"Troponin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the minor protein components of skeletal and cardiac muscles. It functions as the calcium-binding component in a complex with BETA-TROPOMYOSIN; ACTIN; and MYOSIN and confers calcium sensitivity to the cross-linked actin and myosin filaments. Troponin itself is a complex of three regulatory proteins (TROPONIN C; TROPONIN I; and TROPONIN T).
| Descriptor ID |
D014336
|
| MeSH Number(s) |
D05.500.945 D05.750.078.730.825 D12.776.210.500.910 D12.776.220.525.825
|
| Concept/Terms |
Troponin- Troponin
- Troponins
- Troponin Complex
|
Below are MeSH descriptors whose meaning is more general than "Troponin".
Below are MeSH descriptors whose meaning is more specific than "Troponin".
This graph shows the total number of publications written about "Troponin" by people in this website by year, and whether "Troponin" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 4 | 0 | 4 |
| 1997 | 1 | 2 | 3 |
| 1998 | 4 | 1 | 5 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2002 | 4 | 2 | 6 |
| 2003 | 0 | 3 | 3 |
| 2004 | 3 | 5 | 8 |
| 2005 | 2 | 4 | 6 |
| 2006 | 2 | 3 | 5 |
| 2007 | 3 | 1 | 4 |
| 2008 | 3 | 2 | 5 |
| 2009 | 4 | 2 | 6 |
| 2010 | 3 | 3 | 6 |
| 2011 | 2 | 4 | 6 |
| 2012 | 0 | 3 | 3 |
| 2013 | 6 | 10 | 16 |
| 2014 | 7 | 4 | 11 |
| 2015 | 5 | 3 | 8 |
| 2016 | 5 | 2 | 7 |
| 2017 | 8 | 10 | 18 |
| 2018 | 6 | 4 | 10 |
| 2019 | 6 | 5 | 11 |
| 2020 | 4 | 3 | 7 |
| 2021 | 3 | 5 | 8 |
| 2022 | 3 | 11 | 14 |
| 2023 | 1 | 5 | 6 |
| 2024 | 2 | 5 | 7 |
Below are the most recent publications written about "Troponin" by people in Profiles.
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Cardiac troponin elevation and mortality in takotsubo syndrome: New insights from the international takotsubo registry. Eur J Clin Invest. 2024 Dec; 54(12):e14317.
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24-hour Telemetry Monitoring May Not be Necessary for Patients With an Isolated Sternal Fracture and Minor ECG Abnormalities or Troponin Elevation: A Southern California Multicenter Study. Am Surg. 2025 Jan; 91(1):126-132.
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Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility. J Med Chem. 2024 May 23; 67(10):7825-7835.
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Intensive Blood Pressure Lowering in Individuals With Low Diastolic Blood Pressure and Elevated Troponin Levels in SPRINT. J Am Heart Assoc. 2024 Mar 19; 13(6):e032493.
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Cardiac Troponin Activator CK-963 Increases Cardiac Contractility in Rats. J Med Chem. 2024 May 23; 67(10):7859-7869.
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Tirasemtiv enhances submaximal muscle tension in an Acta1:p.Asp286Gly mouse model of nemaline myopathy. J Gen Physiol. 2024 Apr 01; 156(4).
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Emerging Biomarkers in the Laboratory and in Practice: A Novel Approach to Diagnosing Heart Failure in Diabetes. J Diabetes Sci Technol. 2024 May; 18(3):733-740.
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Evolution of Cardiovascular Findings in Multisystem Inflammatory Syndrome in Children (MIS-C) Across COVID-19 Variants: Common Trends and Unusual Presentations. Pediatr Cardiol. 2024 Mar; 45(3):552-559.
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Emergency Department Cardiac Risk Stratification With High-Sensitivity vs Conventional Troponin HEART Pathway. JAMA Netw Open. 2023 12 01; 6(12):e2348351.
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HEART Score Recalibration Using Higher Sensitivity Troponin T. Ann Emerg Med. 2023 10; 82(4):449-462.