Dendritic Cells, Follicular
"Dendritic Cells, Follicular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-hematopoietic cells, with extensive dendritic processes, found in the primary and secondary follicles of lymphoid tissue (the B cell zones). They are different from conventional DENDRITIC CELLS associated with T-CELLS. They are derived from MESENCHYMAL STEM CELLS and are negative for class II MHC antigen and do not process or present antigen like the conventional dendritic cells do. Instead, follicular dendritic cells have FC RECEPTORS and C3B RECEPTORS that hold antigen in the form of ANTIGEN-ANTIBODY COMPLEXES on their surfaces for long periods for recognition by B-CELLS.
| Descriptor ID |
D020566
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| MeSH Number(s) |
A10.549.400.500.200 A11.066.275 A15.382.066.275 A15.382.520.604.412.500.200
|
| Concept/Terms |
Dendritic Cells, Follicular- Dendritic Cells, Follicular
- Dendritic Cell, Follicular
- Follicular Dendritic Cell
- Follicular Dendritic Cells
- Dendritic Reticulum Cells, Follicular
|
Below are MeSH descriptors whose meaning is more general than "Dendritic Cells, Follicular".
Below are MeSH descriptors whose meaning is more specific than "Dendritic Cells, Follicular".
This graph shows the total number of publications written about "Dendritic Cells, Follicular" by people in this website by year, and whether "Dendritic Cells, Follicular" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 0 | 2 |
| 2002 | 1 | 1 | 2 |
| 2004 | 2 | 0 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2021 | 2 | 1 | 3 |
Below are the most recent publications written about "Dendritic Cells, Follicular" by people in Profiles.
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Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation. Immunity. 2021 10 12; 54(10):2256-2272.e6.
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Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity. Nat Immunol. 2021 05; 22(5):639-653.
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Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues. Nat Immunol. 2021 05; 22(5):571-585.
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Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity. Immunity. 2018 05 15; 48(5):1014-1028.e6.
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The G protein-coupled receptor P2RY8 and follicular dendritic cells promote germinal center confinement of B cells, whereas S1PR3 can contribute to their dissemination. J Exp Med. 2015 Dec 14; 212(13):2213-22.
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Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitness. J Immunol. 2014 May 15; 192(10):4601-9.
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Inducible bronchus-associated lymphoid tissue (iBALT) synergizes with local lymph nodes during antiviral CD4+ T cell responses. Lymphat Res Biol. 2013 Dec; 11(4):196-202.
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Human tonsil-derived follicular dendritic-like cells are refractory to human prion infection in vitro and traffic disease-associated prion protein to lysosomes. Am J Pathol. 2014 Jan; 184(1):64-70.
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Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity. Immunity. 2013 Apr 18; 38(4):782-91.
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Follicular dendritic cells: origin, function, and different disease-associated patterns. Hum Pathol. 2013 Jun; 44(6):937-50.