"Semaphorin-3A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.
| Descriptor ID |
D040121
|
| MeSH Number(s) |
D12.644.276.923.374 D12.776.467.923.374 D23.529.923.374
|
| Concept/Terms |
Semaphorin-3A- Semaphorin-3A
- Sem D
- Semaphorin D
- Collapsin-1
- Collapsin 1
- Sema3A
- Semaphorin 3A
- Collapsing Factor
- Collapsin
|
Below are MeSH descriptors whose meaning is more general than "Semaphorin-3A".
Below are MeSH descriptors whose meaning is more specific than "Semaphorin-3A".
This graph shows the total number of publications written about "Semaphorin-3A" by people in this website by year, and whether "Semaphorin-3A" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 2 | 3 |
| 2011 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
Below are the most recent publications written about "Semaphorin-3A" by people in Profiles.
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Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution. Nat Commun. 2021 11 30; 12(1):6990.
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Semaphorin-3A inhibits multiple myeloma progression in a mouse model. Carcinogenesis. 2018 10 08; 39(10):1283-1291.
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miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non-Cell-Autonomous Mechanism in ALS. J Neurosci. 2018 06 13; 38(24):5478-5494.
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Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum. Neuron. 2018 02 21; 97(4):796-805.e5.
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Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. PLoS Genet. 2017 Oct; 13(10):e1007048.
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A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis. Development. 2017 10 15; 144(20):3744-3754.
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Cardiac innervation and sudden cardiac death. Circ Res. 2015 Jun 05; 116(12):2005-19.
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Semaphorin3a promotes advanced diabetic nephropathy. Diabetes. 2015 May; 64(5):1743-59.
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Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature. 2014 May 08; 509(7499):189-94.
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Semaphorin 3A alters endothelial cell immunogenicity by regulating Class II transactivator activity circuits. Transfusion. 2014 Aug; 54(8):1961-70.