"Germinal Center" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T-LYMPHOCYTES, HELPER-INDUCER) are stimulated to generate memory cells.
| Descriptor ID |
D018858
|
| MeSH Number(s) |
A10.549.400.500 A15.382.520.604.412.500
|
| Concept/Terms |
Germinal Center- Germinal Center
- Center, Germinal
- Centers, Germinal
- Germinal Centers
|
Below are MeSH descriptors whose meaning is more general than "Germinal Center".
Below are MeSH descriptors whose meaning is more specific than "Germinal Center".
This graph shows the total number of publications written about "Germinal Center" by people in this website by year, and whether "Germinal Center" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 2 | 3 |
| 1999 | 1 | 1 | 2 |
| 2000 | 3 | 3 | 6 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 6 | 6 |
| 2003 | 0 | 1 | 1 |
| 2004 | 2 | 2 | 4 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 4 | 6 |
| 2007 | 6 | 4 | 10 |
| 2008 | 2 | 2 | 4 |
| 2009 | 5 | 4 | 9 |
| 2010 | 3 | 5 | 8 |
| 2011 | 7 | 10 | 17 |
| 2012 | 6 | 5 | 11 |
| 2013 | 9 | 6 | 15 |
| 2014 | 11 | 5 | 16 |
| 2015 | 14 | 6 | 20 |
| 2016 | 14 | 10 | 24 |
| 2017 | 12 | 4 | 16 |
| 2018 | 6 | 3 | 9 |
| 2019 | 11 | 7 | 18 |
| 2020 | 8 | 14 | 22 |
| 2021 | 9 | 7 | 16 |
| 2022 | 5 | 3 | 8 |
| 2023 | 0 | 5 | 5 |
| 2024 | 4 | 3 | 7 |
Below are the most recent publications written about "Germinal Center" by people in Profiles.
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Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis. Immunity. 2024 12 10; 57(12):2772-2789.e8.
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The protozoan commensal Tritrichomonas musculis is a natural adjuvant for mucosal IgA. J Exp Med. 2024 Dec 02; 221(12).
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BAFF promotes follicular helper T cell development and germinal center formation through BR3 signal. JCI Insight. 2024 Nov 08; 9(21).
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Gastrointestinal germinal center B cell depletion and reduction in IgA+ plasma cells in HIV-1 infection. Sci Immunol. 2024 Oct 25; 9(100):eado0090.
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Immunological memory diversity in the human upper airway. Nature. 2024 Aug; 632(8025):630-636.
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Affinity gaps among B cells in germinal centers drive the selection of MPER precursors. Nat Immunol. 2024 Jun; 25(6):1083-1096.
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Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates. Science. 2024 May 17; 384(6697):eadj8321.
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Spatially-resolved transcriptomics reveal macrophage heterogeneity and prognostic significance in diffuse large B-cell lymphoma. Nat Commun. 2024 Mar 08; 15(1):2113.
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To whom B cells toll extrafollicular responses. Genes Immun. 2023 12; 24(6):285-286.
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A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates. Nat Commun. 2023 11 04; 14(1):7107.