 | 10 | 19 |
| 2022 | 3 | 10 | 13 |
| 2023 | 0 | 5 | 5 |
| 2024 | 3 | 5 | 8 |
| 2025 | 0 | 1 | 1 |
Below are the most recent publications written about "STAT3 Transcription Factor" by people in Profiles.
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Defining Mechanistic Links Between the Non-Coding Variant rs17673553 in CLEC16A and Lupus Susceptibility. Int J Mol Sci. 2025 Jan 01; 26(1).
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Pathobiont-driven antibody sialylation through IL-10 undermines vaccination. J Clin Invest. 2024 Dec 16; 134(24).
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Repurposing an epithelial sodium channel inhibitor as a therapy for murine and human skin inflammation. Sci Transl Med. 2024 Dec 11; 16(777):eade5915.
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pSTAT3 Expression is Increased in Advanced Prostate Cancer in Post-Initiation of Androgen Deprivation Therapy. Prostate. 2025 Feb; 85(3):252-264.
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IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis. Cell Metab. 2024 Oct 01; 36(10):2341-2354.e6.
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Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models. Nutrients. 2024 Jul 22; 16(14).
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STAT3 gain of function: Too much of a good thing in the skin! J Exp Med. 2024 Aug 05; 221(8).
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MiR-653-5p drives osteoarthritis pathogenesis by modulating chondrocyte senescence. Arthritis Res Ther. 2024 May 29; 26(1):111.
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The Janus kinase 1 is critical for pancreatic cancer initiation and progression. Cell Rep. 2024 05 28; 43(5):114202.
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Infusion Product TNFα, Th2, and STAT3 Activities Are Associated with Clinical Responses to Transgenic T-cell Receptor Cell Therapy. Cancer Immunol Res. 2023 12 01; 11(12):1589-1597.