"Replication Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single-stranded DNA-binding protein that is found in EUKARYOTIC CELLS. It is required for DNA REPLICATION; DNA REPAIR; and GENETIC RECOMBINATION.
| Descriptor ID |
D051716
|
| MeSH Number(s) |
D12.776.260.700
|
| Concept/Terms |
Replication Protein A- Replication Protein A
- Single-Strand Binding Protein RP-A
- Single Strand Binding Protein RP A
- Replication Factor A Single-Stranded DNA-Binding Protein
- Replication Factor A Single Stranded DNA Binding Protein
- Replication Factor A
- DNA Replication Factor A
|
Below are MeSH descriptors whose meaning is more general than "Replication Protein A".
Below are MeSH descriptors whose meaning is more specific than "Replication Protein A".
This graph shows the total number of publications written about "Replication Protein A" by people in this website by year, and whether "Replication Protein A" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 8 | 8 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 3 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 3 | 3 | 6 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 5 | 7 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 2 | 3 |
| 2015 | 2 | 4 | 6 |
| 2016 | 2 | 2 | 4 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Replication Protein A" by people in Profiles.
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Enhancing transcription-replication conflict targets ecDNA-positive cancers. Nature. 2024 Nov; 635(8037):210-218.
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BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA. Proc Natl Acad Sci U S A. 2023 04 04; 120(14):e2221971120.
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DNA repair gene expression is increased in HPV positive head and neck squamous cell carcinomas. Virology. 2020 09; 548:174-181.
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ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex. Nat Commun. 2019 11 22; 10(1):5304.
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Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage. Mol Cell. 2017 Oct 19; 68(2):431-445.e5.
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Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex. J Biol Chem. 2017 07 14; 292(28):11702-11713.
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Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament. Nucleic Acids Res. 2017 01 25; 45(2):749-761.
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Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes. J Biol Chem. 2017 Jan 06; 292(1):217-228.
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RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together. Mol Cell. 2016 12 01; 64(5):951-966.
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Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line. PLoS Genet. 2016 Apr; 12(4):e1005985.