"Plectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.
| Descriptor ID |
D051190
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| MeSH Number(s) |
D12.776.220.790.750 D12.776.744.736
|
| Concept/Terms |
Plectin- Plectin
- Hemidesmosomal Protein HD1
- HD1, Hemidesmosomal Protein
- 500-kDa HD1 Protein
- 500 kDa HD1 Protein
- HD1 Protein, 500-kDa
|
Below are MeSH descriptors whose meaning is more general than "Plectin".
Below are MeSH descriptors whose meaning is more specific than "Plectin".
This graph shows the total number of publications written about "Plectin" by people in this website by year, and whether "Plectin" was a major or minor topic of these publications.
Below are the most recent publications written about "Plectin" by people in Profiles.
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Evaluation of Systemic Gentamicin as Translational Readthrough Therapy for a Patient With Epidermolysis Bullosa Simplex With Muscular Dystrophy Owing to PLEC1 Pathogenic Nonsense Variants. JAMA Dermatol. 2022 04 01; 158(4):439-443.
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A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements. Science. 2021 05 14; 372(6543).
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Plectin is a regulator of prostate cancer growth and metastasis. Oncogene. 2021 01; 40(3):663-676.
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GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med. 2018 03 05; 215(3):941-961.
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Plectin-1 as a Biomarker of Malignant Progression in Intraductal Papillary Mucinous Neoplasms: A Multicenter Study. Pancreas. 2016 10; 45(9):1353-8.
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Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model. Stem Cells. 2014 Jul; 32(7):1865-77.
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The RON-receptor regulates pancreatic cancer cell migration through phosphorylation-dependent breakdown of the hemidesmosome. Int J Cancer. 2012 Oct 15; 131(8):1744-54.
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Congenital myasthenic syndrome associated with epidermolysis bullosa caused by homozygous mutations in PLEC1 and CHRNE. Clin Genet. 2011 Nov; 80(5):444-51.
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Blinded by the light: molecular imaging in pancreatic adenocarcinoma. Clin Cancer Res. 2011 Jan 15; 17(2):203-5.
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Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. J Cell Sci. 2009 May 01; 122(Pt 9):1390-400.