Receptors, Proteinase-Activated
"Receptors, Proteinase-Activated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of receptors that are activated by the action of PROTEINASES. The most notable examples are the THROMBIN RECEPTORS. The receptors contain cryptic ligands that are exposed upon the selective proteolysis of specific N-terminal cleavage sites.
| Descriptor ID |
D044462
|
| MeSH Number(s) |
D12.776.543.750.792
|
| Concept/Terms |
Receptors, Proteinase-Activated- Receptors, Proteinase-Activated
- Receptors, Proteinase Activated
- Protease-Activated Receptors
- Protease Activated Receptors
- Receptors, Protease-Activated
- Proteinase-Activated Receptors
- Proteinase Activated Receptors
- Endopeptidase-Activated Receptors
- Endopeptidase Activated Receptors
- Receptors, Endopeptidase-Activated
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Proteinase-Activated".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Proteinase-Activated".
This graph shows the total number of publications written about "Receptors, Proteinase-Activated" by people in this website by year, and whether "Receptors, Proteinase-Activated" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 1 | 3 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 2 | 4 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 2 | 4 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 2 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 3 | 4 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Proteinase-Activated" by people in Profiles.
-
Staphylococcus aureus: The Bug Behind the Itch in Atopic Dermatitis. J Invest Dermatol. 2024 May; 144(5):950-953.
-
Protease-activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography. J Thromb Haemost. 2023 08; 21(8):2236-2247.
-
Protease Activated Receptors: A Pathway to Boosting Mesenchymal Stromal Cell Therapeutic Efficacy in Acute Respiratory Distress Syndrome? Int J Mol Sci. 2022 Jan 24; 23(3).
-
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets. Physiol Rev. 2021 04 01; 101(2):545-567.
-
Plasminogen Receptors in Human Malignancies: Effects on Prognosis and Feasibility as Targets for Drug Development. Curr Drug Targets. 2020; 21(7):647-656.
-
Neuroprotection and vasculoprotection using genetically targeted protease-ligands. Brain Res. 2019 07 15; 1715:13-20.
-
Tissue-type plasminogen activator neutralizes LPS but not protease-activated receptor-mediated inflammatory responses to plasmin. J Leukoc Biol. 2019 04; 105(4):729-740.
-
GPCRs in Cancer: Protease-Activated Receptors, Endocytic Adaptors and Signaling. Int J Mol Sci. 2018 Jun 27; 19(7).
-
Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs. Nat Commun. 2015 Jul 28; 6:7864.
-
Protease-activated receptors and itch. Handb Exp Pharmacol. 2015; 226:219-35.