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Alzheimer Disease

"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)


expand / collapse Publications
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
  1. Hospice Use Among Medicare Beneficiaries With Parkinson Disease and Dementia With Lewy Bodies. JAMA Netw Open. 2025 Mar 03; 8(3):e250014.
    View in: PubMed
  2. Evolution of Human Susceptibility to Alzheimer's Disease: A Review of Hypotheses and Comparative Evidence. Evol Anthropol. 2025 Mar; 34(1):e22054.
    View in: PubMed
  3. Deep learning to quantify the pace of brain aging in relation to neurocognitive changes. Proc Natl Acad Sci U S A. 2025 Mar 11; 122(10):e2413442122.
    View in: PubMed
  4. Early Alzheimer's Disease with frequent neuritic plaques harbors neocortical tau seeds distinct from primary age-related tauopathy. Nat Commun. 2025 Feb 21; 16(1):1851.
    View in: PubMed
  5. Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease. Acta Neuropathol Commun. 2025 Feb 15; 13(1):31.
    View in: PubMed
  6. Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer's disease. Nat Med. 2025 Feb; 31(2):574-588.
    View in: PubMed
  7. Searching for the cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer's disease. Commun Biol. 2025 Feb 07; 8(1):195.
    View in: PubMed
  8. Heterogeneous clinical phenotypes of sporadic early-onset Alzheimer's disease: a neuropsychological data-driven approach. Alzheimers Res Ther. 2025 Feb 06; 17(1):38.
    View in: PubMed
  9. Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD. Mol Neurodegener. 2025 Feb 04; 20(1):15.
    View in: PubMed
  10. Alzheimer Disease Blood Biomarkers and Cognition Among Individuals With Diabetes and Overweight or Obesity. JAMA Netw Open. 2025 Feb 03; 8(2):e2458149.
    View in: PubMed