"Liver X Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating cholesterol homeostasis, ENERGY METABOLISM; INFLAMMATION; and the immune response.
| Descriptor ID |
D000071518
|
| MeSH Number(s) |
D12.776.260.531 D12.776.826.194
|
| Concept/Terms |
Liver X Receptors- Liver X Receptors
- Nuclear Oxysterol Receptors
- Oxysterol Receptors, Nuclear
- Liver X Receptor
Liver X Receptor Alpha- Liver X Receptor Alpha
- Liver X Receptor-Alpha
- NR1H3 Protein
- LXRalpha Protein
- Nuclear Orphan Receptor LXR-Alpha
- Nuclear Orphan Receptor LXR Alpha
- Oxysterols Receptor LXR-Alpha
- LXR-Alpha, Oxysterols Receptor
- Oxysterols Receptor LXR Alpha
- Nuclear Receptor Subfamily 1, Group H, Member 3
- LXR-Alpha Protein
- LXR Alpha Protein
Liver X Receptor Beta- Liver X Receptor Beta
- Liver X Receptor-Beta
- Nuclear Receptor Subfamily 1, Group H, Member 2
- Oxysterols Receptor LXR-Beta
- LXR-Beta, Oxysterols Receptor
- Oxysterols Receptor LXR Beta
- LXRbeta Protein
- NR1H2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Liver X Receptors".
Below are MeSH descriptors whose meaning is more specific than "Liver X Receptors".
This graph shows the total number of publications written about "Liver X Receptors" by people in this website by year, and whether "Liver X Receptors" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 5 | 5 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 11 | 11 |
| 2004 | 0 | 10 | 10 |
| 2005 | 0 | 11 | 11 |
| 2006 | 0 | 14 | 14 |
| 2007 | 0 | 7 | 7 |
| 2008 | 0 | 11 | 11 |
| 2009 | 0 | 16 | 16 |
| 2010 | 0 | 12 | 12 |
| 2011 | 0 | 8 | 8 |
| 2012 | 0 | 11 | 11 |
| 2013 | 0 | 8 | 8 |
| 2014 | 1 | 6 | 7 |
| 2015 | 0 | 5 | 5 |
| 2016 | 3 | 6 | 9 |
| 2017 | 3 | 2 | 5 |
| 2018 | 6 | 1 | 7 |
| 2019 | 1 | 3 | 4 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 3 | 4 |
| 2023 | 0 | 2 | 2 |
| 2024 | 5 | 1 | 6 |
Below are the most recent publications written about "Liver X Receptors" by people in Profiles.
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TOMM40 regulates hepatocellular and plasma lipid metabolism via an LXR-dependent pathway. Mol Metab. 2024 Dec; 90:102056.
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Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health. Nat Metab. 2024 Oct; 6(10):1922-1938.
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LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes. J Clin Invest. 2024 Aug 15; 134(16).
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LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes. J Clin Invest. 2024 05 15; 134(10).
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Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses. Adv Sci (Weinh). 2024 May; 11(20):e2307201.
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TRIM13 reduces cholesterol efflux and increases oxidized LDL uptake leading to foam cell formation and atherosclerosis. J Biol Chem. 2024 May; 300(5):107224.
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Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake. Science. 2023 11 10; 382(6671):eadf0966.
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Development of Light-Activated LXR Agonists. ChemMedChem. 2023 06 01; 18(11):e202200647.
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Hepatic GATA4 regulates cholesterol and triglyceride homeostasis in collaboration with LXRs. Genes Dev. 2022 Nov-Dec 1; 36(21-24):1129-1144.
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LXR agonist improves peripheral neuropathy and modifies PNS immune cells in aged mice. J Neuroinflammation. 2022 Feb 26; 19(1):57.